ORCID Profile
0000-0002-9442-0385
Current Organisation
Universidade Estadual Paulista Júlio de Mesquita Filho
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Publisher: MDPI AG
Date: 24-09-2021
Abstract: Muscle weakness is a secondary motor symptom of Parkinson’s disease (PD), especially in the subtype characterized by postural instability and gait difficulty (PIGD). Since the PIGD subtype also presents worse bradykinesia, we hypothesized that it also shows a decreased rate of force development, which is linked to an increased risk of falling in PD. Therefore, we investigated the effects of PD and PD subtypes on a force production profile and correlated the force production outcomes with clinical symptoms for each PD subtype. We assessed three groups of participants: 14 healthy older adults (OA), 10 people with PD composing the PIGD group, and 14 people with PD composing the tremor-dominant group. Three knee extension maximum voluntary isometric contractions were performed in a leg extension machine equipped with a load cell to assess the force production. The outcome measures were: peak force and rate of force development (RFD) at 50 ms (RFD50), 100 ms (RFD100), and 200 ms (RFD200). We observed lower peak force, RFD50, RFD100, and RFD200 in people with PD, regardless of subtypes, compared with the OA group (p 0.05 for all comparisons). Together, our results indicated that PD affects the capacity to produce maximal and rapid force. Therefore, future interventions should consider rehabilitation programs for people with PD based on muscle power and fast-force production, and consequently reduce the likelihood of people with PD falling from balance-related events, such as from an unsuccessful attempt to avoid a tripping hazard or a poor and slower stepping response.
Publisher: Informa UK Limited
Date: 02-04-2016
DOI: 10.1080/08990220.2016.1182015
Abstract: We tested local vibration effects during upright standing considering: (i) the orientation of vibratory devices in relation to muscle fibres (ii) the muscle region stimulated and (iii) the number of stimulation spots. Results showed a higher balance disturbance with vibration devices oriented parallel to triceps surae muscle fibres. The single stimulation of the proximal region of the tibialis anterior muscle belly induces the same proprioceptive disturbance as stimulating multiple regions simultaneously.
Publisher: FapUNIFESP (SciELO)
Date: 07-2015
Publisher: Universidade de Sao Paulo, Agencia USP de Gestao da Informacao Academica (AGUIA)
Date: 30-11-2018
DOI: 10.11606/ISSN.2238-6149.V29I3P223-229
Abstract: A doença de Parkinson (DP) é caracterizada pelo início assimétrico de sintomas motores e compromete a destreza manual. Espera-se que pacientes com o lado de início da doença preferido comprometido consigam manter bom desempenho com o lado mais afetado (LMA) no teste de destreza manual decorrente da experiência motora ao longo da vida. O objetivo do estudo foi verificar a interferência da coincidência entre o lado de início da doença e preferência manual no desempenho da destreza manual, LMA e lado menos afetado, em pacientes com DP. Os pacientes foram distribuídos conforme o lado de início: Grupo Coincidente (lado preferido acometido) e Grupo Não Coincidente (lado não preferido acometido). A destreza manual foi avaliada pelo teste Annett Pegboard adaptado. A análise estatística ANOVA de dois fatores (grupo x lado), medidas repetidas no último fator, revelou que o Grupo Não Coincidente dispendeu maior tempo para completar o teste com o LMA (p=0,001), enquanto, o Grupo Coincidente dispendeu o mesmo tempo com ambos os lados, indicando que pacientes nos estágios iniciais e com início da doença pelo lado preferido perdem a proficiência manual. Sugere-se que intervenções para melhorar as habilidades manuais sejam aplicadas desde o diagnóstico da doença, principalmente em pacientes com o lado preferido acometido.
Publisher: Termedia Sp. z.o.o.
Date: 2015
Abstract: Purpose. Previous studies have studied the role of proprioception on the setting of anticipatory postural adjustments (APA) during gait initiation. However, these studies did not investigate the role of proprioception in the sagittal APA setting. We aimed to investigate the role of proprioception manipulation to induce APA sagittal adaptations on gait initiation. Methods. Fourteen healthy adults performed gait initiation without, and with, vibration applied before movement onset, and during movement. In addition, the effects of two different vibration frequencies (80 and 120Hz) were tested. Vibration was applied bilaterally on the tibialis anterior, rectus femoris and trapezius superior. The first step characteristics, ground reaction forces and CoP behaviour were assessed. Results. Vibration improved gait initiation performance regardless of the moment it was applied. CoP velocity during the initial phase of APA was increased by vibration only when it was applied before movement. When vibration was applied to disturb the movement, no effects on the CoP behaviour were observed. Manipulation of vibration frequency had no effects. Conclusions. Rather than proprioception manipulation, the results suggest that post-vibratory effects and attentional mechanisms were responsible for our results. Taken together, the results show that sagittal APA setting is robust to proprioception manipulation.
Publisher: SAGE Publications
Date: 12-2015
Abstract: This study assesses the association between disease onset side (dominant or non-dominant) and vision on postural control of Parkinson's disease patients. Patient volunteers composed two groups, according to the onset side affected: Dominant group ( n = 9 M age = 66.1 yr., SD = 7.2 6 women, 3 men) and Non-dominant group ( n = 9 M age = 67.4yr., SD = 6.4 6 women, 3 men). The groups' postural control was assessed by posturography during quiet upright stance in two conditions, Eyes open and Eyes closed. Two-way analyses of variance (ANOVAs group × condition) with repeated measures for the second factor assessed the differences associated with affected hemibody and vision on postural control. Analyses indicated that patients with the dominant side affected also presented significantly greater variation in center of pressure than those with the non-dominant side affected, mainly in the Eyes closed condition. The results demonstrate a higher reliance on vision in the dominant side, possibly to compensate somatosensory system impairments. These results also highlight the importance of analyzing the hemibody affected by the disease when postural control is assessed in this population.
Location: Brazil
No related grants have been discovered for Marcelo Pinto Pereira.