ORCID Profile
0000-0002-6811-9126
Current Organisation
University of California, San Francisco
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Research Topics
In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Top 5 Research Topics
ANZSRC Field of Research (FoR)
Materials Engineering | Textile Technology | Functional Materials | Composite and Hybrid Materials | Manufacturing Processes and Technologies (excl. Textiles) | Industrial Chemistry | Manufacturing Engineering | Organic Chemistry | Organic Green Chemistry | Bioprocessing, Bioproduction and Bioproducts |
ANZSRC Socio-Economic Objective (SEO)
Natural Fibres, Yarns and Fabrics | Expanding Knowledge in Technology | Expanding Knowledge in Engineering | Management of Solid Waste from Plant Production | Inorganic Industrial Chemicals | Blood Disorders | Synthetic Fibres, Yarns and Fabrics | Organic Industrial Chemicals (excl. Resins, Rubber and Plastics) | Environmentally Sustainable Manufacturing not elsewhere classified | Hearing, Vision, Speech and Their Disorders
Related Links
Publications
Effect of aqueous glycine treatment on the fine structure and dyeing ability of cotton
Publisher: Elsevier BV
Date: 12-2018
DOI: 10.1016/J.CARBPOL.2018.08.057
Abstract: Exhaustion dyeing of cotton means a significant proportion of dyestuff is not fixed onto the material and is drained out when the dyebath is emptied. This waste presents issues for dye houses in terms of remediating water quality and the loss of expensive dye chemicals. Work to improve the dyeing ability of cotton has been limited to modifying cotton's cellulose structure by, notionally, environmentally hazardous treatments, e.g., concentrated caustic soda. Here we use a buffered, aqueous glycine treatment to improve the dyeing ability of cotton. The treated cotton showed improved dye absorption compared with control s les. An investigation of the structure of the treated cotton using Fourier Transform Infrared spectroscopy (FTIR) and
The effect of fibrous structural difference on thermal insulation properties of biological composites: Silkworm cocoons
Publisher: SAGE Publications
Date: 22-07-2016
Abstract: As a biological fibrous structure, silkworm cocoon provides multiple protective functionalities to safeguard the silk moth pupa’s metabolic activity. The mechanism of this protection could be adopted in clothing manufacture to provide more comfortable apparel. In this study, the thermal insulation properties of both domestic Bombyx mori ( B. mori) and wild Antheraea pernyi ( A. pernyi) cocoons were investigated under both warm and cold environmental conditions. Computational fluid dynamics models have been developed to simulate the heat transfer process through both types of cocoon wall structures. The simulation results show that the wild A. pernyi cocoon reduces the intensity of convection and heat flux between the environment and the cocoon interior and has higher wind resistance than its domestic counterpart. Compared with A. pernyi cocoon, the B. mori cocoon facilitates easy air transfer and decreases the temperature lag when the surrounding conditions are changed. The new knowledge has significant implications for developing biomimetic thermal functional materials.
1000 spider silkomes: Linking sequences to silk physical properties
Publisher: American Association for the Advancement of Science (AAAS)
Date: 14-10-2022
Abstract: Spider silks are among the toughest known materials and thus provide models for renewable, biodegradable, and sustainable biopolymers. However, the entirety of their ersity still remains elusive, and silks that exceed the performance limits of industrial fibers are constantly being found. We obtained transcriptome assemblies from 1098 species of spiders to comprehensively catalog silk gene sequences and measured the mechanical, thermal, structural, and hydration properties of the dragline silks of 446 species. The combination of these silk protein genotype-phenotype data revealed essential contributions of multicomponent structures with major ullate spidroin 1 to 3 paralogs in high-performance dragline silks and numerous amino acid motifs contributing to each of the measured properties. We hope that our global s ling, comprehensive testing, integrated analysis, and open data will provide a solid starting point for future biomaterial designs.
Improving the Tensile Properties of Wet Spun Silk Fibers Using Rapid Bayesian Algorithm
Publisher: American Chemical Society (ACS)
Date: 09-04-2020
Intrinsic tensile properties of cocoon silk fibres can be estimated by removing flaws through repeated tensile tests
Publisher: The Royal Society
Date: 06-2015
Abstract: Silk fibres from silkworm cocoons have lower strength than spider silk and have received less attention as a source of high-performance fibres. In this work, we have used an innovative procedure to eliminate the flaws gradually of a single fibre specimen by retesting the unbroken portion of the fibre, after each fracture test. This was done multiple times so that the final test may provide the intrinsic fibre strength. During each retest, the fibre specimen began to yield once the failure load of the preceding test was exceeded. For each fibre specimen, a composite curve was constructed from multiple tests. The composite curves and analysis show that strengths of mass-produced Muga and Eri cocoon silk fibres increased from 446 to 618 MPa and from 337 to 452 MPa, respectively. Similarly, their toughness increased from 84 to 136 MJ m −3 and from 61 to 104 MJ m −3 , respectively. Composite plots produced significantly less inter-specimen variations compared to values from single tests. The fibres with reduced flaws as a result of retests in the tested section have a tensile strength and toughness comparable to naturally spun dragline spider silk with a reported strength of 574 MPa and toughness of 91–158 MJ m −3 , which is used as a benchmark for developing high-performance fibres. This retesting approach is likely to provide useful insights into discrete flaw distributions and intrinsic mechanical properties of other fatigue-resistant materials.
Structure and properties of biomedical films prepared from aqueous and acidic silk fibroin solutions
Publisher: Wiley
Date: 09-02-2011
DOI: 10.1002/JBM.A.33021
Facile and versatile solid state surface modification of silk fibroin membranes using click chemistry
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8TB02508H
Abstract: Reported is a fast and versatile protocol to surface modify pre-cast silk membranes targeting tyrosine residues.
Silkworm cocoon as natural material and structure for thermal insulation
Publisher: Elsevier BV
Date: 08-2013
Fabrication of ultrafine powder from eri silk through attritor and jet milling
Publisher: Elsevier BV
Date: 04-2009
Correction: Protein paper from exfoliated eri silk nanofibers (Biomacromolecules (2020) 21:3 (1303-1314) DOI: 10.1021/acs.biomac.0c00097)
Publisher: American Chemical Society (ACS)
Date: 02-04-2020
An investigation into transition metal ion binding properties of silk fibers and particles using radioisotopes
Publisher: Wiley
Date: 30-09-2010
DOI: 10.1002/APP.33059
Exploring novel ultrafine Eri silk bioscaffold for enzyme stabilisation in cellobiose hydrolysis
Publisher: Elsevier BV
Date: 10-2013
DOI: 10.1016/J.BIORTECH.2013.01.065
Abstract: The suitability of optimised ultrafine Eri silk microparticles as novel enzyme supports was studied for potential application in biofuel production. β-glucosidase (BGL) from Aspergillus niger was immobilised on Eri silk fibrion particles via an adsorption method resulting in a 62% immobilisation yield. Soluble and immobilised enzymes exhibited pH-optima at pH 4.0 and 5.0, respectively with optimum activity at 60°C. The Michaelis constant (K(M)) was 0.16 and 0.27 mM for soluble and immobilised BGL respectively. The immobilisation support has a protective effect on the enzyme by increasing rigidity this is reflected by an increase in stability under thermal denaturation at 70°C. Immobilised enzyme retained more than 50% of initial activity for up to eight cycles. Maximum cellobiose hydrolysis by immobilised BGL was achieved at 20 h. Crystalline ultrafine Eri silk particles were found to be a promising viable, environmentally sound and stable matrix for binding BGL for cellobiose hydrolysis.
Protein Paper from Exfoliated Eri Silk Nanofibers
Publisher: American Chemical Society (ACS)
Date: 06-02-2020
Surface energy of silk fibroin and mechanical properties of silk cocoon composites
Publisher: Royal Society of Chemistry (RSC)
Date: 2015
DOI: 10.1039/C4RA09482D
Abstract: Both the physical and physiochemical properties of domestic and wild silkworm silk fibroin were studied, including surface energy and surface energy heterogeneity.
Nanovoid formation induces property variation within and across individual silkworm silk threads
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2TB00357K
Abstract: Silk is a unique fiber, having a strength and toughness that exceeds other natural fibers.
3D Printing of Silk Particle-Reinforced Chitosan Hydrogel Structures and Their Properties
Publisher: American Chemical Society (ACS)
Date: 20-07-2018
Relationship between processing, surface energy and bulk properties of ultrafine silk particles
Publisher: Elsevier BV
Date: 2015
Preparing Bombyx mori Silk Nanofibers Using a Sustainable and Scalable Approach
Publisher: American Chemical Society (ACS)
Date: 16-12-2020
Enhancing Resistance of Silk Fibroin Material to Enzymatic Degradation by Cross-Linking Both Crystalline and Amorphous Domains
Publisher: American Chemical Society (ACS)
Date: 05-02-2020
Effect of solvent on ionic liquid dissolved regenerated antheraea assamensis silk fibroin
Publisher: Wiley
Date: 04-11-2012
DOI: 10.1002/APP.38666
Reinforcing Silk Scaffolds with Silk Particles
Publisher: Wiley
Date: 09-06-2010
Silk particles, microfibres and nanofibres: A comparative study of their functions in 3D printing hydrogel scaffolds
Publisher: Elsevier BV
Date: 10-2019
DOI: 10.1016/J.MSEC.2019.109784
Abstract: Silk, with highly crystalline structure and well-documented biocompatibility, is promising to be used as reinforcing material and build functionalized composite scaffolds. In the present study, we developed chitosan/silk composite scaffolds using silk particles, silk microfibres and nanofibres via 3D printing method. The three forms of silk fillers with varied shapes and dimensions were obtained via different processing methods and evaluated of their morphology, crystalline structure and thermal property. All silk fillers showed different degrees of improvement on printability in terms of ink rheology and printing shape fidelity. Different silk fillers led to different scaffold surface morphology and different roughness, while all reduced the contact angle compared to pure chitosan. Similar reinforcements were observed on compressive modulus, while oscillatory gel strength reinforcement was found to be positively correlated to the filler aspect ratio. Addition of silk introduced no cytotoxicity for that all scaffolds supported a steady cell growth using human fibroblasts. Meanwhile different cellular behaviours were observed on different scaffold surfaces, which can possibly intriguer specific application on soft tissue engineering.
Regenerated silk fibroin using protic ionic liquidssolvents: towards an all-ionic-liquid process for producing silk with tunable properties
Publisher: Royal Society of Chemistry (RSC)
Date: 2012
DOI: 10.1039/C2CC17143K
Abstract: We have shown that protic ionic liquids, pILs, are effective coagulation solvents for the regenerated of silk fibroin, RSF. We show that the choice of pIL has a dramatic effect on the composition of the RSF. Additionally the use of pILs as the coagulator eliminates the need for volatile organic solvents in silk processing.
Ultra-fine silk powder preparation through rotary and ball milling
Publisher: Elsevier BV
Date: 06-2008
Glycerol-plasticised silk membranes made using formic acid are ductile, transparent and degradation-resistant
Publisher: Elsevier BV
Date: 11-2017
Enhanced formation of bioactive and strong silk–bioglass hybrid materials through organic–inorganic mutual molecular nucleation induction and templating
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2NR03417D
Abstract: Silk fibroin and bioglass coassemble to form a hybrid structure that is bioactive and mechanically strong.
Photoprotection by silk cocoons
Publisher: American Chemical Society (ACS)
Date: 19-09-2013
DOI: 10.1021/BM401023H
Abstract: A silk cocoon protects a silkworm during its pupal stage from various threats. We systematically investigated the role of fiber, sericin, and embedded crystals in the UV protection of a silk cocoon. Diffuse reflectance and UV absorbance were measured and free radicals generated during exposure to UV radiation were quantified using photoinduced chemiluminescence (PICL). We identified the response to both UV-A and UV-B radiations by silk materials and found that sericin was primarily responsible for UV-A absorption. When sericin was removed, the photoinduced chemiluminescence intensity increased significantly, indicating higher UV-A-induced reactions of cocoons in the absence of sericin. There is progressively higher sericin content toward the outer part of the cocoon shell that allows an effective shield to pupae from UV radiation and resists photodegradation of silk fibers. The study will inspire development of advanced organic photoprotective materials and designing silk-based, free-radical-scavenging antioxidants.
Structure-property relationships of elementary bamboo fibers
Publisher: Springer Science and Business Media LLC
Date: 05-10-2016
Mechanical improvements to reinforced porous silk scaffolds
Publisher: Wiley
Date: 25-07-2011
DOI: 10.1002/JBM.A.33158
Functionality of nano and 3D-microhierarchical TiO2 particles as coagulants for sericin extraction from the silk degumming wastewater
Publisher: Elsevier BV
Date: 10-2016
Communication strategies to promote the uptake of childhood vaccination in Nigeria: a systematic map
Publisher: Informa UK Limited
Date: 12-02-2016
DOI: 10.3402/GHA.V9.30337
Abstract: Effective communication is a critical component in ensuring that children are fully vaccinated. Although numerous communication interventions have been proposed and implemented in various parts of Nigeria, the range of communication strategies used has not yet been mapped systematically. This study forms part of the 'Communicate to vaccinate' (COMMVAC) project, an initiative aimed at building research evidence for improving communication with parents and communities about childhood vaccinations in low- and middle-income countries. This study aims to: 1) identify the communication strategies used in two states in Nigeria 2) map these strategies against the existing COMMVAC taxonomy, a global taxonomy of vaccination communication interventions 3) create a specific Nigerian country map of interventions organised by purpose and target and 4) analyse gaps between the COMMVAC taxonomy and the Nigerian map. We conducted the study in two Nigerian states: Bauchi State in Northern Nigeria and Cross River State in Southern Nigeria. We identified vaccination communication interventions through interviews carried out among purposively selected stakeholders in the health services and relevant agencies involved in vaccination information delivery through observations and through relevant documents. We used the COMMVAC taxonomy to organise the interventions we identified based on the intended purpose of the communication and the group to which the intervention was targeted. The Nigerian map revealed that most of the communication strategies identified aimed to inform and educate and remind or recall. Few aimed to teach skills, enhance community ownership, and enable communication. We did not identify any intervention that aimed to provide support or facilitate decision-making. Many interventions had more than one purpose. The main targets for most interventions were caregivers and community members, with few interventions directed at health workers. Most interventions identified were used in the context of c aigns rather than routine immunisation programmes. The identification and development of the Nigerian vaccination communication interventions map could assist programme managers to identify gaps in vaccination communication. The map may be a useful tool as part of efforts to address vaccine hesitancy and improve vaccination coverage in Nigeria and similar settings.
Methods for Silk Property Analyses across Structural Hierarchies and Scales
Publisher: MDPI AG
Date: 24-02-2023
DOI: 10.3390/MOLECULES28052120
Abstract: Silk from silkworms and spiders is an exceptionally important natural material, inspiring a range of new products and applications due to its high strength, elasticity, and toughness at low density, as well as its unique conductive and optical properties. Transgenic and recombinant technologies offer great promise for the scaled-up production of new silkworm- and spider-silk-inspired fibres. However, despite considerable effort, producing an artificial silk that recaptures the physico-chemical properties of naturally spun silk has thus far proven elusive. The mechanical, biochemical, and other properties of pre-and post-development fibres accordingly should be determined across scales and structural hierarchies whenever feasible. We have herein reviewed and made recommendations on some of those practices for measuring the bulk fibre properties skin-core structures and the primary, secondary, and tertiary structures of silk proteins and the properties of dopes and their proteins. We thereupon examine emerging methodologies and make assessments on how they might be utilized to realize the goal of developing high quality bio-inspired fibres.
Toughening Wet-Spun Silk Fibers by Silk Nanofiber Templating
Publisher: Wiley
Date: 14-01-2022
Abstract: Regenerated silk fibers typically fall short of silkworm cocoon fibers in mechanical properties due to reduced fiber crystal structure and alignment. One approach to address this has been to employ inorganic materials as reinforcing agents. The present study avoids the need for synthetic additives, demonstrating the first use of exfoliated silk nanofibers to control silk solution crystallization, resulting in all‐silk pseudocomposite fibers with remarkable mechanical properties. Incorporating only 0.06 wt% silk nanofibers led to a ≈44% increase in tensile strength (over 600 MPa) and ≈33% increase in toughness (over 200 kJ kg −1 ) compared with fibers without silk nanofibers. These remarkable properties can be attributed to nanofiber crystal seeding in conjunction with fiber draw. The crystallinity nearly doubled from ≈17% for fiber spun from pure silk solution to ≈30% for the silk nanofiber reinforced s le. The latter fiber also shows a high degree of crystal orientation with a Herman's orientation factor of 0.93, a value which approaches that of natural degummed B. mori silk cocoon fiber (0.96). This study provides a strong foundation to guide the development of simple, eco‐friendly methods to spin regenerated silk with excellent properties and a hierarchical structure that mimics natural silk.
Mechanical properties and structure of silkworm cocoons: A comparative study of Bombyx mori, Antheraea assamensis, Antheraea pernyi and Antheraea mylitta silkworm cocoons
Publisher: Elsevier BV
Date: 08-2013
DOI: 10.1016/J.MSEC.2013.03.051
Abstract: As a protective shell against environmental damage and attack by natural predators, the silkworm cocoon has outstanding mechanical properties. In particular, this multilayer non-woven composite structure can be exceptionally tough to enhance the chance of survival for silkworms while supporting their metabolic activity. Peel, out-of-plane compression and nano-indentation tests and micro-structure analysis were performed on four types of silkworm cocoon walls (domesticated Bombyx mori, semi-domesticated Antheraea assamensis and wild Antheraea pernyi and Antheraea mylitta silkworm cocoons) to understand the structure and mechanical property relationships. The wild silkworm cocoons were shown to be uniquely tough composite structures. The maximum work-of-fracture for the wild cocoons (A. pernyi and A. mylitta) was approximately 1000 J/m(2), which was almost 10 times the value for the domesticated cocoon (Bombyx mori) and 3~4 times the value for the semi-domesticated cocoon (A. assamensis). Calcium oxalate crystals were found to deposit on the outer surfaces of the semi-domesticated and wild cocoons. They did not show influence in enhancing the interlaminar adhesion between cocoon layers but exhibited much higher hardness than the cocoon pelades.
Ultrafine wool powders and their bulk properties
Publisher: Elsevier BV
Date: 07-2012
Molecular weight and secondary structure change in eri silk during alkali degumming and powdering
Publisher: Wiley
Date: 18-08-2010
DOI: 10.1002/APP.31981
Human Resources Practices in Non-profit Organizations: Evidence from the Kingdom of Saudi Arabia
Publisher: Amazonia Investiga
Date: 30-08-2022
Abstract: Non-profit organizations (NPOs) are essential to the economic planning process in Saudi Arabia. This study examines the Human Resource (HR) practices of Saudi Arabian non-profit organizations. It is based on a primary survey administered to 201 employees of the four types of existing non-profit organizations (NPOs) in Saudi Arabia (Qur'an Memorization Society, Dawah Society, Specialized Society, and Development Committee) using a structured questionnaire. The questionnaire was intended for the eight existing HR practices: work design, HR planning, polarization, selection, training and development, motivation, performance evaluation, and job satisfaction. The ANOVA and Pearson correlation tests were performed on the eight segments of the HR instruments to investigate the perspectives of HR professionals in the NPO sector. The findings of the study indicate that the HR practices are moderated by the gender, age, education, and years of experience of the employees. The work design has the highest awareness among the employees, with a mean of 4.05, while job satisfaction has the lowest awareness, with a mean of 3.18 on a 5-point scale. A correlation between HR practices shows that work design improves performance evaluation, polarization affects HR planning, and training and development influence performance evaluation.
Using the COMMVAC taxonomy to map vaccination communication interventions in Mozambique
Publisher: Informa UK Limited
Date: 2017
Grafts in myringoplasty: utilizing a silk fibroin scaffold as a novel device
Publisher: Informa UK Limited
Date: 11-2009
DOI: 10.1586/ERD.09.47
Abstract: Chronic perforations of the eardrum or tympanic membrane represent a significant source of morbidity worldwide. Myringoplasty is the operative repair of a perforated tympanic membrane and is a procedure commonly performed by otolaryngologists. Its purpose is to close the tympanic membrane, improve hearing and limit patient susceptibility to middle ear infections. The success rates of the different surgical techniques used to perform a myringoplasty, and the optimal graft materials to achieve complete closure and restore hearing, vary significantly in the literature. A number of autologous tissues, homografts and synthetic materials are described as graft options. With the advent and development of tissue engineering in the last decade, a number of biomaterials have been studied and attempts have been made to mimic biological functions with these materials. Fibroin, a core structural protein in silk from silkworms, has been widely studied with biomedical applications in mind. Several cell types, including keratinocytes, have grown on silk biomaterials, and scaffolds manufactured from silk have successfully been used in wound healing and for tissue engineering purposes. This review focuses on the current available grafts for myringoplasty and their limitations, and examines the biomechanical properties of silk, assessing the potential benefits of a silk fibroin scaffold as a novel device for use as a graft in myringoplasty surgery.
Outcomes mapping study for childhood vaccination communication: too few concepts were measured in too many ways
Publisher: Elsevier BV
Date: 04-2016
DOI: 10.1016/J.JCLINEPI.2015.10.003
Abstract: The objectives of this article are to (1) comprehensively catalog outcomes measured in trials of childhood vaccination communication interventions and (2) analyze patterns and trends in outcome selection. To achieve these objectives, we developed a Trial Outcomes Map for vaccination communication. We searched the Cochrane Central Register of Controlled Trials for trials of childhood vaccination communication interventions, extracting verbatim all outcome information from included trials. Through thematic grouping, we categorized outcomes based on conceptual similarities, forming a Trial Outcomes Map. We identified 112 relevant trials containing 209 outcomes. Thematic analysis revealed three overarching Outcome Categories: consumer-, vaccination-, and health system-related outcomes. These categories contain 21 Outcome Types (eg, "knowledge," "cost"), measured using 66 different Outcome Variables. Vaccination outcomes were measured most frequently and health system-related outcomes least frequently. Consumer outcomes are increasingly measured in more recent trials. The number of measures used for the same outcomes complicates data synthesis and interpretation. Despite recent trends toward including consumer outcomes, intermediate outcome measurement is lacking, h ering understanding of how and why vaccination communication interventions do or do not work. This Map may improve outcome consistency in future trials and will contribute to a forthcoming core outcome set.
Related Organisations
International Union For Health Promotion And Education
Location: France
University Of California, San Francisco
Location: United States of America
Related Funding Activities
Discovery Projects - Grant ID: DP120100139
Start Date: 2012
End Date: 12-2015
Amount: $310,000.00
Funder: Australian Research Council
View Funded ActivityLinkage Projects - Grant ID: LP200301442
Start Date: 04-2022
End Date: 03-2025
Amount: $356,280.00
Funder: Australian Research Council
View Funded ActivityIndustrial Transformation Research Hubs - Grant ID: IH210100023
Start Date: 09-2022
End Date: 09-2027
Amount: $5,000,000.00
Funder: Australian Research Council
View Funded ActivityLinkage Projects - Grant ID: LP140100287
Start Date: 02-2015
End Date: 12-2018
Amount: $470,491.00
Funder: Australian Research Council
View Funded ActivityLinkage Projects - Grant ID: LP110200547
Start Date: 02-2012
End Date: 12-2015
Amount: $415,000.00
Funder: Australian Research Council
View Funded ActivityIndustrial Transformation Research Hubs - Grant ID: IH140100018
Start Date: 05-2016
End Date: 05-2021
Amount: $4,711,583.00
Funder: Australian Research Council
View Funded ActivityIndustrial Transformation Training Centres - Grant ID: IC190100034
Start Date: 12-2020
End Date: 12-2025
Amount: $3,574,272.00
Funder: Australian Research Council
View Funded Activity