Vanessa Finney

Chains of Custody, Oceans of Instability: The Precarious Logistics of the Natural History Trade

Publisher: Project MUSE

Date: 03-2022

DOI: 10.1353/JWH.2022.0003

Animating the hand of the scientist: women colourists at the Australian Museum in the early twentieth century

Publisher: Informa UK Limited

Date: 03-07-2019

DOI: 10.1080/17460654.2019.1649349

Quantitative flow ratio to predict long-term coronary artery bypass graft patency in patients with left main coronary artery disease

Publisher: Springer Science and Business Media LLC

Date: 28-08-2022

DOI: 10.1007/S10554-022-02699-5

Abstract: Fractional flow reserve (FFR) has been demonstrated in some studies to predict long-term coronary artery bypass graft (CABG) patency. Quantitative flow ratio (QFR) is an emerging technology which may predict FFR. In this study, we hypothesised that QFR would predict long-term CABG patency and that QFR would offer superior diagnostic performance to quantitative coronary angiography (QCA) and intravascular ultrasound (IVUS). A prospective study was performed on patients with left main coronary artery disease who were undergoing CABG. QFR, QCA and IVUS assessment was performed. Follow-up computed tomography coronary angiography and invasive coronary angiography was undertaken to assess graft patency. A total of 22 patients, comprising of 65 vessels were included in the analysis. At a median follow-up of 3.6 years post CABG (interquartile range, 2.3 to 4.8 years), 12 grafts (18.4%) were occluded. QFR was not statistically significantly higher in occluded grafts (0.81 ± 0.19 vs. 0.69 ± 0.21 P = 0.08). QFR demonstrated a discriminatory power to predict graft occlusion (area under the receiver operating characteristic curve, 0.70 95% confidence interval [CI], 0.52 to 0.88 P = 0.03). At long-term follow-up, the risk of graft occlusion was higher in vessels with a QFR 0.80 (58.6% vs. 17.0% hazard ratio, 3.89 95% CI, 1.05 to 14.42 P = 0.03 by log-rank test). QCA (minimum lumen diameter, lesion length, diameter stenosis) and IVUS (minimum lumen area, minimum lumen diameter, diameter stenosis) parameters were not predictive of long-term graft patency. QFR may predict long-term graft patency in patients undergoing CABG.

University Of Sydney

Location: Australia

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Australian Museum

Location: Australia

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Reconstructing Museum Specimen Data Through The Pathways Of Global Commerce

Start Date: 2017

End Date: 2019

Funder: Australian Research Council

Linkage Projects - Grant ID: LP160101761

Start Date: 01-2018

End Date: 09-2023

Amount: $403,060.00

Funder: Australian Research Council