Peter Norman Culshaw

Synthesis and decomposition studies of dialkyltellurides of type RTeR′

Publisher: Elsevier BV

Date: 1991

DOI: 10.1016/0022-0248(91)90478-N

Generation of sulphonyl radicals from sulphonate esters

Publisher: Elsevier BV

Date: 1990

DOI: 10.1016/S0040-4039(00)97388-X

The synthesis of archaebacterial lipid analogues

Publisher: Elsevier BV

Date: 04-2000

DOI: 10.1016/S0040-4039(00)00283-5

Rearrangement of radicals derived from bicyclo[5.1.0]octa-2,4-diene, tricyclo[6.1.0.02,4]nona-6-ene and tetracyclo[7.1.0.02,4.05,7]decane

Publisher: Royal Society of Chemistry (RSC)

Date: 1990

DOI: 10.1039/P29900000531

Methamphetamine contamination in residential properties and their remediation in Queensland, Australia

Publisher: Elsevier BV

Date: 07-2023

DOI: 10.1016/J.FSIR.2023.100311

Regioselectivity in the formation of cyclic sulphones from 4- and 5-alkenesulphonyl chlorides

Publisher: Elsevier BV

Date: 1990

DOI: 10.1016/S0040-4039(00)97084-9

Enantiomeric profiling of amphetamine and methamphetamine in wastewater: A 7-year study in regional and urban Queensland, Australia.

Publisher: Elsevier BV

Date: 12-2018

DOI: 10.1016/J.SCITOTENV.2018.06.242

Abstract: Enantiomeric profiling was used in this study to investigate the consumption of hetamine and meth hetamine in regional and urban Southeast Queensland, Australia over a period of seven years. S(+) meth hetamine was predominantly consumed in both urban and regional areas, showing a two and three fold increase in urban and regional catchments respectively between 2011 and 2017. The ratio of hetamine to meth hetamine (AMP/METH) in wastewater reflected the expected excretion profile of meth hetamine consumption indicating the presence of hetamine in this study was primarily the result of meth hetamine metabolism. However, the occasional occurrence of R(-) hetamine in s les containing higher AMP/METH ratios, suggested the consumption of racemic hetamine. The R(-) meth hetamine enantiomer was also identified in several s les, possibly indicative that the phenyl-2-propanone (P2P) synthesis process rather than the more typical reduction of ephedrines was also being used to manufacture meth hetamine. Furthermore, we identified two s les with a significantly different enantiomer ratio for the METH and AMP as well as a much lower AMP/METH concentration ratio suggesting contribution from direct disposal of meth hetamine into the sewer. This study demonstrated that enantiomeric profiling in wastewater-based epidemiology can provide valuable information for evaluating the origin of hetamine in wastewater as either a metabolite of meth hetamine consumption or hetamine itself.

Multi-drug cocktails: Impurities in commonly used illicit drugs seized by police in Queensland, Australia

Publisher: Elsevier BV

Date: 08-2019

DOI: 10.1016/J.DRUGALCDEP.2019.03.019

Abstract: Impurities in commonly used illicit drugs raise concerns for unwitting consumers when pharmacologically active adulterants, especially new psychoactive substances (NPS), are used. This study examines impurities detected in illicit drugs seized in one Australian jurisdiction. Queensland Health Forensic and Scientific Services provided analytical data. Data described the chemical composition of 9346 s les of 11 illicit drugs seized by police during 2015-2016. Impurities present in primary drugs were summarized and tabulated. A systematic search for published evidence reporting similar analyses was conducted. Meth hetamine was the primary drug in 6608 s les, followed by MDMA (1232 s les) and cocaine (516 s les). Purity of primary drugs ranged from ∼30% for cocaine, 2-CB and GHB to >90% for THC, meth hetamine, heroin and MDMA. Meth hetamine and MDMA contained the largest variety of impurities: 22 and 18 variants, respectively. Drug adulteration patterns were broadly similar to those found elsewhere, including NPS, but in some primary drugs impurities were found which had not been reported elsewhere. Psychostimulants were adulterated with each other. Levamisole was a common impurity in cocaine. Psychedelics were adulterated with meth hetamine and NPS. Opioids were quite pure, but some s les contained meth hetamine and synthetic opioids. Impurities detected were mostly pharmacologically active adulterants probably added to enhance desired effects or for active bulking. Given the designer nature of these drug cocktails, the effects of the adulterated drugs on users from possible complex multi-drug interactions is unpredictable. Awareness-raising among users, research into complex multi-drug effects and ongoing monitoring is required.

Homolytic reactions of diorganotellurium and diorganoditellurium compounds in solution; an EPR study

Publisher: Elsevier BV

Date: 06-1992

DOI: 10.1016/0022-328X(92)80094-E

Studies of the formation and stability of pentadienyl and 3-substituted pentadienyl radicals

Publisher: American Chemical Society (ACS)

Date: 09-1991

DOI: 10.1021/JO00019A012

Investigation of the l-phenylacetylcarbinol process to substituted benzaldehydes of interest

Publisher: Elsevier BV

Date: 02-2014

DOI: 10.1016/J.FORSCIINT.2013.11.017

Abstract: The large scale industrial manufacture of the nasal decongestant pseudoephedrine is typically carried out by the reductive amination of l-phenylacetylcarbinol (l-PAC), which in turn is produced via the biotransformation of benzaldehyde using yeast. In recent years there has been increasing legislative control of the supply of pseudoephedrine due to it being erted for the clandestine production of methyl hetamine and there is some evidence that a number of clandestine drug laboratory chemists have considered the application of the l-PAC process to manufacture their own pseudoephedrine. This work examined the use of a number of substituted benzaldehydes for the manufacture of the corresponding substituted l-PAC analogue followed by reductive amination to the corresponding substituted pseudoephedrine/ephedrine analogues. These substituted pseudoephedrine/ephedrine analogues were either reduced or oxidised to determine the feasibility of producing the corresponding methyl hetamine or methcathinone analogues. As a result, the l-PAC process was identified as a viable route for synthesis of substituted methyl hetamines and methcathinones.

Australian National University

Location: Australia

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CSIRO

Location: Australia

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Griffith University

Location: Australia

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Forensic And Scientific Services

Location: Australia

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TAFE Queensland Brisbane

Location: Australia

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Sheffield Hallam University

Location: United Kingdom of Great Britain and Northern Ireland

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UNSW Australia

Location: Australia

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University Of St Andrews

Location: United Kingdom of Great Britain and Northern Ireland

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University Of St Andrews

Location: No location found

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UNSW Sydney

Location: Australia

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Linkage Projects - Grant ID: LP220100058

Start Date: 02-2024

End Date: 02-2027

Amount: $259,608.00

Funder: Australian Research Council

Understanding Third Hand Exposure Of Australian People To Methamphetamine

Start Date: 2021

End Date: 2023

Funder: Australian Research Council

Linkage Projects - Grant ID: LP200200591

Start Date: 04-2022

End Date: 04-2025

Amount: $296,579.00

Funder: Australian Research Council