ORCID Profile
0000-0002-7930-2145
Current Organisation
University of Sydney
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Research Topics
In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Top 5 Research Topics
ANZSRC Field of Research (FoR)
Numerical Modelling and Mechanical Characterisation | Mechanical Engineering | Biomedical Engineering | Biomechanical Engineering | Biomaterials | Biomechanical Engineering | Biomaterials | Composite Materials | Cad/Cam Systems | Aerospace Engineering | Interdisciplinary Engineering Not Elsewhere Classified | Structural Engineering | Aerospace Structures | Mechanical engineering | Automotive Safety Engineering | Zoology | Functional Materials | Geomechanics and Resources Geotechnical Engineering | Resources Engineering and Extractive Metallurgy | Materials Engineering | Animal Anatomy And Histology | Petroleum and Reservoir Engineering | Biomedical Engineering Not Elsewhere Classified | Interdisciplinary Engineering | Composite and Hybrid Materials | Regenerative Medicine (incl. Stem Cells and Tissue Engineering) | Biomechanics | Medical Devices | Solid mechanics | Numerical modelling and mechanical characterisation | Orthopaedics | Computational Heat Transfer | Computational Fluid Dynamics | Solid Mechanics | Condensed Matter Characterisation Technique Development | Numerical Analysis
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in Engineering | Skeletal system and disorders (incl. arthritis) | Biological sciences | Other | Metals (composites, coatings, bonding, etc.) | Dental health | Expanding Knowledge in the Biological Sciences | Skeletal System and Disorders (incl. Arthritis) | Health related to ageing | Oro-Dental Disorders | Air transport | Aerospace equipment | Space transport | Other | Machined Metal Products | Cardiovascular System and Diseases | Hearing, vision, speech and their disorders | Structural Metal Products | Ceramics | Road Safety | Structural metal products | Medical instrumentation | Surgical methods and procedures | Expanding Knowledge in Technology | Solar-Thermal Electric Energy | Polymeric materials (e.g. paints) | Expanding Knowledge in the Earth Sciences | Dental Health | Medical Instruments | Preventive medicine |
Related Links
Publications
Shape and topology design for heat conduction by Evolutionary Structural Optimization
Publisher: Elsevier BV
Date: 09-1999
Multiobjective topology optimization for finite periodic structures
Publisher: Elsevier BV
Date: 06-2010
Characterization of tissue scaffolds for time-dependent biotransport criteria – a novel computational procedure
Publisher: Informa UK Limited
Date: 30-12-2015
DOI: 10.1080/10255842.2015.1124268
Abstract: This study aims to establish a new computational framework that allows modeling transient oxygen diffusion in tissue scaffolds more efficiently. It has been well known that the survival of cells strongly relies on continuous oxygen/nutrient supply and metabolite removal. With optimal design in scaffold architecture, its ability to sustain long distance oxygen supply could be improved considerably. In this study, finite element based homogenization procedure is first used to characterize the initial effective biotransport properties in silico. These initial properties are proper indicators to prediction of the on-going performance of tissue scaffolds over time. The transient model by adopting an edge-based smoothed finite element method with combination of mass-redistributed method is then established to more efficiently simulate the transient oxygen transfer process in tissue scaffolds. The proposed new method allows large time steps to model the oxygen diffusion process without losing numerical accuracy, thereby enhancing the computational efficiency significantly, in particular for the design optimization problems which typically require numerous analysis iterations. A number of different scaffold designs are examined either under net diffusion without cell seeding, or under cellular oxygen/nutrient uptake with or without considering cell viability. The association between the homogenized effective diffusivity of net scaffold microstructures and corresponding transient diffusion and time-dependent cellular activities is ulged. This study provides some insights into scaffold design.
Topographical design of stiffener layout for plates against blast loading using a modified ant colony optimization algorithm
Publisher: Springer Science and Business Media LLC
Date: 18-12-2018
A comparative study on thin-walled structures with functionally graded thickness (FGT) and tapered tubes withstanding oblique impact loading
Publisher: Elsevier BV
Date: 03-2015
Evolutionary shape optimization for stress minimization
Publisher: Elsevier BV
Date: 11-1999
An evolutionary approach to elastic contact optimization of frame structures
Publisher: Elsevier BV
Date: 11-2003
Mechanical benefits of conservative restoration for dental fissure caries
Publisher: Elsevier BV
Date: 2016
DOI: 10.1016/J.JMBBM.2015.08.010
Abstract: The principle of minimal intervention dentistry (MID) is to limit removal of carious tooth tissue while maximizing its repair and survival potential. The objective of this study is to explore the fracture resistance of a permanent molar tooth with a fissure carious lesion along with three clinical restoration procedures, namely one traditional and two conservative approaches, based upon MID. The traditional restoration employs extensive surgical removal of enamel and dentine about the cavity to eliminate potential risk of further caries development, while conservative method #1 removes significantly less enamel and infected dentine, and conservative method #2 only restores the overhanging enamel above the cavity and leaves the infected and affected dentine as it was. An extended finite element method (XFEM) is adopted here to analyze the fracture behaviors of both two-dimensional (2D) and three-dimensional (3D) modeling of these four different scenarios. It was found that the two conservative methods exhibited better fracture resistance than the traditional restorative method. Although conservative method #2 has less fracture resistance than method #1, it had significantly superior fracture resistance compared to other restorations. More important, after cavity sealing it may potentially enhance the opportunity for remineralization and improved loading bearing capacity and fracture resistance.
Engineering Pre-vascularized Scaffolds for Bone Regeneration
Publisher: Springer International Publishing
Date: 2015
DOI: 10.1007/978-3-319-22345-2_5
Abstract: Survival of functional tissue constructs of clinically relevant size depends on the formation of an organized and uniformly distributed network of blood vessels and capillaries. The lack of such vasculature leads to spatio-temporal gradients in oxygen, nutrients and accumulation of waste products inside engineered tissue constructs resulting in negative biological events at the core of the scaffold. Unavailability of a well-defined vasculature also results in ineffective integration of scaffolds to the host vasculature upon implantation. Arguably, one of the greatest challenges in engineering clinically relevant bone substitutes, therefore, has been the development of vascularized bone scaffolds. Various approaches ranging from peptide and growth factor functionalized biomaterials to hyper-porous scaffolds have been proposed to address this problem with reasonable success. An emerging alternative to address this challenge has been the fabrication of pre-vascularized scaffolds by taking advantage of biomanufacturing techniques, such as soft- and photo-lithography or 3D bioprinting, and cell-based approaches, where functional capillaries are engineered in cell-laden scaffolds prior to implantation. These strategies seek to engineer pre-vascularized tissues in vitro, allowing for improved anastomosis with the host vasculature upon implantation, while also improving cell viability and tissue development in vitro. This book chapter provides an overview of recent methods to engineer pre-vascularized scaffolds for bone regeneration. We first review the development of functional blood capillaries in bony structures and discuss controlled delivery of growth factors, co-culture systems, and on-chip studies to engineer vascularized cell-laden biomaterials. Lastly, we review recent studies using microfabrication techniques and 3D printing to engineer pre-vascularized scaffolds for bone tissue engineering.
Medical image classification with convolutional neural network
Publisher: IEEE
Date: 12-2014
Crashworthiness analysis and optimization of fourier varying section tubes
Publisher: Elsevier BV
Date: 06-2017
Comparative study on metal/CFRP hybrid structures under static and dynamic loading
Publisher: Elsevier BV
Date: 07-2020
On crashworthiness design of hybrid metal-composite structures
Publisher: Elsevier BV
Date: 04-2020
An evolutionary shape optimization procedure for contact problems in mechanical designs
Publisher: SAGE Publications
Date: 04-2003
DOI: 10.1243/095440603321509711
Abstract: The finite element method (FEM) has been extensively applied to explore contact stress distributions in multi-body mechanical systems. Uneven contact stresses are often one of the main concerns of mechanical design engineers. By adopting the evolutionary structural optimization (ESO) concepts, this paper presents a non-gradient procedure for gradual shape redesign of prescribed contact interfaces. In this method, interfacial gaps are considered as design variables and contact stress deviations over design interfaces are set as the objective function. To deal with multiple contact region problems, two different design objectives, namely an in idual criteria and a unified criteria, are formulated respectively. Several practical ex les show that this method is effective for design problems consisting of single- or multiple-contact regions in mechanical systems, in which a uniform contact stress pattern is the desired optimality criterion.
Correction to: Phase field fracture in elasto-plastic solids: a length-scale insensitive model for quasi-brittle materials
Publisher: Springer Science and Business Media LLC
Date: 22-04-2021
Computational and clinical investigation on the role of mechanical vibration on orthodontic tooth movement
Publisher: Elsevier BV
Date: 07-2017
DOI: 10.1016/J.JBIOMECH.2017.06.012
Abstract: The aim of this study is to investigate the biomechanics for orthodontic tooth movement (OTM) subjected to concurrent single-tooth vibration (50Hz) with conventional orthodontic force application, via a clinical study and computational simulation. Thirteen patients were recruited in the clinical study, which involved distal retraction of maxillary canines with 1.5N (150g) force for 12weeks. In a split mouth study, vibration and non-vibration sides were randomly assigned to each subject. Vibration of 50Hz, of approximately 0.2N (20g) of magnitude, was applied on the buccal surface of maxillary canine for the vibration group. A mode-based steady-state dynamic finite element analysis (FEA) was conducted based on an anatomically detailed model, complying with the clinical protocol. Both the amounts of space closure and canine distalization of the vibration group were significantly higher than those of the control group, as measured intra-orally or on models (p<0.05). Therefore it is indicated that a 50Hz and 20g single-tooth vibration can accelerate maxillary canine retraction. The volume-average hydrostatic stress (VHS) in the periodontal ligament (PDL) was computationally calculated to be higher with vibration compared with the control group for maxillary teeth and for both linguo-buccal and mesial-distal directions. An increase in vibratory frequency further lified the PDL response before reaching a local natural frequency. An lification of PDL response was also shown to be induced by vibration based on computational simulation. The vibration-enhanced OTM can be described by mild, vigorous and diminishing zones among which the mild zone is considered to be clinically beneficial.
Computer-aided design and fabrication of bio-mimetic materials and scaffold micro-structures
Publisher: Trans Tech Publications, Ltd.
Date: 02-2011
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMR.213.628
Abstract: Computer-aided design (CAD) has proven effective in enabling novel approaches for tissue engineering applications. This paper demonstrates the applicability of various mathematical methods to design and fabricate bio-mimetic materials via two illustrative ex les. Firstly, CAD models of cellular biomaterials that mimic the micro-structure of cuttlefish bone are designed based on the principles of the homogenization method. Secondly, a three-dimensional bi-objective topology optimization approach based upon the inverse homogenization method is used to design scaffold micro-structures with tailored effective stiffness and permeability properties. Consequently, solid free-form fabrication is used to fabricate such cellular bio-mimetic materials, which show a great potential in tissue engineering applications.
On crushing responses of filament winding CFRP/aluminum and GFRP/CFRP/aluminum hybrid structures
Publisher: Elsevier BV
Date: 11-2020
Design for cost performance of crashworthy structures made of high strength steel
Publisher: Elsevier BV
Date: 05-2019
On the structural parameters of honeycomb-core sandwich panels against low-velocity impact
Publisher: Elsevier BV
Date: 07-2021
Gold nanoparticle based photothermal therapy: Development and application for effective cancer treatment
Publisher: Elsevier BV
Date: 12-2019
Design of periodic microstructural materials by using evolutionary structural optimization method
Publisher: Trans Tech Publications Ltd.
Date: 09-02-2008
A design procedure for electric inductive capacitive resonators with negative permittivity
Publisher: Trans Tech Publications, Ltd.
Date: 10-2014
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMM.448-453.2199
Abstract: Permittivity signifies a key component to metamaterial which can achieve negative index of refraction, but it has not been sufficiently addressed in computational design. This paper aims to attain negative permittivity through a topology optimization approach and provides an ex le equivalent to electric inductive-capacitive resonator. Similar to split ring resonator, this locally self-contained (without the demand for inter-cell connection) resonator allows keeping bulk electromagnetic properties homogeneously, facilitating mass fabrication, and realizing single s ling test.
Bending characteristics of top-hat structures through tailor rolled blank (TRB) process
Publisher: Elsevier BV
Date: 02-2018
Architectural Design of 3D Printed Scaffolds Controls the Volume and Functionality of Newly Formed Bone
Publisher: Wiley
Date: 07-12-2018
Abstract: The successful regeneration of functional bone tissue in critical-size defects remains a significant clinical challenge. To address this challenge, synthetic bone scaffolds are widely developed, but remarkably few are translated to the clinic due to poor performance in vivo. Here, it is demonstrated how architectural design of 3D printed scaffolds can improve in vivo outcomes. Ceramic scaffolds with different pore sizes and permeabilities, but with similar porosity and interconnectivity, are implanted in rabbit calvaria for 12 weeks, and then the explants are harvested for microcomputed tomography evaluation of the volume and functionality of newly formed bone. The results indicate that scaffold pores should be larger than 390 µm with an upper limit of 590 µm to enhance bone formation. It is also demonstrated that a bimodal pore topology-alternating large and small pores-enhances the volume and functionality of new bone substantially. Moreover, bone formation results indicate that stiffness of new bone is highly influenced by the scaffold's permeability in the direction concerned. This study demonstrates that manipulating pore size and permeability in a 3D printed scaffold architecture provides a useful strategy for enhancing bone regeneration outcomes.
Nondeterministic optimization of tapered sandwich column for crashworthiness
Publisher: Elsevier BV
Date: 2018
Microstructural heterogeneity of the collagenous network in the loaded and unloaded periodontal ligament and its biomechanical implications
Publisher: Elsevier BV
Date: 09-2021
Experimental study on residual properties of carbon fibre reinforced plastic (CFRP) and aluminum single-lap adhesive joints at different strain rates after transverse pre-impact
Publisher: Elsevier BV
Date: 09-2019
On functionally graded composite structures for crashworthiness
Publisher: Elsevier BV
Date: 11-2015
Directed glia‐assisted angiogenesis in a mature neurosensory structure: Pericytes mediate an adaptive response in human dental pulp that maintains blood‐barrier function
Publisher: Wiley
Date: 10-2012
DOI: 10.1002/CNE.23162
Abstract: The specialized tightly controlled microcirculation of craniofacial neurosensory organs is an essential evolutionary adaptation and yet a dilemma where angiogenic remodeling occurs. Despite extreme plasticity of neurosensory structures, the capacity to reconcile barrier phenotype of the microcirculation with an angiogenic cascade is not known. Here we provide primary evidence for such a response in an elemental neurosensory structure, human dental pulp, following chronic carious insult. In response to hypoxic challenge neurosensory odontoblasts express hypoxia-inducible factor-1α and notch-1. Associated radial rearrangement of astrocyte-like telacytes that communicate through a cell-poor zone with the microvasculature is observed. Activated pericytes characterized by expression of α-smooth muscle actin are located adjacent to the telacyte attachment to the vasculature. In this location, endothelial expression of sonic hedgehog parallels expression of notch-1 by pericytes. The angiogenic response is initiated by pericyte contraction and altered endothelial polarity and proliferation leading to intussusception of endothelial cells and extensive remodeling of basement membrane with upregulation of laminin-8 and laminin-5. These responses guide intravascular loop formation that maintains both intact basement membrane and tight junctions. This initial phase is followed by formation of anastomoses that enhance the hemodynamic capacity of the intravascular loops. The formation of anastomoses is mediated by extension of cytonemes from pericytes guided by MHC-II(+)/CD-163(+) microglia aligned with the telacytes. The cytonemes seek out pericytes on adjacent intravascular loops to initiate migration of endothelial cells. These findings support a new paradigm for understanding angiogenic capacity of neurosensory structures and aberrations of this response manifest as neurovasculopathies.
Finite periodic topology optimization with oriented unit-cells
Publisher: Springer Science and Business Media LLC
Date: 19-08-2021
Crashworthiness optimization of new thin-walled cellular configurations
Publisher: Emerald
Date: 07-2014
Abstract: – The purpose of this paper is to optimize a new thin-walled cellular configurations with crashworthiness criteria, so as to improve the crashworthiness of components of a vehicle body. – ANSYS Parametric Design Language is used to create the parameterized models so that the design variables can be changed conveniently. Moreover, the surrogate technique, namely response surface method, is adopted for fitting objective and constraint functions. The factorial design and D-optimal criterion are employed to screen active parameters for constructing the response functions of the specific energy absorption and the peak crushing force. Finally, sequential quadratic programming-NLPQL is utilized to solve the design optimization problem of the new cellular configurations filled with multi-cell circular tubes under the axial crushing loading. – Two kinds of distribution modes of the cellular configurations are first investigated, which are in an orthogonal way and in a diamond fashion. After comparing the optimized configurations of the rectangular distribution with the annular distribution of the multi-cell fillers, it is found that the orthogonal way seems better in the aspects of crashworthiness than the diamond fashion. – The two new thin-walled cellular configuration are studied and optimized with the crashworthiness criteria. Study on the new cellular configurations is very valuable for improving the crashworthiness of components of a vehicle body. Meanwhile, the factorial design and the factor screening are adopted in the process of the crashworthiness optimization of the new thin-walled cellular configurations.
Mechanical responses to orthodontic loading: A 3-dimensional finite element multi-tooth model
Publisher: Elsevier BV
Date: 02-2009
DOI: 10.1016/J.AJODO.2007.03.032
Abstract: The initial mechanical response to orthodontic loading comprises biologic reactions that remain unclear, despite their clinical significance. We used a 3-dimensional finite element analysis to investigate the stress-strain responses of teeth to orthodontic loading. The model was derived from computed tomography data, with adequate boundary conditions and tissue characterization, with orthodontic hardware to provide a more accurate reflection of events during orthodontic therapy. This study also incorporated the adjacent dentition. Two cases were analyzed: a single-tooth system with a mandibular canine, and a multi-tooth system consisting of the mandibular incisor, the canine, and the first premolar, subjected to orthodontic tipping forces. The systems experienced elevated distortion strain energies in the alveolar crest, whereas the tensile and compressive stresses coincided with the apical sites clinically associated with root resorption. Stress levels were considerably greater in the multi-tooth system than in the single-tooth system. The results for the single-tooth model agree with those previously reported. The numeric studies show how orthodontic tooth movement develops different stress fields and how root resorption might occur as a result of hydrostatic compressive stress-induced tissue necrosis.
A contact finite element algorithm for the multileaf spring of vehicle suspension systems
Publisher: SAGE Publications
Date: 03-2004
DOI: 10.1243/095440704322955821
Abstract: This paper presents an innovative finite element (FE) algorithm for the contact problem of the multileaf spring in vehicles. The well-established classic beam theory is adopted to construct the complementary strain energy variational. A piecewise contact stress pattern is approximated to the real contact state between two layered beams. The vector of nodal contact stresses is taken to represent primary state variables. To implement the principle of the least complementary energy, a quadratic programming (QP) problem with equality and unilateral constraints is formulated. The corresponding Kuhn-Tucker condition is equivalent to the linear complementary problem. In this study, Lemke's algorithm is applied to solve for the nodal stress vector and subsequently to determine the contact stress distribution over the contact surfaces between the layered beams. The algorithm is verified against experimental stress analysis, and it is found that the computation and test correlate well.
Multiscale metamaterials: a new route to isotropic double-negative behaviour at visible frequencies
Publisher: The Optical Society
Date: 03-09-2014
DOI: 10.1364/OE.22.021929
Crashworthiness design for foam filled thin-wall structures
Publisher: Elsevier BV
Date: 06-2009
Multiobjective optimization for crash safety design of vehicles using stepwise regression model
Publisher: Springer Science and Business Media LLC
Date: 20-11-2008
Computational fracture modelling in bioceramic structures
Publisher: Trans Tech Publications, Ltd.
Date: 07-2011
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMR.268-270.853
Abstract: Bioceramics have rapidly emerged as one of major biomaterials in modern biomedical applications because of its outstanding biocompatibility. However, one drawback is its low tensile strength and fracture toughness due to brittleness and inherent microstructural defects, which to a certain extent prevents the ceramics from fully replacing metals used as load-bearing prostheses. This paper aims to model the crack initiation and propagation in ceramic fixed partial denture, namely dental bridge, by using two recently developed methods namely continuum-to-discrete element method (CDEM) in ELFEN and extended finite element methods (XFEM) in ABAQUS. Unlike most existing studies that typically required prescriptions of initial cracks, these two new approaches will model crack initiation and propagation automatically. They are applied to a typical prosthodontic ex le, thereby demonstrating their applicability and effectiveness in biomedical applications.
Level-set based topology optimization for electromagnetic dipole antenna design
Publisher: Elsevier BV
Date: 09-2010
Stability analysis of generalized mass formulation in dynamic heat transfer
Publisher: Informa UK Limited
Date: 23-03-2016
Effects of buccal thickness augmentation on bone remodeling after maxillary anterior implantation
Publisher: Springer Science and Business Media LLC
Date: 08-08-2019
DOI: 10.1007/S10237-019-01200-X
Abstract: The biomechanics associated with buccal bone thickness (BBT) augmentation remains poorly understood, as there is no consistent agreement in the adequate BBT to avoid over-loading resorption or over-augmenting surgical difficulty. This study utilizes longitudinal clinical image data to establish a self-validating time-dependent finite element (FE)-based remodeling procedure to explore the effects of different buccal bone thicknesses on long-term bone remodeling outcomes in silico. Based upon the clinical computed tomography (CT) scans, a patient-specific heterogeneous FE model was constructed to enable virtual BBT augmentation at four different levels (0.5, 1.0, 1.5, and 2.0 mm), followed by investigation into the bone remodeling behavior of the different case scenarios. The findings indicated that although peri-implant bone resorption decreased with increasing initial BBT from 0.5 to 2 mm, different levels of the reduction in bone loss were associated with the amount of bone augmentation. In the case of 0.5 mm BBT, overloading resorption was triggered during the first 18 months, but such bone resorption was delayed when the BBT increased to 1.5 mm. It was found that when the BBT reached a threshold thickness of 1.5 mm, the bone volume can be better preserved. This finding agrees with the consensus in dental clinic, in which 1.5 mm BBT is considered clinically justifiable for surgical requirement of bone graft. In conclusion, this study introduced a self-validating bone remodeling algorithm in silico, and it ulged that the initial BBT affects the bone remodeling outcome significantly, and a sufficient initial BBT is considered essential to assure long-term stability and success of implant treatment.
Simultaneous Discrete Topology Optimization of Ply Orientation and Thickness for Carbon Fiber Reinforced Plastic-Laminated Structures
Publisher: ASME International
Date: 11-01-2019
DOI: 10.1115/1.4042222
Abstract: This study developed a discrete topology optimization procedure for the simultaneous design of ply orientation and thickness for carbon fiber reinforced plastic (CFRP)-laminated structures. A gradient-based discrete material and thickness optimization (DMTO) algorithm was developed by using casting-based explicit parameterization to suppress the intermediate void across the thickness of the laminate. A benchmark problem was first studied to compare the DMTO approach with the sequential three-phase design method using the free size, ply thickness, and stacking sequence of the laminates. Following this, the DMTO approach was applied to a practical design problem featuring a CFRP-laminated engine hood by minimizing overall compliance subject to volume-related and functional constraints under multiple load cases. To verify the optimized design, a prototype of the CFRP engine hood was created for experimental tests. The results showed that the simultaneous discrete topology optimization of ply orientation and thickness was an effective approach for the design of CFRP-laminated structures.
Nanomechanical characterization of time-dependent deformation/recovery on human dentin caused by radiation-induced glycation
Publisher: Elsevier BV
Date: 02-2019
DOI: 10.1016/J.JMBBM.2018.10.015
Abstract: An increase in non-enzymatic collagen matrix cross-links, such as advanced glycation end-products (AGEs), is known to be a major complication in human mineralized tissues, often causing abnormal fractures. However, degradation of mechanical properties in relation to AGEs has not been fully elucidated at the material level. Here, we report nanoscale time-dependent deformation and dimensional recovery of human tooth dentin that has undergone glycation induced by x-ray irradiation. The reduction in enzymatic collagen cross-linking and the increased level of AGEs with concomitant growth of disordered collagen matrix diminished creep deformation recovery in the lower mineralized target region. However, the elevated AGEs level alone did not cause a reduction in time-dependent deformation and its recovery in the higher mineralized target region. In addition to the elevated AGEs level, the degradation of the mechanical properties of mineralized tissues should be assessed with care in respect to multiple parameters in the collagen matrix at the molecular level.
Atomic layer deposition of Al2O3 and Al2O3/TiO2 barrier coatings to reduce the water vapour permeability of polyetheretherketone
Publisher: Elsevier BV
Date: 09-2015
On impact behavior of fiber metal laminate (FML) structures: A state-of-the-art review
Publisher: Elsevier BV
Date: 10-2021
Fishnet metamaterial with double negative refractive index in blue region of visible spectrum
Publisher: SPIE
Date: 11-09-2013
DOI: 10.1117/12.2035386
Comparative study on aluminum/GFRP/CFRP tubes for oblique lateral crushing
Publisher: Elsevier BV
Date: 07-2020
Design of graded two-phase microstructures for tailored elasticity gradients
Publisher: Springer Science and Business Media LLC
Date: 08-2008
Development and Validation of a High-Fidelity Finite-Element Model of Monopolar Stimulation in the Implanted Guinea Pig Cochlea
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2016
Crashworthiness analysis and optimization of sinusoidal corrugation tube
Publisher: Elsevier BV
Date: 08-2016
Biomechanics of oral mucosa
Publisher: The Royal Society
Date: 08-2015
Abstract: The prevalence of prosthodontic treatment has been well recognized, and the need is continuously increasing with the ageing population. While the oral mucosa plays a critical role in the treatment outcome, the associated biomechanics is not yet fully understood. Using the literature available, this paper provides a critical review on four aspects of mucosal biomechanics, including static, dynamic, volumetric and interactive responses, which are interpreted by its elasticity, viscosity ermeability, apparent Poisson's ratio and friction coefficient, respectively. Both empirical studies and numerical models are analysed and compared to gain anatomical and physiological insights. Furthermore, the clinical applications of such biomechanical knowledge on the mucosa are explored to address some critical concerns, including stimuli for tissue remodelling (interstitial hydrostatic pressure), pressure–pain thresholds, tissue displaceability and residual bone resorption. Through this review, the state of the art in mucosal biomechanics and their clinical implications are discussed for future research interests, including clinical applications, computational modelling, design optimization and prosthetic fabrication.
On lateral crashworthiness of aluminum/composite hybrid structures
Publisher: Elsevier BV
Date: 08-2020
Simulation of multi-stage nonlinear bone remodeling induced by fixed partial dentures of different configurations: a comparative clinical and numerical study
Publisher: Springer Science and Business Media LLC
Date: 15-09-2017
DOI: 10.1007/S10237-016-0826-X
Abstract: This paper aimed to develop a clinically validated bone remodeling algorithm by integrating bone's dynamic properties in a multi-stage fashion based on a four-year clinical follow-up of implant treatment. The configurational effects of fixed partial dentures (FPDs) were explored using a multi-stage remodeling rule. Three-dimensional real-time occlusal loads during maximum voluntary clenching were measured with a piezoelectric force transducer and were incorporated into a computerized tomography-based finite element mandibular model. Virtual X-ray images were generated based on simulation and statistically correlated with clinical data using linear regressions. The strain energy density-driven remodeling parameters were regulated over the time frame considered. A linear single-stage bone remodeling algorithm, with a single set of constant remodeling parameters, was found to poorly fit with clinical data through linear regression (low [Formula: see text] and R), whereas a time-dependent multi-stage algorithm better simulated the remodeling process (high [Formula: see text] and R) against the clinical results. The three-implant-supported and distally cantilevered FPDs presented noticeable and continuous bone apposition, mainly adjacent to the cervical and apical regions. The bridged and mesially cantilevered FPDs showed bone resorption or no visible bone formation in some areas. Time-dependent variation of bone remodeling parameters is recommended to better correlate remodeling simulation with clinical follow-up. The position of FPD pontics plays a critical role in mechanobiological functionality and bone remodeling. Caution should be exercised when selecting the cantilever FPD due to the risk of overloading bone resorption.
Roles of functional strain and capsule compression on mandibular cyst expansion and cortication
Publisher: Elsevier BV
Date: 02-2019
DOI: 10.1016/J.ARCHORALBIO.2018.10.035
Abstract: Cyst expansion in bone involves bone resorption but is often accompanied by adjacent bone formation with cortication. The mechanisms for these two apparently opposite processes remain unclear. From a mechanobiological perspective, functional strain drives bone remodeling, which involves both bone apposition and resorption. In this study, we explore the role of functional strain in cyst growth. Using a three-dimensional finite element analysis model of a simulated cyst at the of right first mandibular molar mesial apex, we examined three loading conditions, representing biting on the right molar, left molar and incisors, respectively. Comparison was made with an identical finite element model without the simulated cyst. Under all loading conditions, finite element analysis revealed higher strain energy density within the bone lining the cyst compared with the non-cyst model, which is consistent with bone formation and cortication observed clinically. Further analysis demonstrated overall compression of the simulated cyst capsule under all loading conditions.We interpret compression of the capsule as indicating resorption of the adjacent bone surface. We conclude that functional stress results in dominant compression of the soft tissue capsules of bony cysts, contributing to cyst expansion. Also, functional strain becomes elevated in the bone immediately adjacent to the soft tissue cyst capsule, which may drive bone formation and cortication.
Mandibular bone remodeling induced by dental implant
Publisher: Elsevier BV
Date: 2010
DOI: 10.1016/J.JBIOMECH.2009.08.024
Abstract: The ability to assess the effects of an implant on bone remodeling is of particular importance to prosthesis placement planning and associated treatment assurance. Prediction of on-going bone responses will enable us to improve the performance of a restoration. Although the bone remodeling for long bones had been extensively studied, there have been relatively few reports for dental scenarios despite its increasing significance with more and more dental implant placements. This paper aimed to develop a systematic protocol to assess mandibular bone remodeling induced by dental implantation, which extends the remodeling algorithms established for the long bones into dental settings. In this study, a 3D model for a segment of a human mandible was generated from in vivo CT scan images, together with a titanium implant embedded to the mandible. The results examined the changes in bone density and stiffness as a result of bone remodeling over a period of 48 months. Resonance frequency analysis was also performed to relate natural frequencies to bone remodeling. The density contours are qualitatively compared with clinical follow-up X-ray images, thereby providing validity for the bone remodeling algorithm presented in dental bone analysis.
Displacement minimization of thermoelastic structures by evolutionary thickness design
Publisher: Elsevier BV
Date: 09-1999
Experimental study on low-velocity impact responses and residual properties of composite sandwiches with metallic foam core
Publisher: Elsevier BV
Date: 09-2019
A reaction–diffusion based level set method for image segmentation in three dimensions
Publisher: Elsevier BV
Date: 11-2020
Experimental study on crashworthiness of empty/aluminum foam/honeycomb-filled CFRP tubes
Publisher: Elsevier BV
Date: 09-2016
Axial and lateral crushing responses of aluminum honeycombs filled with EPP foam
Publisher: Elsevier BV
Date: 12-2017
Design of 3-D periodic metamaterials for electromagnetic properties
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 04-2010
On hybrid cellular materials based on triply periodic minimal surfaces with extreme mechanical properties
Publisher: Elsevier BV
Date: 12-2019
Computational modeling of dynamic behaviors of human teeth
Publisher: Elsevier BV
Date: 12-2015
DOI: 10.1016/J.JBIOMECH.2015.10.019
Abstract: Despite the importance of dynamic behaviors of dental and periodontal structures to clinics, the biomechanical roles of anatomic sophistication and material properties in quantification of vibratory characteristics remain under-studied. This paper aimed to generate an anatomically accurate and structurally detailed 3D finite element (FE) maxilla model and explore the dynamic behaviors of human teeth through characterizing the natural frequencies (NFs) and mode shapes. The FE models with different levels of structural integrities and material properties were established to quantify the effects of modeling techniques on the computation of vibratory characteristics. The results showed that the integrity of computational model considerably influences the characterization of vibratory behaviors, as evidenced by declined NFs and perceptibly altered mode shapes resulting from the models with higher degrees of completeness and accuracy. A primary NF of 889Hz and the corresponding mode shape featuring linguo-buccal vibration of maxillary right 2nd molar were obtained based on the complete maxilla model. It was found that the periodontal ligament (PDL), a connective soft tissue, plays an important role in quantifying NFs. It was also revealed that d ing and heterogeneity of materials contribute to the quantification of vibratory characteristics. The study provided important biomechanical insights and clinical references for future studies on dynamic behaviors of dental and periodontal structures.
Experimental and numerical studies on multi-layered corrugated sandwich panels under crushing loading
Publisher: Elsevier BV
Date: 08-2015
Three-dimensional finite element modeling of Cochlear implant induced electrical current flows
Publisher: IEEE
Date: 05-2009
The mystery of coconut overturns the crashworthiness design of composite materials
Publisher: Elsevier BV
Date: 02-2020
The all-ceramic, inlay supported fixed partial denture. Part 2. Fixed partial denture design: a finite element analysis
Publisher: Wiley
Date: 10-07-2011
DOI: 10.1111/J.1834-7819.2011.01341.X
Abstract: The clinical use of all-ceramic crowns and fixed partial dentures has seen widespread adoption over the past few years due to their increasing durability and longevity. However, the application of inlays as an abutment design has not been as readily embraced because of their relatively high failure rates. With the use of an idealized inlay preparation design and prosthesis form which better distributes the tensile stresses, it is possible to utilize the inlay as support for an all-ceramic fixed partial denture. Utilizing a three-dimensional finite element analysis, a direct comparison of the inlay supported all-ceramic bridge against the traditional full crown supported all-ceramic bridge is made. The results demonstrate that peak stresses in the inlay bridge are around 20% higher than in the full crown supported bridge with von Mises peaking at about 730 MPa when subjected to theoretical average maximum bite force in the molar region of 700 N, which is similar to the ultimate tensile strengths of current zirconia based ceramics.
On design of multi-cell thin-wall structures for crashworthiness
Publisher: Elsevier BV
Date: 02-2016
Measurement of fracture parameters based upon digital image correlation and virtual crack closure techniques
Publisher: Elsevier BV
Date: 11-2021
Subject Specific Modelling of Electrical Conduction in the Body: A Case Study
Publisher: Trans Tech Publications, Ltd.
Date: 05-2011
DOI: 10.4028/WWW.SCIENTIFIC.NET/JBBTE.10.43
Abstract: Modelling of bioelectric phenomena in the human body poses unique problems compared to those encountered in other fields of engineering. Accurate definition of the physical domain and material properties is difficult due to geometrical complexity and uncertainty in tissue characterisation. A workflow is presented for finite element simulation of electric current in the body. This is illustrated through an application on a subject-specific cranial model for simulation of a cochlear implant. Operations required for the full workflow include: data acquisition, image registration and segmentation, material property assignment, numerical analysis, and visualisation. The case study described uses MRI imaging and diffusion tensor MRI for definition of the analysis domain and material properties with analysis conducted in ANSYS. Image registration and segmentation were accomplished using custom designed algorithms. Visualisation was achieved using a 24-bit red-green-blue colour scheme to represent directional vectors.
A novel failure criterion based upon forming limit curve for thermoplastic composites
Publisher: Elsevier BV
Date: 12-2020
On design of carbon fiber reinforced plastic (CFRP) laminated structure with different failure criteria
Publisher: Elsevier BV
Date: 04-2021
Numerical simulation of biomechanical behaviours in novel dental restorations
Publisher: Trans Tech Publications, Ltd.
Date: 05-2014
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMM.553.327
Abstract: Besides the prevention strategies against early stage dental caries, restoration is a preferable way to prevent decayed tooth from further deterioration. This study aimed to compare the mechanical strengths of carious tooth, traditionally restored tooth, and novel conservatively restored teeth under occlusal loading. The two-dimensional (2D) finite element method (FEM) was applied to quantify and compare maximum tensile stresses thereby predicting the initiation of crack. Taking into consideration of peak tensile stresses, it was found that the conservative (minimal intervention) restorations exhibited better fracture resistance than traditional restoration.
A machine learning-based multiscale model to predict bone formation in scaffolds
Publisher: Springer Science and Business Media LLC
Date: 20-08-2021
Validate mandible finite element model under removable partial denture (RPD) with in vivo pressure measurement
Publisher: Trans Tech Publications, Ltd.
Date: 05-2014
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMM.553.322
Abstract: This study aims to analyze the functional contact pressure induced by Removable Partial Denture (RPD) by using a 3D finite element (FE) model constructed based on patient specific CT scans. This model was validated against the in vivo test results. The outcomes demonstrate that the finite element simulation has the capability of quantifying localized stress distribution in a complicated denture-mucosa contact problem, with a reasonable matching to clinical measurements of occlusal force and pressure distribution. The methodology is of considerable clinical implication to improve the long term outcomes of the denture treatment.
Exceptional contact elasticity of human enamel in nanoindentation test
Publisher: Elsevier BV
Date: 2019
DOI: 10.1016/J.DENTAL.2018.11.005
Abstract: Tooth enamel has unsurpassed hardness and stiffness among mammalian tissue structures. Such stiff materials are usually brittle, yet mature enamel can survive for a lifetime. Understanding the nanoscale origin of enamel durability is important for developing advanced load-bearing biomaterials. Here, nanoscale exceptional contact elasticity of the human tooth enamel, based on nanoindentation tests, is reported. Spherical indenter tips with radii of 243 and 1041nm were used to determine stress-strain curves of enamel. Force-displacement curves were recorded using quasi-static loading strain rates of 0.031, 0.041, and 0.061s The elastic limits were 7-9GPa and 5-6GPa for the small and large indenters, respectively. The elastic-plastic transition point and elastic modulus value increased with substantially increased quasi-static loading strain rate. The results suggested that the increase of the elastic limit during high-loading strain was associated with exceptional contact elasticity at the nanoscale of the enamel structure and the consequent extension of the contact area (i.e., a temporary pile-up response, dependent on the enamel nanocrystals and protein glue). Structural modification at this scale effectively prevents the initiation of cracking from localized strain, thus reinforcing the bulk structure. These results may provide valuable insight for conceptualizing bio-inspired nanocomposites.
Sensitivity analysis for electromagnetic topology optimization problems
Publisher: IOP Publishing
Date: 06-2014
Bone metabolism induced by denture insertion in positron emission tomography
Publisher: Wiley
Date: 03-10-2016
DOI: 10.1111/JOOR.12356
Abstract: 18F-fluoride positron emission tomography (PET) can identify subtle functional variation prior to the major structural change detectable by X-ray. This study aims to investigate the mechanobiological bone reaction around the abutment tooth and in the residual ridge, induced by insertion of removable partial denture (RPD) within two different groups of patients: patients without denture experience (Group 1) and patients with denture experience before (Group 2), using 18F-fluoride PET imaging technique. 18F-fluoride PET/computerised tomography (CT) scan was performed to examine the bone metabolic change in mandible before and after the RPD treatment. Region of interests (ROIs) were placed in alveolar bone around abutment tooth and in residual bone beneath the RPD. Standardised uptake value (SUV), reflecting the accumulation of 18F-fluoride, was measured for each ROI. In all subjects of Group 1, SUVs after insertion were higher than before in both alveolar bone and residual bone, while there was less significant change in SUV in subjects of Group 2. This study demonstrated using longitudinal 18F-fluoride PET scans to effectively examine the bone metabolic change in mandible induced by occlusal loading after RPD insertion. Using this technique, within the six subjects in this study, it was shown that bone metabolism around abutment tooth and residual ridge increased after RPD insertion in case of first-time denture user, while there was no big change in the patient with experience of denture before. This study revealed the effectiveness of applying PET to evaluate bone metabolic activity as mechanobiological reaction.
Identification of Material Parameters for High Strength Steel Under Impact Loading
Publisher: American Scientific Publishers
Date: 03-2011
Determination of oral mucosal Poisson’s ratio and coefficient of friction from in-vivo contact pressure measurements
Publisher: Informa UK Limited
Date: 29-05-2016
DOI: 10.1080/10255842.2015.1028925
Abstract: Despite their considerable importance to biomechanics, there are no existing methods available to directly measure apparent Poisson's ratio and friction coefficient of oral mucosa. This study aimed to develop an inverse procedure to determine these two biomechanical parameters by utilizing in vivo experiment of contact pressure between partial denture and beneath mucosa through nonlinear finite element (FE) analysis and surrogate response surface (RS) modelling technique. First, the in vivo denture-mucosa contact pressure was measured by a tactile electronic sensing sheet. Second, a 3D FE model was constructed based on the patient CT images. Third, a range of apparent Poisson's ratios and the coefficients of friction from literature was considered as the design variables in a series of FE runs for constructing a RS surrogate model. Finally, the discrepancy between computed in silico and measured in vivo results was minimized to identify the best matching Poisson's ratio and coefficient of friction. The established non-invasive methodology was demonstrated effective to identify such biomechanical parameters of oral mucosa and can be potentially used for determining the biomaterial properties of other soft biological tissues.
Optimizaition for formability of plain woven carbon fiber fabrics
Publisher: Elsevier BV
Date: 05-2021
Histopathology image categorization with discriminative dimension reduction of fisher vectors
Publisher: Springer International Publishing
Date: 2016
Thermoelastic topology optimization for problems with varying temperature fields
Publisher: Informa UK Limited
Date: 04-2001
Synthetic Bone‐Like Structures Through Omnidirectional Ceramic Bioprinting in Cell Suspensions
Publisher: Wiley
Date: 20-01-2021
Experimental investigation of the quasi-static axial crushing behavior of filament-wound CFRP and aluminum/CFRP hybrid tubes
Publisher: Elsevier BV
Date: 06-2018
Experimental study on crashworthiness of tailor-welded blank (TWB) thin-walled high-strength steel (HSS) tubular structures
Publisher: Elsevier BV
Date: 2014
Evolutionary thickness design with stiffness maximization and stress minimization criteria
Publisher: Wiley
Date: 30-11-2001
DOI: 10.1002/NME.241
Design of bionic-bamboo thin-walled structures for energy absorption
Publisher: Elsevier BV
Date: 02-2019
Subject-specific finite element model with an optical tracking system in total hip replacement surgery
Publisher: SAGE Publications
Date: 04-2015
Abstract: Intra-operative peri-prosthetic femoral fractures are a significant concern in total hip arthroplasty and can occur at any time during surgery, with the highest incidence during implant insertion. This study combines subject-specific finite element analysis modeling with an optical tracking system to characterize the resultant strain in the bone and results of impaction during total hip replacement surgery. The use of ABG II femoral stem (Stryker Orthopaedics, Mahwah, NJ, USA) in the model yielded the following results. Hammer velocity was measured experimentally using a three-dimensional optical tracking system and these data were input into the finite element analysis model so that intra-operative loading scenario could be simulated. A quasi-static explicit simulation and a dynamic loading step using two implant–bone interface friction (0.1 and 0.4 friction coefficients) states were simulated. The maximum swing velocity of a mallet was experimentally measured at 1.5 m/s and occurred just before impaction of the hammer with implant introducer. Two friction states resulted in different results with the lower friction coefficient generating higher strains in the anterior regions of the model and higher displacement of the implant with respect to the femur when compared to the high friction state.
Fusing subcategory probabilities for texture classification
Publisher: IEEE
Date: 06-2015
Shell buckling: from morphogenesis of soft matter to prospective applications
Publisher: IOP Publishing
Date: 20-07-2018
Abstract: Being one of the commonest deformation modes for soft matter, shell buckling is the primary reason for the growth and nastic movement of many plants, as well as the formation of complex natural morphology. On-demand regulation of buckling-induced deformation associated with wrinkling, ruffling, folding, creasing and delaminating has profound implications for erse scopes, which can be seen in its broad applications in microfabrication, 4D printing, actuator and drug delivery. This paper reviews the recent remarkable developments in the shell buckling of soft matter to explain the most representative natural morphogenesis from the perspectives of theoretical analysis in continuum mechanics, finite element analysis, and experimental validations. Imitation of buckling-induced shape transformation and its applications are also discussed for the innovations of sophisticated materials and devices in future.
Effect of customized abutment taper configuration on bone remodeling and peri‐implant tissue around implant‐supported single crown: A 3D nonlinear finite element study
Publisher: Wiley
Date: 31-10-2023
DOI: 10.1111/JOPR.13776
Topology Optimization of Multicell Tubes Under Out-of-Plane Crushing Using a Modified Artificial Bee Colony Algorithm
Publisher: ASME International
Date: 18-05-2017
DOI: 10.1115/1.4036561
Abstract: Multicell tubal structures have generated increasing interest in engineering design for their excellent energy-absorbing characteristics when crushed through severe plastic deformation. To make more efficient use of the material, topology optimization was introduced to design multicell tubes under normal crushing. The design problem was formulated to maximize the energy absorption while constraining the structural mass. In this research, the presence or absence of inner walls were taken as design variables. To deal with such a highly nonlinear problem, a heuristic design methodology was proposed based on a modified artificial bee colony (ABC) algorithm, in which a constraint-driven mechanism was introduced to determine adjacent food sources for scout bees and neighborhood sources for employed and onlooker bees. The fitness function was customized according to the violation or the satisfaction of the constraints. This modified ABC algorithm was first verified by a square tube with seven design variables and then applied to four other ex les with more design variables. The results demonstrated that the proposed heuristic algorithm is capable of handling the topology optimization of multicell tubes under out-of-plane crushing. They also confirmed that the optimized topological designs tend to allocate the material at the corners and around the outer walls. Moreover, the modified ABC algorithm was found to perform better than a genetic algorithm (GA) and traditional ABC in terms of best, worst, and average designs and the probability of obtaining the true optimal topological configuration.
Finite Element Modeling of Current Flow from Cochlear Implant Stimulation
Publisher: ACTAPRESS
Date: 2011
Crashworthiness design of multi-component tailor-welded blank (TWB) structures
Publisher: Springer Science and Business Media LLC
Date: 03-04-2013
Influence of tooth removal on mandibular bone response to mastication
Publisher: Elsevier BV
Date: 12-2008
DOI: 10.1016/J.ARCHORALBIO.2008.06.013
Abstract: The quantification of biomechanical response of mandibular bone to mastication is an integral component for a key in understanding the biological consequence of masticatory functions. Understanding the response of mandibular bone to external loading may also well explain the mechanisms of bone turnover. In this study, three finite element (FE) models simulating the lower second premolar, first and second molars along with their supporting structures were developed to determine stress/strain levels and distribution under different occlusal loading. The changes in stress/strain values and profiles have been investigated in three scenarios: pre-extraction of the lower first molar, post-extraction and after full healing of the extracted socket. The mastication induced equivalent strains within the supporting mandibular bone at each of these three scenarios were quantified and compared against the Frost's mechanostat theory. The results of stress/strain profiles show considerably lower magnitudes in the post-extracted and healed scenarios compared with the pre-extraction case. Following the Frost's MES hypothesis, the initial equivalent strains are related to local bone remodelling. It is found that in the extracted case the bone near the tooth socket undergoes resorption from lingual respect whilst filling the cavity, whereas in the healed case bone turnover reaches equilibrium. The results provide important data for clinical assessment of constructing dentures or other restorative devices.
Three-dimensional reconstruction of internal fascicles and microvascular structures of human peripheral nerves
Publisher: Wiley
Date: 29-08-2019
DOI: 10.1002/CNM.3245
Abstract: Biofabricated nanostructured and microstructured scaffolds have exhibited great potential for nerve tissue regeneration and functional restoration, and prevascularization and biotransportation within 3D fascicle structures are critical. Unfortunately, an ideal internal fascicle and microvascular model of human peripheral nerves is lacking. In this study, we used microcomputed tomography (microCT) to acquire high-resolution images of the human sciatic nerve. We propose a novel deep-learning network technique, called ResNetH3D-Unet, to segment fascicles and microvascular structures. We reconstructed 3D intraneural fascicles and microvascular topography to quantify the fascicle volume ratio (FVR), microvascular volume ratio (MVR), microvascular to fascicle volume ratio (MFVR), fascicle surface area to volume ratio (FSAVR), and microvascular surface area to volume ratio (MSAVR) of human s les. The frequency distributions of the fascicle diameter, microvascular diameter, and fascicle-to-microvasculature distance were analyzed. The obtained microCT analysis and reconstruction provided high-resolution microstructures of human peripheral nerves. Our proposed ResNetH3D-Unet method for fascicle and microvasculature segmentation yielded a mean intersection over union (IOU) of 92.1% (approximately 5% higher than the U-net IOU). The 3D reconstructed model showed that the internal microvasculature runs longitudinally within the internal epineurium and connects to the external vasculature at some points. Analysis of the 3D data indicated a 48.2 ± 3% FVR, 23.7 ± 1.8% MVR, 4.9 ± 0.5% MFVR, 7.26 ± 2.58 mm
Quasi-static bending and transverse crushing behaviors for hat-shaped composite tubes made of CFRP, GFRP and their hybrid structures
Publisher: Elsevier BV
Date: 05-2020
Yielding behaviors of polymeric scaffolds with implications to tissue engineering
Publisher: Elsevier BV
Date: 12-2016
Improved impact property of long glass fiber‐reinforced polypropylene random copolymer composites toughened with beta‐nucleating agent via tunning the crystallization and phase
Publisher: Wiley
Date: 29-03-2021
DOI: 10.1002/PC.26047
Abstract: Crystallization and phase engineering offer a promising route to significantly improve the impact property of long glass fiber‐reinforced polypropylene random copolymer (LGF/PPR) composites. However, the nucleation and crystallization mechanism in the crystallization process, and the resulting phase change mechanism are still unclear, which severely limits the remarkable improvement of the toughness of LGF/PPR composites. Herein, we successfully fabricate toughened LGF/PPR composites with excellent heat deflection temperature and impact toughness via tuning the crystallization behavior and phase structure generated by introducing β ‐nucleating agent ( β ‐NA). Through differential scanning calorimeter and wide‐angle X‐ray diffraction analysis, the influence of LGF and β ‐NA on the nucleation and crystallization mechanism of the PPR matrix was revealed. Therefore, the critical crystallization parameters were calculated, and then the correlation was established with tensile and impact properties through regression analysis. The results show that the impact strength of β ‐PPR and β ‐LGF/PPR/MPPR are remarkably increased by 50.1% and 26.3% at the critical β ‐NA content of 0.2 and 0.1 wt%, respectively, due to the intrinsic toughening mechanism. This work may pave the way for preparing a class of LGF/PPR composites with high‐impact toughness.
Topological design of structures and composite materials with multiobjectives
Publisher: Elsevier BV
Date: 11-2007
Fatigue reliability analysis for vibroseis baseplates
Publisher: Wiley
Date: 27-04-2016
DOI: 10.1111/FFE.12467
Quasi-static and low-velocity impact responses of polypropylene random copolymer composites with adjustable crystalline structures
Publisher: Elsevier BV
Date: 11-2021
The effect of seated pelvic tilt on posterior edge-loading in total hip arthroplasty: A finite element investigation
Publisher: SAGE Publications
Date: 10-01-2018
Abstract: Edge-loading of a ceramic-on-ceramic total hip replacement can lead to reproducible squeaking and revision. A patient’s functional acetabular cup orientation, driven by their pelvic tilt, has been shown to be a significant factor in squeaking during hip flexion. The aim of this study was to investigate the effect of seated pelvic tilt on the contact mechanics at the ceramic bearing surface. A finite element model of a ceramic-on-ceramic total hip replacement was created. The cup was orientated at 40° inclination and 15° anteversion relative to the anterior pelvic plane. The stem was flexed 90° to replicate sitting in a chair. The model was loaded using data from in vivo measurements taken during a sit-to-stand activity. The pelvis was modelled in seven different sagittal positions, ranging from −30° to 30° of pelvic tilt, where a positive value denotes anterior pelvic tilt. Three different head sizes were investigated: 32, 36 and 40 mm. The maximum contact pressure and contact patch to rim distance were determined for each of the 21 simulations. Edge-loading (contact patch to rim distance 0 mm) occurred with all head sizes when seated pelvic tilt was ≥10° and induced a large increase in contact pressure on the liner, with a maximum pressure exceeding 500 MPa. Edge-loading initiated at seated pelvic tilts of 7°, 9° and 5° for the 32, 36 and 40 mm heads, respectively. Patients with anterior pelvic tilts in the seated position are susceptible to posterior edge-loading. As the position of the pelvis when seated is patient specific, cup orientation should be adjusted on an in idual basis to minimise edge-loading.
The relation of constant mean curvature surfaces to multiphase composites with extremal thermal conductivity
Publisher: IOP Publishing
Date: 21-09-2007
Bone morphological effects on post-implantation remodeling of maxillary anterior buccal bone: A clinical and biomechanical study
Publisher: Japan Prosthodontic Society
Date: 10-2017
DOI: 10.1016/J.JPOR.2016.12.010
Abstract: This study combines clinical investigation with finite element (FE) analysis to explore the effects of buccal bone thickness (BBT) on the morphological changes of buccal bone induced by the loaded implant. One specific patient who had undergone an implant treatment in the anterior maxilla and experienced the buccal bone resorption on the implant was studied. Morphological changes of the bone were measured through a series of cone-beam computed tomography (CT) scans. A three-dimensional heterogeneous nonlinear FE model was constructed based on the CT images of this patient, and the in-vivo BBT changes are correlated to the FE in-silico mechanobiological stimuli namely, von Mises equivalent stress, equivalent strain, and strain energy density. The anterior incisory bone region of this model was then varied systematically to simulate five different BBTs (0.5, 1.0, 1.5, 2.0, and 2.5mm), and the optimal BBT was inversely determined to minimize the risk of resorption. Significant changes in BBTs were observed clinically after 6 month loading on the implant. The pattern of bone resorption fell into a strong correlation with the distribution of mechanobiological stimuli onsite. The initial BBT appeared to play a critical role in distributing mechanobiological stimuli, thereby determining subsequent variation in BBT. A minimum initial thickness of 1.5mm might be suggested to reduce bone resorption. This study revealed that the initial BBT can significantly affect mechanobiological responses, which consequentially determines the bone remodeling process. A sufficient initial BBT is considered essential to assure a long-term stability of implant treatment.
Monolithic crowns fracture analysis: The effect of material properties, cusp angle and crown thickness
Publisher: Elsevier BV
Date: 08-2020
Magnetic Resonance Imaging (MRI) Based Finite Element Modeling for Analyzing the Influence of Material Properties on Menisci Responses
Publisher: Trans Tech Publications, Ltd.
Date: 05-2014
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMM.553.305
Abstract: To investigate the importance of the meniscal non-linear behaviour on knee joint finite element analysis (FEA) study, the aim of this study was to compare linear elastic and nonlinear hyperelastic material models on the pressure distribution of meniscus. For this purpose, a 3D finite element (FE) knee model of a healthy living subject was constructed from magnetic resonance imaging (MRI) to simulate contact pressure under axial compressive loading. Differences in meniscal contact pressures were observed between linear elastic and nonlinear hyperelastic models. These findings emphasize the importance of accounting the nonlinear material behaviour of the menisci in knee joint FEA studies.
A hybrid adaptive Kriging-based single loop approach for complex reliability-based design optimization problems
Publisher: Elsevier BV
Date: 11-2021
In vivo effects of different orthodontic loading on root resorption and correlation with mechanobiological stimulus in periodontal ligament
Publisher: The Royal Society
Date: 05-2019
Abstract: Orthodontic root resorption is a common side effect of orthodontic therapy. It has been shown that high hydrostatic pressure in the periodontal ligament (PDL) generated by orthodontic forces will trigger recruitment of odontoclasts, leaving resorption craters on root surfaces. The patterns of resorption craters are the traces of odontoclast activity. This study aimed to investigate resorptive patterns by: (i) quantifying spatial root resorption under two different levels of in vivo orthodontic loadings using microCT imaging techniques and (ii) correlating the spatial distribution pattern of resorption craters with the induced mechanobiological stimulus field in PDL through nonlinear finite-element analysis (FEA) in silico . Results indicated that the heavy force led to a larger total resorption volume than the light force, mainly by presenting greater in idual crater volumes ( p 0.001) than increasing crater numbers, suggesting that increased mechano-stimulus predominantly boosted cellular resorption activity rather than recruiting more odontoclasts. Furthermore, buccal–cervical and lingual–apical regions in both groups were found to have significantly larger resorption volumes than other regions ( p 0.005). These clinical observations are complemented by the FEA results, suggesting that root resorption was more likely to occur when the volume average compressive hydrostatic pressure exceeded the capillary blood pressure (4.7 kPa).
A comparison of fast Fourier transform-based homogenization method to asymptotic homogenization method
Publisher: Elsevier BV
Date: 04-2020
The Effect of a Degenerative Spine and Adverse Pelvic Mobility on Prosthetic Impingement in Patients Undergoing Total Hip Arthroplasty
Publisher: Elsevier BV
Date: 07-2021
On the Topology Optimization of Elastic Supporting Structures under Thermomechanical Loads
Publisher: Hindawi Limited
Date: 2016
DOI: 10.1155/2016/7372603
Abstract: This paper is to present a thermomechanical topology optimization formulation. By designing structures that support specific nondesignable domain, optimization is to suppress the stress level in the nondesignable domain and maintain global stiffness simultaneously. A global stress measure based on p -norm function is then utilized to reduce the number of stress constraints in topology optimization. Sensitivity analysis employs adjoint method to derive the global stress measure with respect to the topological pseudodensity variables. Some particular behaviors in thermomechanical topology optimization of elastic supports, such as the influence of different thermomechanical loads and the existence of intermediate material, are also analyzed numerically. Finally, ex les of elastic supports on a cantilever beam and a nozzle flap under different thermomechanical loads are tested with reasonable optimized design obtained.
Improving antistatic and mechanical properties of glass fiber reinforced polypropylene composites through polar adsorption and anchoring effect of organic salt
Publisher: Elsevier BV
Date: 03-2022
On lower confidence bound improvement matrix-based approaches for multiobjective Bayesian optimization and its applications to thin-walled structures
Publisher: Elsevier BV
Date: 04-2021
Sensitivity analysis and reliability based design optimization for high-strength steel tailor welded thin-walled structures under crashworthiness
Publisher: Elsevier BV
Date: 12-2016
Level-set topology optimization for maximizing fracture resistance of brittle materials using phase-field fracture model
Publisher: Wiley
Date: 09-03-2020
DOI: 10.1002/NME.6340
Multiobjective sequential optimization for a vehicle door using hybrid materials tailor-welded structure
Publisher: SAGE Publications
Date: 09-08-2016
Abstract: To achieve lightweight vehicle door, this paper presents a novel design with a hybrid material tailor-welded structure (HMTWS). A multiobjective optimization procedure is adopted to generate a set of solutions, in which the door stiffness and mass are taken as objective functions, and the material types and plate thicknesses are regarded as the discrete and continuous design variables, respectively. To improve the optimization efficiency, Kriging algorithm is used for generating surrogate model through a sequential s ling strategy. The non-dominated sorting genetic algorithm II (NSGA-II) is employed to perform the multiobjective optimization. It is found that for the same computational cost, the sequential s ling strategy can yield more accurate optimization results than the conventional one-step s ling strategy. Most importantly, HMTWS is found more competent than the traditional thin-walled configurations made of steel or other lighter mono-materials for maximizing the usage of materials and stiffness of the vehicular door structures.
Identification of mechanical properties of the weld line by combining 3D digital image correlation with inverse modeling procedure
Publisher: Springer Science and Business Media LLC
Date: 14-06-2014
Biomechanical response in mandibular bone due to mastication loading on 3-unit fixed partial dentures
Publisher: Portico
Date: 2010
DOI: 10.4061/2010/902537
Evolutionary structural optimization for stress minimization problems by discrete thickness design
Publisher: Elsevier BV
Date: 12-2000
Optimizing two-level hierarchical particles for thin-film solar cells
Publisher: The Optical Society
Date: 26-02-2013
DOI: 10.1364/OE.21.00A285
Surface morphology optimization for osseointegration of coated implants
Publisher: Elsevier BV
Date: 09-2010
DOI: 10.1016/J.BIOMATERIALS.2010.05.077
Abstract: This paper aims to establish a relationship between the surface morphology induced micromechanics and bone remodeling responses to a solid bead coated porous implant and further to develop a multiobjective optimization framework for the coating design of biomaterials. Multiscale modeling and remodeling techniques were developed, where a macroscopic analysis was initially performed to generate a global response to enable a microscopic analysis. The bone remodeling responses of the microscopic models (with a specific surface morphology) were evaluated in terms of the average apparent density developed in the peri-implant region. To explore the proposed multiscale analysis and design methods, a typical dental implantation setting is exemplified in this study. The response surface method (RSM) was utilized to relate the major implant coating parameters to the bone responses. It is found that increasing the volume fraction of the coating beads articles results in a greater bone density, whereas increasing bead article size does not significantly affect the bone's responses. Several different multiobjective optimization schemes were adopted to optimize the coated bead size and volume fraction, which reveal that the optimal design parameters of particle diameter and volume fraction are 100 microm--35% and 38 microm--17.5% for the cortical and cancellous bones respectively, agreeing with clinical data. To maximize the implant/bone interfacial stability, specific surface coating designs for particular locations are recommended.
Fracture modeling of brittle biomaterials by the phase-field method
Publisher: Elsevier BV
Date: 12-2202
The design of functional gradient materials with inverse homogenization method
Publisher: Trans Tech Publications Ltd.
Date: 09-02-2008
Crashworthiness optimization of foam-filled tapered thin-walled structure using multiple surrogate models
Publisher: Springer Science and Business Media LLC
Date: 19-07-2012
How does negative Poisson's ratio of foam filler affect crashworthiness?
Publisher: Elsevier BV
Date: 10-2015
Nondestructive characterization of bone tissue scaffolds for clinical scenarios
Publisher: Elsevier BV
Date: 2018
DOI: 10.1016/J.JMBBM.2018.08.034
Abstract: This study aimed to develop a simple and efficient numerical modeling approach for characterizing strain and total strain energy in bone scaffolds implanted in patient-specific anatomical sites. A simplified homogenization technique was developed to substitute a detailed scaffold model with the same size and equivalent orthotropic material properties. The effectiveness of the proposed modeling approach was compared with two other common homogenization methods based on periodic boundary conditions and the Hills-energy theorem. Moreover, experimental digital image correlation (DIC) measurements of full-field surface strain were conducted to validate the numerical results. The newly proposed simplified homogenization approach allowed for fairly accurate prediction of strain and total strain energy in tissue scaffolds implanted in a large femur mid-shaft bone defect subjected to a simulated in-vivo loading condition. The maximum discrepancy between the total strain energy obtained from the simplified homogenization approach and the one obtained from detailed porous scaffolds was 8.8%. Moreover, the proposed modeling technique could significantly reduce the computational cost (by about 300 times) required for simulating an in-vivo bone scaffolding scenario as the required degrees of freedom (DoF) was reduced from about 26 million for a detailed porous scaffold to only 90,000 for the homogenized solid counterpart in the analysis. The simplified homogenization approach has been validated by correlation with the experimental DIC measurements. It is fairly efficient and comparable with some other common homogenization techniques in terms of accuracy. The proposed method is implicating to different clinical applications, such as the optimal selection of patient-specific fixation plates and screw system.
Fatigue behavior of carbon fibre reinforced plastic and aluminum single-lap adhesive joints after the transverse pre-impact
Publisher: Elsevier BV
Date: 03-2021
On quasi-static behaviors of different joint methods for connecting carbon fiber reinforce plastic (CFRP) laminate and aluminum alloy
Publisher: Elsevier BV
Date: 07-2021
Design optimization of regular hexagonal thin-walled columns with crashworthiness criteria
Publisher: Elsevier BV
Date: 04-2007
Phase field fracture in elasto-plastic solids: Abaqus implementation and case studies
Publisher: Elsevier BV
Date: 10-2019
On design of graded honeycomb filler and tubal wall thickness for multiple load cases
Publisher: Elsevier BV
Date: 12-2016
Configurational optimization of multi-cell topologies for multiple oblique loads
Publisher: Springer Science and Business Media LLC
Date: 08-11-2017
Nondeterministic multi-objective and multi-case discrete optimization of functionally-graded front-bumper structures for pedestrian protection
Publisher: Elsevier BV
Date: 10-2021
Bone remodeling induced by dental implants of functionally graded materials
Publisher: Wiley
Date: 19-11-2009
DOI: 10.1002/JBM.B.31531
Abstract: Functionally graded material (FGM) had been developed as a potential implant material to replace titanium for its improved capability of initial osseointegration. The idea behind FGM dental implant is that its properties can be tailored in accordance with the biomechanical needs at different regions adapting to its hosting bony tissues, therefore creating an improved overall integration and stability in the entire restoration. However, there have been very few reports available so far on predicting bone remodeling induced by FGM dental implants. This article aims to evaluate bone remodeling when replacing the titanium with a hydroxyapatite/collagen (HAP/Col) FGM model. A finite element model was constructed in the buccal-lingual section of a dental implant-bone structure generated from in vivo CT scan images. The remodeling simulation was performed over a 4 year healing period. Comparisons were made between the titanium implant and various FGM implants of this model. The FGM implants showed an improved bone remodeling outcome. The study is expected to provide a basis for future development of FGM implants.
A Comparative study on multiobjective reliable and robust optimization for crashworthiness design of vehicle structure
Publisher: Springer Science and Business Media LLC
Date: 09-04-2013
Computational design of multi-phase microstructural materials for extremal conductivity
Publisher: Elsevier BV
Date: 09-2008
Interfacial Curvature in Confined Coculture Directs Stromal Cell Activity with Spatial Corralling of Pancreatic Cancer Cells
Publisher: Wiley
Date: 22-03-2021
Abstract: Interfacial cues in the tumor microenvironment direct the activity and assembly of multiple cell types. Pancreatic cancer, along with breast and prostate cancers, is enriched with cancer‐associated fibroblasts (CAFs) that activate to coordinate the deposition of the extracellular matrix, which can comprise over 90% of the tumor mass. While it is clear that matrix underlies the severity of the disease, the relationship between stromal‐tumor cell assembly and cell‐matrix dynamics remains elusive. Micropatterned hydrogels deconstruct the interplay between matrix stiffness and geometric confinement, guiding heterotypic cell populations and matrix assembly in pancreatic cancer. Interfacial cues at the perimeter of microislands guide CAF migration and direct cancer cell assembly. Computational modeling shows curvature‐stress dependent cellular localization for cancer and CAFs in coculture. Regions of convex curvature enhance edge stress that activates a myofibroblast phenotype in the CAFs with migration and increased collagen I deposition, ultimately leading to a central “corralling” of cancer cells. Inhibiting mechanotransduction pathways decreases CAF activation and the associated corralling phenotype. Together, this work reveals how interfacial biophysical cues underpin aspects of stromal desmoplasia, a hallmark of disease severity and chemoresistance in the pancreatic, breast, and prostate cancers, thereby providing a tool to expand stroma‐targeting therapeutic strategies.
The all-ceramic, inlay supported fixed partial denture. Part 3. Experimental approach for validating the finite element analysis
Publisher: Wiley
Date: 28-02-2012
DOI: 10.1111/J.1834-7819.2011.01638.X
Abstract: In a previous study, the authors used a finite element analysis (FEA) to evaluate the stresses developed during the loading of an all-ceramic, inlay supported fixed partial denture and compared it with the more traditional full crown supported prosthesis. To date there has been little research into correlating the responses of the numerical model against physical mechanical tests such validation analysis is crucial if the results from the FEA are to be confidently relied upon. This study reports on the experimental methods used to compare with the FEA and thereby to validate the predictive fracture behaviour of the numerical model. This study also outlines the methods for manufacture and testing of the ceramic structure along with observations of the fracture tests. In addition the procedure used for developing the FEA model for the test system is outlined.
Design optimization of bioinspired helicoidal CFRPP/GFRPP hybrid composites for multiple low-velocity impact loads
Publisher: Elsevier BV
Date: 04-2022
Energy absorption of metal, composite and metal/composite hybrid structures under oblique crushing loading
Publisher: Elsevier BV
Date: 2018
Quasi-static axial crushing and transverse bending of double hat shaped CFRP tubes
Publisher: Elsevier BV
Date: 11-2014
Computational design of microstructural composites with tailored thermal conductivity
Publisher: Informa UK Limited
Date: 12-09-2008
Assessing the effects of natural variations in microstructure for the biomimetic modeling of cuttlebone
Publisher: Trans Tech Publications, Ltd.
Date: 08-2010
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMR.123-125.295
Abstract: Cuttlebone is a natural material possessing a unique microstructure providing a high compressive strength to weight ratio. It is potentially desirable to use cuttlebone directly in engineering applications or to design new biomimetic materials based on the microstructural features of cuttlebone. A finite element based homogenization method can be used for characterizing the mechanical properties of such a biomaterial and for the design of biomimetic materials. However, this method assumes a periodicity of microstructure, which does not reflect the variation present in natural or fabricated materials. The method can be extended to investigate the effect of natural variation and manufacturing tolerance by enlarging the base cell domain to include a number of representative volume elements (RVEs) and applying a random displacement vector to the nodes at the internal intersections of the RVEs. As the boundary of the base cell domain is not modified, the homogenization method can still be employed to calculate the bulk mechanical properties. It is found that the number of RVEs in the base cell has an impact on the decrease in mean stiffness tensor components, while the length of the introduced variation seems to influence both the mean and the standard deviation of stiffness tensor components.
An experimental study on fatigue characteristics of CFRP-steel hybrid laminates
Publisher: Elsevier BV
Date: 12-2015
Multiobjective crashworthiness optimization of hollow and conical tubes for multiple load cases
Publisher: Elsevier BV
Date: 09-2014
Mechanical failure of posterior teeth due to caries and occlusal wear- A modelling study
Publisher: Elsevier BV
Date: 2022
Numerical homogenization for incompressible materials using selective smoothed finite element method
Publisher: Elsevier BV
Date: 05-2015
Crushing responses and energy absorption behaviors of multi-cell CFRP tubes
Publisher: Elsevier BV
Date: 10-2020
Bioinspired lightweight cellular materials - Understanding effects of natural variation on mechanical properties
Publisher: Elsevier BV
Date: 08-2013
DOI: 10.1016/J.MSEC.2013.03.031
Abstract: Cuttlebone is a natural marine cellular material possessing the exceptional mechanical properties of high compressive strength, high porosity and high permeability. This combination of properties is exceedingly desirable in biomedical applications, such as bone tissue scaffolds. In light of recent studies, which converted raw cuttlebone into hydroxyapatite tissue scaffolds, the impact of morphological variations in the microstructure of this natural cellular material on the effective mechanical properties is explored in this paper. Two extensions of the finite element-based homogenization method are employed to account for deviations from the assumption of periodicity. Firstly, a representative volume element (RVE) of cuttlebone is systematically varied to reflect the large range of microstructural configurations possibly among different cuttlefish species. The homogenization results reveal the critical importance of pillar formation and aspect ratio (height/width of RVE) on the effective bulk and shear moduli of cuttlebone. Secondly, multi-cell analysis domains (or multiple RVE domains) permit the introduction of random variations across neighboring cells. Such random variations decrease the bulk modulus whilst displaying minimal impact on the shear modulus. Increasing the average size of random variations increases the effect on bulk modulus. Also, the results converge rapidly as the size of the analysis domain is increased, meaning that a relatively small multi-cell domain can provide a reasonable approximation of the effective properties for a given set of random variation parameters. These results have important implications for the proposed use of raw cuttlebone as an engineering material. They also highlight some potential for biomimetic design capabilities for materials inspired by the cuttlebone microstructure, which may be applicable in biomedical applications such as bone tissue scaffolds.
On reliability analysis method through rotational sparse grid nodes
Publisher: Elsevier BV
Date: 2021
A simple checkerboard suppression algorithm for evolutionary structural optimization
Publisher: Springer Science and Business Media LLC
Date: 10-2001
Multiobjective optimization on cooperative control of autonomous emergency steering and occupant restraint system for enhancing occupant safety
Publisher: Elsevier BV
Date: 09-2021
Inverse identification of cell-wall material properties of closed-cell aluminum foams based upon Vickers nano-indentation tests
Publisher: Elsevier BV
Date: 06-2020
On the effects of temperature on tensile behavior of carbon fiber reinforced epoxy laminates
Publisher: Elsevier BV
Date: 07-2021
Mathematical modeling of polymer biodegradation and erosion
Publisher: Trans Tech Publications, Ltd.
Date: 06-2010
DOI: 10.4028/WWW.SCIENTIFIC.NET/MSF.654-656.2071
Abstract: The biodegradable polymers are widely used in therapeutic surgery and pharmaceutics, in which the degradation process has drawn significant attention in recent years. In this paper, we propose a mathematical model to predict the polymer degradation in tissue engineering applications. A stochastic model is introduced to characterize the hydrolysis reaction in an elemental basis and the mass transport is also performed to investigate the diffusive transport of polymer erosion. Two representative polymeric films in different configurations are studied. It is found that for biodegradable systems, mass transport plays an important role in controlling the erosion pathway, in which the matrix configuration could be one of the key factors that determine the characteristics of erosion and drug release rates. The proposed model makes a useful benefit to the design optimization of the matrix architectures for biodegradable devices.
Tonal optimization of bells utilizing evolutionary shape optimization
Publisher: Elsevier BV
Date: 09-2021
Dynamic crash responses of bio-inspired aluminum honeycomb sandwich structures with CFRP panels
Publisher: Elsevier BV
Date: 07-2017
A modular design strategy to integrate mechanotransduction concepts in scaffold-based bone tissue engineering
Publisher: Elsevier BV
Date: 12-2020
Phase field fracture in elasto-plastic solids: a length-scale insensitive model for quasi-brittle materials
Publisher: Springer Science and Business Media LLC
Date: 10-08-2020
A finite-element approach to evaluating the size effects of complex nanostructures
Publisher: The Royal Society
Date: 12-2016
DOI: 10.1098/RSOS.160625
Abstract: The size effects that reveal the dramatic changes of mechanical behaviour at nanoscales have traditionally been analysed for regular beam systems. Here, the method of using finite-element analysis is explored with the intention of evaluating the size effects for complex nanostructures. The surface elasticity theory and generalized Young–Laplace equation are integrated into a beam element to account for the size effects in classical Euler–Bernoulli and Timoshenko beam theories. Computational results match well with the theoretical predictions on the size effect for a cantilever beam and a cubic unit cell containing 24 horizontal/vertical ligaments. For a simply supported nanowire, it is found that the results are very close to the experimental data. With the assumption that nanoporous gold is composed of many randomly connected beams, for the first time, the size effect of such a complex structure is numerically determined.
Mechanical properties of hybrid composites reinforced by carbon and basalt fibers
Publisher: Elsevier BV
Date: 11-2018
Multiscale design of surface morphological gradient for osseointegration
Publisher: Elsevier BV
Date: 04-2013
DOI: 10.1016/J.JMBBM.2012.08.019
Abstract: Rapid and stable osseointegration signifies a major concern in design of implantable prostheses, which stimulates continuous development of new implant materials and structures. This study aims to develop a graded configuration of a bead article coated porous surface for implants by exploring how its micromechanical features determine osseointegration through multiscale modeling and remodeling techniques. A typical dental implantation setting was exemplified for investigation by using the remodeling parameters determined from a systematic review of bone-implant-contact (BIC) ratio published in literature. The global responses of a macroscale model were obtained through 48 month remodeling simulation, which forms the basis for the 27 microscopic models created with different particle gradients ranging from 30 to 70μm. The osseointegration responses are evaluated in terms of the BIC ratio and the averaged 10% peak Tresca shear stress (PTS). Within the s ling designs considered, the configuration with 50-30-30μm particle sizes provides the best outcome, counting 20% more BIC ratio and 0.17MPa less PTS compared with the worst case scenario, also outperforming the best uniform morphology of 70μm particles. Furthermore, the response surface method (RSM) was utilized to formulate the bone remodeling responses in terms of gradient parameters across three layers. Gradient 30.0-30.0-32.1 is found an optimal gradient for BIC ratio, and 70-45.4-40.8 the best for the minimum PTS. The multiobjective optimization was finally performed to simultaneously maximize BIC ratio and minimize PTS for achieving the best possible overall outcome. Due to strong competition between these two design objectives, a Pareto front is generated. To make a proper trade-off, the minimum distance selection criterion is considered and the gradient of 37.1-70.0-67.7 appears an optimal solution. This study provides a novel surface configuration and design methodology for in idual patient that allow optimizing topographical gradient for a desirable patient-specific biomechanical environment to promote osseointegration.
Robust topology optimization for multiple fiber-reinforced plastic (FRP) composites under loading uncertainties
Publisher: Springer Science and Business Media LLC
Date: 07-01-2019
On equivalence between stress criterion and stiffness criterion in evolutionary structural optimization
Publisher: Springer Science and Business Media LLC
Date: 08-1999
DOI: 10.1007/BF01210693
Restoration of non-carious cervical lesions. Part II. Restorative material selection to minimise fracture
Publisher: Elsevier BV
Date: 12-2007
DOI: 10.1016/J.DENTAL.2007.02.002
Abstract: It is still largely unknown as to what material parameter requirements would be most suitable to minimise the fracture and maximising the retention rate of the restoration of cervical non-carious lesions (NCCL). The present paper, as a first of its kind, proposes a radical approach to address the problems of material improvement, namely: numerical-based, fracture and damage mechanics materials optimisation engineering. It investigates the influence of the elastic modulus (E) on the failure of cervical restorative materials and aims to identify an E value that will minimise mechanical failure under clinically realistic loading conditions. The present work relies on the principle that a more flexible restorative material would partially buffer the local stress concentration. We employ a "most favourable" parametric analysis of the restorative's elastic modulus using a fracture mechanics model embedded into finite element method. The advanced numerical modelling adopts a Rankine and rotating crack material fracture model coupled to a non-linear analysis in an explicit finite element framework. The present study shows that the restorative materials currently used in non-carious cervical lesions are largely unsuitable in terms of resistance to fracture of the restoration and we suggest that the elastic modulus of such a material should be in the range of 1GPa. We anticipate that the presented methodology would provide more informative guidelines for the development of dental restorative materials, which could be tailored to specific clinical applications cognisant of the underlying mechanical environment.
Restoration of non-carious cervical lesions - Part I. Modelling of restorative fracture
Publisher: Elsevier BV
Date: 12-2007
DOI: 10.1016/J.DENTAL.2007.02.003
Abstract: As a typical non-carious cervical lesion, abfraction is a common clinical occurrence which requires restorative treatment in most patients. Nonetheless, the relatively poor clinical longevity of cervical dental used for restoring abfraction lesions has been a major concern of dentists and patients. The continuing loss of hard tissue and, in turn, the low retention of the restorative materials in situ motivates an in-depth exploration of the failure mechanism of the biomaterials involved. Despite considerable biomechanical relevance, conventional application of linear static finite element analysis (FEA) does not consider the fracture failure process, nor does it provide a quantitative predictive analysis for restorative design. This paper adopts a novel Rankine and rotating crack model to trace the fracture failure process of the cervical restorations. In contrast to the existing linear FEA, this study presents a nonlinear fracture analysis in an explicit finite element framework, which involves an automatic insertion of initial crack, mesh updating for crack propagation and self contact at the cracked interface. The results are in good agreement with published clinical data, in terms of the location of the fracture failure of the simulated restoration and the inadequacy of the dental restoratives for abfraction lesions. The success of the proposed model also demonstrates the potential for the monitoring and prediction of mechanical failure in other brittle biomaterials in a clinical situation.
On multiaxial failure behavior of closed-cell aluminum foams under medium strain rates
Publisher: Elsevier BV
Date: 03-2021
Robust optimization of foam-filled thin-walled structure based on sequential Kriging metamodel
Publisher: Springer Science and Business Media LLC
Date: 26-11-2013
Injury biomechanics-based nondeterministic optimization of front-end structures for safety in pedestrian–vehicle impact
Publisher: Elsevier BV
Date: 10-2021
Impact responses and residual flexural properties of narrow CFRP laminates
Publisher: Elsevier BV
Date: 05-2014
Lightweight hybrid materials and structures for energy absorption: A state-of-the-art review and outlook
Publisher: Elsevier BV
Date: 03-2022
Impaction loads resulting in intraoperative periprosthetic femoral fracture: A finite element study
Publisher: Trans Tech Publications, Ltd.
Date: 05-2014
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMM.553.299
Abstract: Intraoperative periprosthetic femoral fractures (IPPFF) occur in approximately 3-5% of all cementless total hip arthroplasty (THA) surgeries. This study aimed to identify the critical impaction load to cause an IPPFF during implant implementation. This critical load may be used as a guideline for surgeons as well as a parameter for the design of future surgical tools and procedures. This study concerned a single femur of a healthy 60 year old female with an anatomical femoral stem implant, thus the effects of patient specific variables (such as osteoporosis, amount of bone resorption, bone damage, implant geometry, age and gender) were not considered. The eXtended Finite Element Method (XFEM) was used to analyse the fracture. From CT scan data, a user-defined subroutine is used to assign heterogeneous isotropic material properties to the femur. It was computed that IPPFF would take place at an impaction load of 18.5 kN.
On characterization of cohesive zone model (CZM) based upon digital image correlation (DIC) method
Publisher: Elsevier BV
Date: 02-2022
Dual discriminative local coding for tissue aging analysis
Publisher: Elsevier BV
Date: 05-2017
DOI: 10.1016/J.MEDIA.2016.10.001
Abstract: In aging research, morphological age of tissue helps to characterize the effects of aging on different in iduals. While currently manual evaluations are used to estimate morphological ages under microscopy, such operation is difficult and subjective due to the complex visual characteristics of tissue images. In this paper, we propose an automated method to quantify morphological ages of tissues from microscopy images. We design a new sparse representation method, namely dual discriminative local coding (DDLC), that classifies the tissue images into different chronological ages. DDLC in- corporates discriminative distance learning and dual-level local coding into the basis model of locality-constrained linear coding thus achieves higher discriminative capability. The morphological age is then computed based on the classification scores. We conducted our study using the publicly avail- able terminal bulb aging database that has been commonly used in existing microscopy imaging research. To represent these images, we also design a highly descriptive descriptor that combines several complementary texture features extracted at two scales. Experimental results show that our method achieves significant improvement in age classification when compared to the existing approaches and other popular classifiers. We also present promising results in quantification of morphological ages.
Radial basis functional model for multi-objective sheet metal forming optimization
Publisher: Informa UK Limited
Date: 12-2011
Spatial correction of echo planar imaging deformation for subject specific diffusion tensor MRI analysis
Publisher: IEEE
Date: 12-2008
Multiobjective optimization of perforated square CFRP tubes for crashworthiness
Publisher: Elsevier BV
Date: 04-2020
Cuttlebone: Characterisation, Application and Development of Biomimetic Materials
Publisher: Springer Science and Business Media LLC
Date: 09-2012
On design optimization for structural crashworthiness and its state of the art
Publisher: Springer Science and Business Media LLC
Date: 16-09-2016
Dental implant induced bone remodeling and associated algorithms
Publisher: Elsevier BV
Date: 10-2009
DOI: 10.1016/J.JMBBM.2008.11.007
Abstract: Numerous studies have shown that human bone has the ability to remodel itself to better adapt to its biomechanical environment by changing both its material properties and geometry. As a consequence of the rapid development and extensive applications of dental implants, the effect of bone remodeling on the success of a dental restorative surgery is becoming critical for implant design and pre-surgical assessment. This article provides an extensive review on the issues of mandibular and maxillary bone remodeling as a result of dental implantation. Following the success of remodeling-driven orthopedic design from the long bone community, substantial clinical/experimental data of implantation have been driving the development of corresponding remodeling laws and algorithms to various dental settings, of which it is believed to contain potential to significantly impact on futuristic dental implant design. In this paper, the published remodeling data is analyzed and different biomechanical remodeling stimuli are assessed. The established relationships between bone density and corresponding mechanical properties are outlined and a range of potential methods of predicting the mandible and maxilla remodeling are critically evaluated and compared. It is anticipated that this will provide a better understanding of implant-induced bone remodeling and help develop a new design framework for patient-specific dental implantation.
Discrete sensitivity-based evolutionary design optimization
Publisher: Elsevier
Date: 2003
Topological configuration analysis and design for foam filled multi-cell tubes
Publisher: Elsevier BV
Date: 2018
Investigation on masticatory muscular functionality following oral reconstruction – An inverse identification approach
Publisher: Elsevier BV
Date: 06-2019
DOI: 10.1016/J.JBIOMECH.2019.04.007
Abstract: The human masticatory system has received significant attention in the areas of biomechanics due to its sophisticated co-activation of a group of masticatory muscles which contribute to the fundamental oral functions. However, determination of each muscular force remains fairly challenging in vivo the conventional data available may be inapplicable to patients who experience major oral interventions such as maxillofacial reconstruction, in which the resultant unsymmetrical anatomical structure invokes a more complex stomatognathic functioning system. Therefore, this study aimed to (1) establish an inverse identification procedure by incorporating the sequential Kriging optimization (SKO) algorithm, coupled with the patient-specific finite element analysis (FEA) in silico and occlusal force measurements at different time points over a course of rehabilitation in vivo and (2) evaluate muscular functionality for a patient with mandibular reconstruction using a fibula free flap (FFF) procedure. The results from this study proved the hypothesis that the proposed method is of certain statistical advantage of utilizing occlusal force measurements, compared to the traditionally adopted optimality criteria approaches that are basically driven by minimizing the energy consumption of muscle systems engaged. Therefore, it is speculated that mastication may not be optimally controlled, in particular for maxillofacially reconstructed patients. For the abnormal muscular system in the patient with orofacial reconstruction, the study shows that in general, the magnitude of muscle forces fluctuates over the 28-month rehabilitation period regardless of the decreasing trend of the maximum muscular capacity. Such finding implies that the reduction of the masticatory muscle activities on the resection side might lead to non-physiological oral biomechanical responses, which can change the muscular activities for stabilizing the reconstructed mandible.
Multiobjective optimization of multi-cell sections for the crashworthiness design
Publisher: Elsevier BV
Date: 11-2008
Topological design of all-ceramic dental bridges for enhancing fracture resistance
Publisher: Wiley
Date: 29-10-2016
DOI: 10.1002/CNM.2749
Abstract: Layered all-ceramic systems have been increasingly adopted in major dental prostheses. However, ceramics are inherently brittle, and they often subject to premature failure under high occlusion forces especially in the posterior region. This study aimed to develop mechanically sound novel topological designs for all-ceramic dental bridges by minimizing the fracture incidence under given loading conditions. A bi-directional evolutionary structural optimization (BESO) technique is implemented within the extended finite element method (XFEM) framework. Extended finite element method allows modeling crack initiation and propagation inside all-ceramic restoration systems. Following this, BESO searches the optimum distribution of two different ceramic materials, namely porcelain and zirconia, for minimizing fracture incidence. A performance index, as per a ratio of peak tensile stress to material strength, is used as a design objective. In this study, the novel XFEM based BESO topology optimization significantly improved structural strength by minimizing performance index for suppressing fracture incidence in the structures. As expected, the fracture resistance and factor of safety of fixed partial dentures structure increased upon redistributing zirconia and porcelain in the optimal topological configuration. Dental CAD/CAM systems and the emerging 3D printing technology were commercially available to facilitate implementation of such a computational design, exhibiting considerable potential for clinical application in the future. Copyright © 2015 John Wiley & Sons, Ltd.
Design optimization of scaffold microstructures using wall shear stress criterion towards regulated flow-induced erosion
Publisher: ASME International
Date: 08-2011
DOI: 10.1115/1.4004918
Abstract: Tissue scaffolds aim to provide a cell-friendly biomechanical environment for facilitating cell growth. Existing studies have shown significant demands for generating a certain level of wall shear stress (WSS) on scaffold microstructural surfaces for promoting cellular response and attachment efficacy. Recently, its role in shear-induced erosion of polymer scaffold has also drawn increasing attention. This paper proposes a bi-directional evolutionary structural optimization (BESO) approach for design of scaffold microstructure in terms of the WSS uniformity criterion, by downgrading highly-stressed solid elements into fluidic elements and/or upgrading lowly-stressed fluidic elements into solid elements. In addition to this, a computational model is presented to simulate shear-induced erosion process. The effective stiffness and permeability of initial and optimized scaffold microstructures are characterized by the finite element based homogenization technique to quantify the variations of mechanical properties of scaffold during erosion. The illustrative ex les show that a uniform WSS is achieved within the optimized scaffold microstructures, and their architectural and biomechanical features are maintained for a longer lifetime during shear-induced erosion process. This study provides a mathematical means to the design optimization of cellular biomaterials in terms of the WSS criterion towards controllable shear-induced erosion.
A time-dependent mechanobiology-based topology optimization to enhance bone growth in tissue scaffolds
Publisher: Elsevier BV
Date: 03-2021
Experimental study on the dynamic responses of foam sandwich panels with different facesheets and core gradients subjected to blast impulse
Publisher: Elsevier BV
Date: 2020
On twist springback in advanced high-strength steels
Publisher: Elsevier BV
Date: 06-2019
Parallelized optimization design of bumper systems under multiple low-speed impact loads
Publisher: Elsevier BV
Date: 10-2021
Lung image patch classification with automatic feature learning
Publisher: IEEE
Date: 07-2013
High-velocity impact behaviour of aluminium honeycomb sandwich panels with different structural configurations
Publisher: Elsevier BV
Date: 12-2018
A computational investigation into the impact resistance of a precise finite element model derived from micro-CT data of a woodpecker's head
Publisher: Elsevier BV
Date: 12-2020
Biofabrication: reappraising the definition of an evolving field
Publisher: IOP Publishing
Date: 08-01-2016
DOI: 10.1088/1758-5090/8/1/013001
Abstract: Biofabrication is an evolving research field that has recently received significant attention. In particular, the adoption of Biofabrication concepts within the field of Tissue Engineering and Regenerative Medicine has grown tremendously, and has been accompanied by a growing inconsistency in terminology. This article aims at clarifying the position of Biofabrication as a research field with a special focus on its relation to and application for Tissue Engineering and Regenerative Medicine. Within this context, we propose a refined working definition of Biofabrication, including Bioprinting and Bioassembly as complementary strategies within Biofabrication.
On crushing characteristics of different configurations of metal-composites hybrid tubes
Publisher: Elsevier BV
Date: 09-2017
Experimental and numerical investigation into the crashworthiness of metal-foam-composite hybrid structures
Publisher: Elsevier BV
Date: 02-2019
Characterization and design of 3D scaffolds for biofluidic criteria
Publisher: IEEE
Date: 05-2009
Role of implant configurations supporting three-unit fixed partial denture on mandibular bone response: biological-data-based finite element study
Publisher: Wiley
Date: 25-05-2016
DOI: 10.1111/JOOR.12411
Abstract: Implant-supported fixed partial denture with cantilever extension can transfer the excessive load to the bone around implants and stress/strain concentration potentially leading to bone resorption. This study investigated the effects of implant configurations supporting three-unit fixed partial denture (FPD) on the stress and strain distribution in the peri-implant bone by combining clinically measured time-dependent loading data and finite element (FE) analysis. A 3-dimensional mandibular model was constructed based on computed tomography (CT) images. Four different configurations of implants supporting 3-unit FPDs, namely three implant-supported FPD, conventional three-unit bridge FPD, distal cantilever FPD and mesial cantilever FPD, were modelled. The FPDs were virtually inserted to the molar area in the mandibular FE models. The FPDs were loaded according to time-dependent in vivo-measured 3-dimensional loading data during chewing. The von Mises stress (VMS) and equivalent strain (EQS) in peri-implant bone regions were evaluated as mechanical stimuli. During the chewing cycles, the regions near implant necks and bottom apexes experienced high VMS and EQS than the middle regions in all implant-supported FPD configurations. Higher VMS and EQS values were also observed at the implant neck region adjacent to the cantilever extension in the cantilevered configurations. The patient-specific dynamic loading data and CT-based reconstruction of full 3D mandibular allowed us to model the biomechanical responses more realistically. The results provided data for clinical assessment of implant configuration to improve longevity and reliability of the implant-supported FPD restoration.
Stress based optimization of torsional shafts using an evolutionary procedure
Publisher: Elsevier BV
Date: 08-2001
Phase field fracture in elasto-plastic solids: Variational formulation for multi-surface plasticity and effects of plastic yield surfaces and hardening
Publisher: Elsevier BV
Date: 06-2019
Monitoring natural frequency for osseointegration and bone remodeling induced by dental implants
Publisher: IEEE
Date: 05-2009
On design for additive manufacturing (DAM) parameter and its effects on biomechanical properties of 3D printed ceramic scaffolds
Publisher: Elsevier BV
Date: 06-2020
Design of cellular porous biomaterials for wall shear stress criterion
Publisher: Wiley
Date: 13-09-2010
DOI: 10.1002/BIT.22842
Abstract: The microfluidic environment provided by implanted prostheses has a decisive influence on the viability, proliferation and differentiation of cells. In bone tissue engineering, for instance, experiments have confirmed that a certain level of wall shear stress (WSS) is more advantageous to osteoblastic differentiation. This paper proposes a level-set-based topology optimization method to regulate fluidic WSS distribution for design of cellular biomaterials. The topological boundary of fluid phase is represented by a level-set model embedded in a higher-dimensional scalar function. WSS is determined by the computational fluid dynamics analysis in the scale of cellular base cells. To achieve a uniform WSS distribution at the solid-fluid interface, the difference between local and target WSS is taken as the design criterion, which determines the speed of the boundary evolution in the level-set model. The ex les demonstrate the effectiveness of the presented method and exhibit a considerable potential in the design optimization and fabrication of new prosthetic cellular materials for bioengineering applications.
Crashworthiness design for functionally graded foam-filled thin-walled structures
Publisher: Elsevier BV
Date: 03-2010
On lateral compression of circular aluminum, CFRP and GFRP tubes
Publisher: Elsevier BV
Date: 2020
Micro-CT based modelling for characterising injection-moulded porous titanium implants
Publisher: Wiley
Date: 13-04-2017
DOI: 10.1002/CNM.2779
Abstract: Design of prosthetic implants to ensure rapid and stable osseointegration remains a significant challenge, and continuous efforts have been directed to new implant materials, structures and morphology. This paper aims to develop and characterise a porous titanium dental implant fabricated by metallic powder injection-moulding. The surface morphology of the specimens was first examined with a scanning electron microscope (SEM), followed by microscopic computerised tomography (μ-CT) scanning to capture its 3D microscopic features non-destructively. The nature of porosity and pore sizes were determined statistically. A homogenisation technique based on the Hills-energy theorem was adopted to evaluate its directional elastic moduli, and the conservation of mass theorem was employed to quantify the oxygen diffusivity for bio-transportation feature. This porous medium was found to have pore sizes varying from 50 to 400 µm and the average porosity of 46.90 ± 1.83%. The anisotropic principal elastic moduli were found fairly close to the upper range of cortical bone, and the directional diffusivities could potentially enable radial osseous tissue ingrowth and vascularisation. This porous titanium successfully reduces the elastic modulus mismatch between implant and bone for dental and orthopaedic applications, and provides improved capacity for transporting oxygen, nutrient and waste for pre-vascular network formation. Copyright © 2016 John Wiley & Sons, Ltd.
Microstructure design of biodegradable scaffold and its effect on tissue regeneration
Publisher: Elsevier BV
Date: 08-2011
DOI: 10.1016/J.BIOMATERIALS.2011.03.064
Abstract: Biodegradable scaffolds play a critical role in therapeutic tissue engineering, in which the matrix degradation and tissue ingrowth are of particular importance for determining the ongoing performance of tissue-scaffold system during regenerative process. This paper aims to explore the mechanobiological process within biodegradable scaffolds, where the representative volume element (RVE) is extracted from periodic scaffold micro-architectures as a base-cell design model. The degradation of scaffold matrix is modeled in terms of a stochastic hydrolysis process enhanced by diffusion-controlled autocatalysis and the tissue ingrowth is modeled through the mechano-regulatory theory. By using the finite element based homogenization technique and topology optimization approach, the effective properties of various periodic scaffold structures are obtained. To explore the effect of scaffold design on the mechanobiological evolutions of tissue-scaffold systems, different scaffold architectures are considered for polymer degradation and tissue regeneration. It is found that the different tissues can grow into the degraded voids inside the polymer matrix. It is demonstrated that the design of scaffold architecture has a considerable impact on the tissue regeneration outcome, which exhibits the importance of implementing different criteria in scaffold micro-structural design, before being fabricated via rapid prototyping technique, e.g. solid free-form fabrication (SFF). This study models such an interactive process of scaffold degradation and tissue growth, thereby providing some new insights into design of biodegradable scaffold micro-architecture for tissue engineering.
Energy absorption mechanics and design optimization of CFRP/aluminium hybrid structures for transverse loading
Publisher: Elsevier BV
Date: 2019
Investigating size effects of complex nanostructures through Young-Laplace equation and finite element analysis
Publisher: AIP Publishing
Date: 23-11-2015
DOI: 10.1063/1.4935819
Abstract: Analytical studies on the size effects of a simply-shaped beam fixed at both ends have successfully explained the sudden changes of effective Young's modulus as its diameter decreases below 100 nm. Yet they are invalid for complex nanostructures ubiquitously existing in nature. In accordance with a generalized Young-Laplace equation, one of the representative size effects is transferred to non-uniformly distributed pressure against an external surface due to the imbalance of inward and outward loads. Because the magnitude of pressure depends on the principal curvatures, iterative steps have to be adopted to gradually stabilize the structure in finite element analysis. Computational results are in good agreement with both experiment data and theoretical prediction. Furthermore, the investigation on strengthened and softened Young's modulus for two complex nanostructures demonstrates that the proposed computational method provides a general and effective approach to analyze the size effects for nanostructures in arbitrary shape.
The relationship of mandibular morphology with residual ridge resorption associated with implant-retained overdentures
Publisher: Quintessence Publishing
Date: 11-2016
DOI: 10.11607/IJP.4726
Abstract: The objective of this clinical study was to determine the relationship of mandibular morphology with residual ridge resorption (RRR) of implant-retained overdenture (IRO) patients. RRR was quantified as change in bone volume over 1- and 2-year periods using cone beam computed tomography and a medical imaging program. Features of the mandibular morphology, namely the gonial angle, ramus length, ramus width, corpus length, and corpus height, were measured on three-dimensional models and correlated to the RRR. A total of 25 participants were treated with mandibular IROs opposing maxillary complete dentures. By the 2-year follow-up, radiographic data for 18 patients were complete for analysis. Of these 18 participants, half fall into the low gonial angle category and the other half into the high angle. The extent of RRR was highly variable among participants and ranged from -2 to +2 mm in depth over the 2-year period. The mean decrease in bone volume after the first year was 3.8 ± 4.5%. This rate decreased to 3.2 ± 4.1% after the second year. RRR occurs either by translation of the entire thickness of cortical layer apically or by thinning of the outer cortical layer. RRR was significantly correlated to gonial angle (r = .471 P = .048) and predominantly occurred in the molar region in low-angle participants and more anteriorly in high-angle participants. There was no association between RRR and ramus length (r = -.341 P = .166), ramus width (r = -.183 P =.468), corpus length (r = .057 P = .821), and corpus height (r = .097 P = .702). Within the limitations of this study, it may be concluded that gonial angle is significantly related to RRR associated with IROs.
Reduced energy offset via substitutional doping for efficient organic/inorganic hybrid solar cells
Publisher: The Optical Society
Date: 09-04-2015
DOI: 10.1364/OE.23.00A444
Load bearing and failure characteristics of perforated square CFRP tubes under axial crushing
Publisher: Elsevier BV
Date: 2017
Modal identification of vibrating structures using singular value decomposition and nonlinear iteration based on high-speed digital image correlation
Publisher: Elsevier BV
Date: 06-2021
Development of HEATHER for Cochlear Implant Stimulation Using a New Modeling Workflow
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 02-2015
Mechanobiological bone reaction quantified by positron emission tomography
Publisher: SAGE Publications
Date: 20-02-2015
Abstract: While nuclear medicine has been proven clinically effective for examination of the change in bone turnover as a result of stress injury, quantitative correlation between tracer uptake and mechanical stimulation in the human jawbone remains unclear. This study aimed to investigate the relationship between bone metabolism observed by 18F-fluoride positron emission tomography (PET) images and mechanical stimuli obtained by finite element analysis (FEA) in the residual ridge induced by the insertion of a removable partial denture (RPD). An 18F-fluoride PET/CT (computerized tomography) scan was performed to assess the change of bone metabolism in the residual ridge under the denture before and after RPD treatment. Corresponding patient-specific 3D finite element (FE) models were created from CT images. Boundary conditions were prescribed by the modeling of condylar contacts, and muscular forces were derived from the occlusal forces measured in vivo to generate mechanobiological reactions. Different mechanobiological stimuli, e.g., equivalent von Mises stress (VMS), equivalent strain (EQV), and strain energy density (SED), determined from nonlinear FEA, were quantified and compared with the standardized uptake values (SUVs) of PET. Application of increased occlusal force after RPD insertion induced higher mechanical stimuli in the residual bone. Accordingly, SUV increased in the region of residual ridge with higher mechanical stimuli. Thus, with SUV, a clear correlation was observed with VMS and SED in the cancellous bone, especially after RPD insertion (R 2 0.8, P 0.001). This study revealed a good correlation between bone metabolism and mechanical stimuli induced by RPD insertion. From this patient-specific study, it was shown that metabolic change detected by PET in the loaded bone, in a much shorter duration than conventional x-ray assessment, is associated with mechanical stimuli. The nondestructive nature of PET/CT scans and FEA could potentially provide a new method for clinical examination and monitoring of prosthetically driven bone remodeling.
Computational biomechanics of bone's responses to dental prostheses – osseointegration, remodeling and resorption
Publisher: IOP Publishing
Date: 06-2010
Crashworthiness of vertex based hierarchical honeycombs in out-of-plane impact
Publisher: Elsevier BV
Date: 11-2016
Crash responses under multiple impacts and residual properties of CFRP and aluminum tubes
Publisher: Elsevier BV
Date: 06-2018
Computational design analysis for deployment of cardiovascular stents
Publisher: IOP Publishing
Date: 06-2010
Crashworthiness design of a steel–aluminum hybrid rail using multi-response objective-oriented sequential optimization
Publisher: Elsevier BV
Date: 10-2017
Characterization of cuttlebone for a biomimetic design of cellular structures
Publisher: Springer Science and Business Media LLC
Date: 12-11-2010
Effects of design parameters on fracture resistance of glass simulated dental crowns
Publisher: Elsevier BV
Date: 03-2016
DOI: 10.1016/J.DENTAL.2015.11.018
Abstract: This study aimed to in idually quantify the effects of various design parameters, including margin thickness, convergence angle of abutment, and bonding conditions on fracture resistance of resin bonded glass dental crown systems (namely, glass simulated crown). An in vitro experimental test and an in silico computational eXtended Finite Element Method (XFEM) were adopted to explore crack initiation and propagation in glass simulated crown models with the margin thickness ranging from 0.8 to 1.2mm, convergence angle from 6° to 12°, and three different bonding conditions, namely non-bonded (NB), partially bonded (PB), fully bonded (FB). The XFEM modeling results of cracking initiation loads and subsequent growth in the glass simulated crown models were correlated with the experimental results. It was found that the margin thickness has a more significant effect on the fracture resistance than the convergence angle. The adhesively bonded state has the highest fracture resistance among these three different bonding conditions. Crowns with thicker margins, smaller convergence angle and fully bonded are recommended for increasing fracture resistance of all-ceramic crowns. This numerical modeling study, supported by the experimental tests, provides more thorough mechanical insight into the role of margin design parameters, thereby forming a novel basis for clinical guidance as to preparation of tapered abutments for all-ceramic dental crowns.
Incorporating vascular structure into electric volume conduction models of the cochlea
Publisher: IEEE
Date: 12-2012
Prediction of mandibular bone remodelling induced by fixed partial dentures
Publisher: Elsevier BV
Date: 06-2010
DOI: 10.1016/J.JBIOMECH.2010.02.016
Abstract: Fixed partial dentures (FPD) or dental bridges have been extensively utilised in prosthodontic restoration. Despite considerable clinical success to date, there has been limited fundamental understanding of the biomechanical consequences induced by FPD treatment. It is noted that FPD construction significantly alters the biological and mechanical environment in the supporting bone region. Thus, the surrounding bones will be engaged to adapt to such a biomechanical change. This paper aims to address this critical issue by developing a new remodelling procedure induced by FPD restoration. Specifically, it relates the mechanical stimulus to the change in Hounsfield Unit (HU) value in terms of surface area density (SAD) of bony morphology, which allows direct correlation to clinical computerised tomography (CT) data. The procedure will provide prosthodontist with a new approach for assessing FPD treatment, thereby optimising FPD design for improving longevity and reliability of future FPD restoration.
Multicriteria optimization that minimizes maximum stress and maximizes stiffness
Publisher: Elsevier BV
Date: 11-2021
An evolutionary shape optimization for elastic contact problems subject to multiple load cases
Publisher: Elsevier BV
Date: 08-2005
Biomechanical optimization of subject-specific implant positioning for femoral head resurfacing to reduce fracture risk
Publisher: SAGE Publications
Date: 19-04-2016
Abstract: Peri-prosthetic femoral neck fracture after femoral head resurfacing can be either patient-related or surgical technique-related. The study aimed to develop a patient-specific finite element modelling technique that can reliably predict an optimal implant position and give minimal strain in the peri-prosthetic bone tissue, thereby reducing the risk of peri-prosthetic femoral neck fracture. The subject-specific finite element modelling was integrated with optimization techniques including design of experiments to best possibly position the implant for achieving minimal strain for femoral head resurfacing. S le space was defined by varying the floating point to find the extremes at which the cylindrical reaming operation actually cuts into the femoral neck causing a notch during hip resurfacing surgery. The study showed that the location of the maximum strain, for all non-notching positions, was on the superior femoral neck, in the peri-prosthetic bone tissue. It demonstrated that varus positioning resulted in a higher strain, while valgus positioning reduced the strain, and further that neutral version had a lower strain.
CD103+ Dendritic Cells Elicit CD8+ T Cell Responses to Accelerate Kidney Injury in Adriamycin Nephropathy
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 16-09-2015
Abstract: CD103 + dendritic cells (DCs) in nonlymphoid organs exhibit two main functions: maintaining tolerance by induction of regulatory T cells and protecting against tissue infection through cross-presentation of foreign antigens to CD8 + T cells. However, the role of CD103 + DCs in kidney disease is unknown. In this study, we show that CD103 + DCs are one of four subpopulations of renal mononuclear phagocytes in normal kidneys. CD103 + DCs expressed DC-specific surface markers, transcription factors, and growth factor receptors and were found in the kidney cortex but not in the medulla. The number of kidney CD103 + DCs was significantly higher in mice with adriamycin nephropathy (AN) than in normal mice, and depletion of CD103 + DCs attenuated kidney injury in AN mice. In vitro , kidney CD103 + DCs preferentially primed CD8 + T cells and did not directly induce tubular epithelial cell apoptosis. Adoptive transfer of CD8 + T cells significantly exacerbated kidney injury in AN SCID mice, whereas depletion of CD103 + DCs in these mice impaired activation and proliferation of transfused CD8 + T cells and prevented the exacerbation of kidney injury associated with this transfusion. In conclusion, kidney CD103 + DCs display a pathogenic role in murine CKD via activation of CD8 + T cells.
A finite element investigation into the effects of head size and trunnion design on the micromotion at the head-neck interface in THR
Publisher: Trans Tech Publications, Ltd.
Date: 05-2014
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMM.553.287
Abstract: The modularity of femoral head and femoral stem provides many benefits to surgeons. However, case-reports have shown failure in large head Metal-on-Metal hip replacement due to trunnionosis. The exact causes of trunnionosis are not yet identified but the additional interface at the modular joint seems to be a contributing factor. In this study, a three dimensional non-linear finite element model was created to analyse the effects of head size and trunnion design on the micromotion at the head-neck interface. Four different metal head sizes and two trunnions designs and materials were used in the model. The femoral heads were assembled onto the trunnions with 7kN axial force and one cycle of gait load was applied to the head after assembly. The study showed that the micromotion was substantially increased in femoral head larger than 36mm. Trunnions material has greater effect on micromotion than trunnion design, particularly with the larger head sizes. The stability at the modular junction is important. Our findings suggest that there is a limit of assembly force to maintain enough stability on the joint beyond this limit the maximum micromotion will not be affected.
Experimental investigation into transverse crashworthiness of CFRP adhesively bonded joints in vehicle structure
Publisher: Elsevier BV
Date: 12-2013
Machine learning based topology optimization of fiber orientation for variable stiffness composite structures
Publisher: Wiley
Date: 09-2021
DOI: 10.1002/NME.6809
Abstract: This study proposes a machine learning (ML) based approach for optimizing fiber orientations of variable stiffness carbon fiber reinforced plastic (CFRP) structures, where neural networks are developed to estimate the objective function and analytical sensitivities with respect to design variables as a substitute for finite element analysis (FEA). To reduce the number of training s les and improve the regression accuracy, an active learning strategy is implemented by successively supplying effective s les along with the suboptimal process. After proper training of neural networks, a quasi‐global search strategy can be applied by implementing a large number of initial designs as starting points in the optimization. In this article, a mathematical ex le is first presented to show the superiority of the active learning strategy. Then a benchmark design ex le of a CFRP plate is scrutinized to compare the proposed ML‐based with the conventional FEA‐based discrete material optimization (DMO) method. Finally, topology optimization of fiber orientations is performed for design of a CFRP engine hood, in which the structural performance generated from the proposed ML‐based approach achieves 12.62% improvement compared with that obtained from the conventional single‐initial design method. This article is anticipated to demonstrate a new alternative for design of fiber‐reinforced composite structures.
Shape optimization for additive manufacturing of removable partial dentures - A new paradigm for prosthetic CAD/CAM
Publisher: Public Library of Science (PLoS)
Date: 10-07-2015
Experimental investigation into dynamic axial impact responses of double hat shaped CFRP tubes
Publisher: Elsevier BV
Date: 09-2015
A periodontal ligament driven remodeling algorithm for orthodontic tooth movement
Publisher: Elsevier BV
Date: 05-2014
DOI: 10.1016/J.JBIOMECH.2014.02.030
Abstract: While orthodontic tooth movement (OTM) gains considerable popularity and clinical success, the roles played by relevant tissues involved, particularly periodontal ligament (PDL), remain an open question in biomechanics. This paper develops a soft-tissue induced external (surface) remodeling procedure in a form of power law formulation by correlating time-dependent simulation in silico with clinical data in vivo (p<0.05), thereby providing a systematic approach for further understanding and prediction of OTM. The biomechanical stimuli, namely hydrostatic stress and displacement vectors experienced in PDL, are proposed to drive tooth movement through an iterative hyperelastic finite element analysis (FEA) procedure. This algorithm was found rather indicative and effective to simulate OTM under different loading conditions, which is of considerable potential to predict therapeutical outcomes and develop a surgical plan for sophisticated orthodontic treatment.
Evolutionary topology optimization of periodic composites for extremal magnetic permeability and electrical permittivity
Publisher: Springer Science and Business Media LLC
Date: 31-01-2012
Discrete topology optimization of ply orientation for a carbon fiber reinforced plastic (CFRP) laminate vehicle door
Publisher: Elsevier BV
Date: 08-2017
Topology optimization for negative permeability metamaterials using level-set algorithm
Publisher: Elsevier BV
Date: 04-2011
Multiobjective robust optimization method for drawbead design in sheet metal forming
Publisher: Elsevier BV
Date: 04-2010
Time-domain finite element models of electrochemistry in intracochlear electrodes
Publisher: IEEE
Date: 07-2013
Buckling-induced retraction of structured spherical shell under pressure
Publisher: Trans Tech Publications, Ltd.
Date: 05-2014
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMM.553.842
Abstract: This paper investigates the reversible retraction of a spherical perforated shell that is made from nonlinear soft material. The buckling and post-buckling simulation in Abaqus shows the skeleton ligaments of such a buckliball rotate in the beginning and buckle thereafter, resulting in the shrinkage and encapsulation of the whole structure in the final stage. We used dynamic-explicit method in the simulation and its superiority over others is verified by obtaining correct buckling patterns efficiently and stably.
Design optimization of functionally graded dental implant for bone remodeling
Publisher: Elsevier BV
Date: 10-2009
On low-velocity impact response of foam-core sandwich panels
Publisher: Elsevier BV
Date: 09-2020
Structural topology design with multiple thermal criteria
Publisher: Emerald
Date: 09-2000
DOI: 10.1108/02644400010340642
Abstract: This paper shows how the evolutionary structural optimization (ESO) algorithm can be used to achieve a multiple criterion design for a structure in a thermal environment. The proposed thermal ESO procedure couples an evolutionary iterative process of a finite element heat conduction solution and a finite element thermoelastic solution. The overall efficiency of material usage is measured in terms of the combination of thermal stress levels and heat flux densities by using a combination strategy with weighting factors. The ESO method then works by eliminating from the structural domain under‐utilized material. In this paper, a practical design ex le of a printed circuit board substrate is presented to illustrate the capabilities of the ESO algorithm for thermal design optimization in multiple load environments.
Residual crashworthiness of CFRP structures with pre-impact damage – An experimental and numerical study
Publisher: Elsevier BV
Date: 12-2018
A Novel Bone Substitute with High Bioactivity, Strength, and Porosity for Repairing Large and Load-Bearing Bone Defects
Publisher: Wiley
Date: 18-02-2019
Abstract: Achieving adequate healing in large or load-bearing bone defects is highly challenging even with surgical intervention. The clinical standard of repairing bone defects using autografts or allografts has many drawbacks. A bioactive ceramic scaffold, strontium-hardystonite-gahnite or "Sr-HT-Gahnite" (a multi-component, calcium silicate-based ceramic) is developed, which when 3D-printed combines high strength with outstanding bone regeneration ability. In this study, the performance of purely synthetic, 3D-printed Sr-HT-Gahnite scaffolds is assessed in repairing large and load-bearing bone defects. The scaffolds are implanted into critical-sized segmental defects in sheep tibia for 3 and 12 months, with bone autografts used for comparison. The scaffolds induce substantial bone formation and defect bridging after 12 months, as indicated by X-ray, micro-computed tomography, and histological and biomechanical analyses. Detailed analysis of the bone-scaffold interface using focused ion beam scanning electron microscopy and multiphoton microscopy shows scaffold degradation and maturation of the newly formed bone. In silico modeling of strain energy distribution in the scaffolds reveal the importance of surgical fixation and mechanical loading on long-term bone regeneration. The clinical application of 3D-printed Sr-HT-Gahnite scaffolds as a synthetic bone substitute can potentially improve the repair of challenging bone defects and overcome the limitations of bone graft transplantation.
Smoothed finite element method with exact solutions in heat transfer problems
Publisher: Elsevier BV
Date: 11-2014
A comparative mechanical and bone remodelling study of all-ceramic posterior inlay and onlay fixed partial dentures
Publisher: Elsevier BV
Date: 2012
DOI: 10.1016/J.JDENT.2011.10.003
Abstract: Comparative studies of bone remodelling and mechanical stresses between inlay and onlay fixed partial dentures (FPD) are rather limited. The purpose of this paper was to evaluate the biological consequence in posterior mandibular bone and the mechanical responses in these two different prosthetic configurations. Three-dimensional (3D) finite element analysis (FEA) models are created to explore the mechanical responses for the inlay and onlay preparations within the same oral environment. Strain induced bone remodelling was simulated under mastication. The remodelling adopted herein relates the strain in the bone to the change of Hounsfield Unit (HU) value in proportion to the surface area density (SAD) of bony morphology, which allows directly correlating to clinical computerised tomography (CT) data. The results show that both FPD designs exhibit a similar resultant change in bone mineral density (BMD) though the onlay configuration leads to a more uniform distribution of bone density. The inlay design results in higher mechanical stresses whilst allowing preservation of healthy tooth structure. This study provides an effective means to further clinical assessment and investigation into biomechanical responses and long-term restorative outcome with different FPD designs. Quantifying in vivo stress distributions associated with inlay/onlay FPDs can further supplement clinical investigations into prosthetic durability, FPD preparation techniques (i.e., taper angles, material development), consequent stress distributions and the ongoing biomechanical responses of mandibular bone.
Smoothed finite element method for topology optimization involving incompressible materials
Publisher: Informa UK Limited
Date: 06-04-2016
A Preoperative Analytical Model for Patient-Specific Impingement Analysis in Total Hip Arthroplasty
Publisher: Hindawi Limited
Date: 07-2019
DOI: 10.1155/2019/6293916
Abstract: Prosthetic impingement is important to consider during total hip arthroplasty planning to minimise the risk of joint instability. Modelling impingement preoperatively can assist in defining the required component alignment for each in idual. We developed an analytical impingement model utilising a combination of mathematical calculations and an automated computational simulation to determine the risk of prosthetic impingement. The model assesses cup inclination and anteversion angles that are associated with prosthetic impingement using patient-specific inputs, such as stem anteversion, planned implant types, and target Range of Motion (ROM). The analysed results are presented as a range of cup inclination and anteversion angles over which a colour map indicates an impingement-free safe zone in green and impingement risk zones in red. A validation of the model demonstrates accuracy within +/- 1.4° of cup inclination and anteversion. The study further investigated the impact of changes in stem anteversion, femoral head size, and head offset on prosthetic impingement, as an ex le of the application of the model.
Crashworthiness design of vehicle by using multiobjective robust optimization
Publisher: Springer Science and Business Media LLC
Date: 24-12-2010
Fracture behavior of inlay and onlay fixed partial dentures - An in-vitro experimental and XFEM modeling study
Publisher: Elsevier BV
Date: 06-2016
DOI: 10.1016/J.JMBBM.2016.01.035
Abstract: This study aimed to explore the "sensitivity" of the fracture load and initiation site to loading position on the central occlusal surface of a pontic tooth for both all-ceramic inlay retained and onlay supported partial denture systems. Three dimensional (3D) finite element (FE) inlay retained and onlay supported partial denture models were established for simulating crack initiation and propagation by using the eXtended Finite Element Method (XFEM). The models were subjected to a mastication force up to 500N on the central fossa of the pontic. The loading position was varied to investigate its influence on fracture load and crack path. Small perturbation of the loading position caused the fracture load and crack pattern to vary considerably. For the inlay fixed partial dentures (FPDs), the fracture origins changed from the bucco-gingival aspect of the molar embrasure to the premolar embrasure when the indenter force location is slightly shifted from the mesial to distal side. In contrast, for onlay FPDs, cracking initiated from bucco-gingival aspect of the premolar embrasure when the indenter is slightly shifted to the buccal side and from molar embrasure when the indenter is shifted to the lingual side. The fracture load and cracking path were found to be very sensitive to loading position in the all-ceramic inlay and onlay FPDs. The study provides a basis for improved understanding on the role of localized contact loading of the cusp surface in all-ceramic FPDs.
Crashworthiness optimization of corrugated sandwich panels
Publisher: Elsevier BV
Date: 10-2013
On stiffness of scaffolds for bone tissue engineering-a numerical study
Publisher: Elsevier BV
Date: 06-2010
DOI: 10.1016/J.JBIOMECH.2010.02.020
Abstract: Tissue scaffolds are typically designed and fabricated to match native bone properties. However, it is unclear if this would lead to the best tissue ingrowth outcome within the scaffold as neo-tissue keeps changing the stiffness of entire construct. This paper presents a numerical method to address this issue for design optimization and assessment of tissue scaffolds. The elasticity tensors of two different types of bones are weighted by different multipliers before being used as the targets in scaffold design. A cost function regarding the difference between the effective elasticity tensor, calculated by the homogenization technique, and the target tensor, is minimized by using topology optimization procedure. It is found that different stiffnesses can lead to different remodeling results. The comparison confirms that bone remodeling is at its best when the scaffold elastic tensor matches or is slightly higher than the elastic properties of the host bone.
A new multi-objective discrete robust optimization algorithm for engineering design
Publisher: Elsevier BV
Date: 2018
Lightweight design of carbon twill weave fabric composite body structure for electric vehicle
Publisher: Elsevier BV
Date: 03-2013
Towards automated 3D finite element modeling of direct fiber reinforced composite dental bridge
Publisher: Wiley
Date: 23-05-2005
DOI: 10.1002/JBM.B.30233
Abstract: An automated 3D finite element (FE) modeling procedure for direct fiber reinforced dental bridge is established on the basis of computer tomography (CT) scan data. The model presented herein represents a two-unit anterior cantilever bridge that includes a maxillary right incisor as an abutment and a maxillary left incisor as a cantilever pontic bonded by adhesive and reinforced fibers. The study aims at gathering fundamental knowledge for design optimization of this type of innovative composite dental bridges. To promote the automatic level of numerical analysis and computational design of new dental biomaterials, this report pays particular attention to the mathematical modeling, mesh generation, and validation of numerical models. To assess the numerical accuracy and to validate the model established, a convergence test and experimental verification are also presented.
Multiobjective robust optimization of coronary stents
Publisher: Elsevier BV
Date: 2016
A comparative study on complete and implant retained denture treatments - A biomechanics perspective
Publisher: Elsevier BV
Date: 02-2015
DOI: 10.1016/J.JBIOMECH.2014.11.043
Abstract: Although implant-retained overdenture allows edentulous patients to take higher occlusal forces than the conventional complete dentures, the biomechanical influences have not been explored yet. Clinically, there is limited knowledge and means for predicting localized bone remodelling after denture treatment with and without implant support. By using finite element (FE) analysis, this article provides an in-silico approach to exploring the treatment effects on the oral mucosa and potential resorption of residual ridge under three different denture configurations in a patient-specific manner. Based on cone beam computerized tomography (CBCT) scans, a 3D heterogeneous FE model was created and the supportive tissue, mucosa, was characterized as a hyperelastic material. A measured occlusal load (63N) was applied onto three virtual models, namely complete denture, two and four implant-retained overdentures. Clinically, the bone resorption was measured after one year in the two implant-retained overdenture treatment. Despite the improved stability and enhanced masticatory function, the implant-retained overdentures demonstrated higher hydrostatic stress in mucosa (43.6kPa and 39.9kPa for two and four implants) at the posterior ends of the mandible due to the cantilever effect, than the complete denture (33.4kPa). Hydrostatic pressure in the mucosa signifies a critical indicator and can be correlated with clinically measured bone resorption, pointing to severer mandibular ridge resorption posteriorly with implant-retained overdentures. This study provides a biomechanical basis for denture treatment planning to improve long-term outcomes with minimal residual ridge resorption.
Implicit Integration of the Unified Yield Criterion in the Principal Stress Space
Publisher: American Society of Civil Engineers (ASCE)
Date: 07-2019
Dynamic response of sandwich panel with hierarchical honeycomb cores subject to blast loading
Publisher: Elsevier BV
Date: 09-2019
Bone remodeling following mandibular reconstruction using fibula free flap
Publisher: Elsevier BV
Date: 03-2022
DOI: 10.1016/J.JBIOMECH.2022.110968
Abstract: To investigate bone remodelling responses to mandibulectomy, a joint external and internal remodelling algorithm is developed here by incorporating patient-specific longitudinal data. The primary aim of this study is to simulate bone remodelling activity in the conjunction region with a fibula free flap (FFF) reconstruction by correlating with a 28-month clinical follow-up. The secondary goal of this study is to compare the long-term outcomes of different designs of fixation plate with specific screw positioning. The results indicated that the overall bone density decreased over time, except for the Docking Site (namely DS1, a region of interest in mandibular symphysis with the conjunction of the bone union), in which the decrease of bone density ceased later and was followed by bone apposition. A negligible influence on bone remodeling outcome was found for different screw positioning. This study is believed to be the first of its kind for computationally simulating the bone turn-over process after FFF maxillofacial reconstruction by correlating with patient-specific follow-up.
Fracture behaviors of ceramic tissue scaffolds for load bearing applications
Publisher: Springer Science and Business Media LLC
Date: 12-07-2016
DOI: 10.1038/SREP28816
Abstract: Healing large bone defects, especially in weight-bearing locations, remains a challenge using available synthetic ceramic scaffolds. Manufactured as a scaffold using 3D printing technology, Sr-HT-Gahnite at high porosity (66%) had demonstrated significantly improved compressive strength (53 ± 9 MPa) and toughness. Nevertheless, the main concern of ceramic scaffolds in general remains to be their inherent brittleness and low fracture strength in load bearing applications. Therefore, it is crucial to establish a robust numerical framework for predicting fracture strengths of such scaffolds. Since crack initiation and propagation plays a critical role on the fracture strength of ceramic structures, we employed extended finite element method (XFEM) to predict fracture behaviors of Sr-HT-Gahnite scaffolds. The correlation between experimental and numerical results proved the superiority of XFEM for quantifying fracture strength of scaffolds over conventional FEM. In addition to computer aided design (CAD) based modeling analyses, XFEM was conducted on micro-computed tomography (μCT) based models for fabricated scaffolds, which took into account the geometric variations induced by the fabrication process. Fracture strengths and crack paths predicted by the μCT-based XFEM analyses correlated well with relevant experimental results. The study provided an effective means for the prediction of fracture strength of porous ceramic structures, thereby facilitating design optimization of scaffolds.
Tooth Eruption Results from Bone Remodelling Driven by Bite Forces Sensed by Soft Tissue Dental Follicles: A Finite Element Analysis
Publisher: Public Library of Science (PLoS)
Date: 15-03-2013
An experimental and numerical study on quasi-static and dynamic crashing behaviors for tailor rolled blank (TRB) structures
Publisher: Elsevier BV
Date: 03-2017
Effect of fully porous-coated (FPC) technique on osseointegration of dental implants
Publisher: Trans Tech Publications Ltd.
Date: 09-02-2008
A level-set procedure for the design of electromagnetic metamaterials
Publisher: Optica Publishing Group
Date: 17-03-2010
DOI: 10.1364/OE.18.006693
Thermally induced fracture for core-veneered dental ceramic structures
Publisher: Elsevier BV
Date: 09-2013
DOI: 10.1016/J.ACTBIO.2013.05.009
Abstract: Effective and reliable clinical uses of dental ceramics necessitate an insightful analysis of the fracture behaviour under critical conditions. To better understand failure characteristics of porcelain veneered to zirconia core ceramic structures, thermally induced cracking during the cooling phase of fabrication is studied here by using the extended finite element method (XFEM). In this study, a transient thermal analysis of cooling is conducted first to determine the temperature distributions. The time-dependent temperature field is then imported to the XFEM model for viscoelastic thermomechanical analysis, which predicts thermally induced damage and cracking at different time steps. Temperature-dependent material properties are used in both transient thermal and thermomechanical analyses. Three typical ceramic structures are considered in this paper, namely bi-layered spheres, squat cylinders and dental crowns with thickness ratios of either 1:2 or 1:1. The XFEM fracture patterns exhibit good agreement with clinical observation and the in vitro experimental results obtained from scanning electron microscopy characterization. The study reveals that fast cooling can lead to thermal fracture of these different bi-layered ceramic structures, and cooling rate (in terms of heat transfer coefficient) plays a critical role in crack initiation and propagation. By exploring different cooling rates, the heat transfer coefficient thresholds of fracture are determined for different structures, which are of clear clinical implication.
Effect of scaffold architecture on tissue regeneration
Publisher: Springer Berlin Heidelberg
Date: 2010
Topology optimization for periodic multi-component structures with stiffness and frequency criteria
Publisher: Springer Science and Business Media LLC
Date: 20-02-2020
Theoretical, numerical, and experimental study on laterally variable thickness (LVT) multi-cell tubes for crashworthiness
Publisher: Elsevier BV
Date: 11-2016
Quantitative/qualitative analysis of adhesive-dentin interface in the presence of 10-methacryloyloxydecyl dihydrogen phosphate
Publisher: Elsevier BV
Date: 04-2019
DOI: 10.1016/J.JMBBM.2018.12.038
Abstract: Dental adhesive provides effective retention of filling materials via adhesive-dentin hybridization. The use of co-monomers, such as 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP), is thought to be crucial for hybridization owing to their ionic-binding to calcium and co-polymerization in the polymerizable adhesives. Optimal hybridization partly depends on the mechanical properties of polymerized adhesives, which are likely to be proportional to the degree of conversion ratio. This study assessed the correlation between polymerization quality and mechanical properties at the adhesive-dentin interfaces in the presence or absence of 10-MDP. In situ Raman microspectroscopy and nanoindentation tests were used concurrently to quantify the degree of conversion ratio and dynamic mechanical properties across the adhesive-dentin interfaces. Despite the excellent diffusion and apparent higher degree of co-polymerization, 10-MDP reduced the elastic modulus of the interface. The higher viscoelastic properties of the adhesive are suggestive of poor polymerization, namely polymerization linearity related to the long carboxyl chain of 10-MDP. Such reduced mechanical integrity of hybridization could also be associated with the inhibition of nano-layering between 10-MDP and mineralized tissue in the presence of hydroxyethyl methacrylate (HEMA). This potential drawback of HEMA necessitates further qualitative/quantitative characterization of adhesive-dentin hybridization using a HEMA-free/low concentration experimental 10-MDP monomer, which theoretically possesses superior chemical bonding potential to the current HEMA-rich protocol.
Automated high quality isosurface modeling technique for iterative twophase problems
Publisher: Trans Tech Publications, Ltd.
Date: 05-2014
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMM.553.818
Abstract: While smooth isosurface and the subsequent body mesh construction is a well-developed modeling technique and widely used in medical imaging and engineering modeling, it is rarely performed in transient analysis and other iterative procedures due to relatively high computational cost. Voxelized modeling is often used as an alternative for simplicity at a cost of numerical accuracy. To overcome this problem, an isosurface modeling technique is developed in this paper to enable its seamless integration into iterative processes. This approach involves a rapid construction of closed isosurfaces using the Marching Cubes methods and a selective clean-up operation to smooth the surface mesh. This technique generates high quality isosurface meshes with clearly defined 3D domains and boundaries, which in turn provide a suitable foundation for the finite element analysis of two-phase problems. Its robustness, flexibility and suitability for applications in medical imaging and topology optimization are also demonstrated in this paper.
In-plane and out-of-plane bending responses of aluminum mortise-tenon joints in lightweight electric vehicle inspired by timber structures
Publisher: Elsevier BV
Date: 06-2018
Fibre reinforced composite dental bridge.
Publisher: Elsevier BV
Date: 09-2004
Multiobjective reliability-based optimization for crashworthy structures coupled with metal forming process
Publisher: Springer Science and Business Media LLC
Date: 07-10-2017
Fibre reinforced composite dental bridge. Part II: numerical investigation
Publisher: Elsevier BV
Date: 09-2004
Crashing analysis and multiobjective optimization for thin-walled structures with functionally graded thickness
Publisher: Elsevier BV
Date: 02-2014
In vitro study of the effect of cyclic strains on the dermal fibroblast (GM3384) morphology—Mapping of cell responses to strain field
Publisher: Elsevier BV
Date: 09-2012
DOI: 10.1016/J.MEDENGPHY.2011.09.024
Abstract: Cells can respond to mechanical forces and actively interact with mechanical stimulations in vitro. Understanding the effect of mechanical loading on cell morphology signifies a critical biomechanics issue in tissue engineering. In this study, human dermal fibroblasts (GM3384) underwent cyclic strain. This was done by culturing a monolayer of the cells onto a transparent membrane and applying a cyclic stress using a computer controlled bioreactor. The cells were mechanically stimulated at around 7% strain with 1 cycle per minute for 2 days. Finite element analysis (FEA) was then employed to characterize the strain field across the substrate membrane in the bioreactor. The results showed that strain distribution were non-uniform in the substrate membrane. The mapping of cell morphology with the strain field revealed that the cells exposed to the equibiaxial strain exhibited the classical spindle morphology while the cells subjected to uniaxial strain changed to a polygonal morphology. It is concluded that the nature of the strain has significant impact on the final cell morphology.
Time-dependent topology optimization of bone plates considering bone remodeling
Publisher: Elsevier BV
Date: 02-2020
Modeling for CFRP structures subjected to quasi-static crushing
Publisher: Elsevier BV
Date: 2018
Multi-fidelity optimization for sheet metal forming process
Publisher: Springer Science and Business Media LLC
Date: 30-12-2010
Parameterization of criss-cross configurations for multiobjective crashworthiness optimization
Publisher: Elsevier BV
Date: 05-2017
Biomechanical investigation into the role of the periodontal ligament in optimising orthodontic force: A finite element case study
Publisher: Elsevier BV
Date: 06-2016
DOI: 10.1016/J.ARCHORALBIO.2016.02.012
Abstract: This paper aimed to precisely locate centres of resistance (CRe) of maxillary teeth and investigate optimal orthodontic force by identifying the effective zones of orthodontic tooth movement (OTM) from hydrostatic stress thresholds in the periodontal ligament (PDL). We applied distally-directed tipping and bodily forces ranging from 0.075 N to 3 N (7.5 g to 300 g) onto human maxillary teeth. The hydrostatic stress was quantified from nonlinear finite element analysis (FEA) and compared with normal capillary and systolic blood pressure for driving the tissue remodelling. Two biomechanical stimuli featuring localised and volume-averaged hydrostatic stresses were introduced to describe OTM. Locations of CRe were determined through iterative FEA simulation. Accurate locations of CRes of teeth and ranges of optimal orthodontic forces were obtained. By comparing with clinical results in literature, the volume average of hydrostatic stress in PDL was proved to describe the process of OTM more indicatively. The optimal orthodontic forces obtained from the in-silico modelling study echoed with the clinical results in vivo. A universal moment to force (M/F) ratio is not recommended due to the variation in patients and loading points. Accurate computational determination of CRe location can be applied in practice to facilitate orthodontic treatment. Global measurement of hydrostatic pressure in the PDL better characterised OTM, implying that OTM occurs only when the majority of PDL volume is critically stressed. The FEA results provide new insights into relevant orthodontic biomechanics and help establish optimal orthodontic force for a specific patient.
Optimization of foam-filled bitubal structures for crashworthiness criteria
Publisher: Elsevier BV
Date: 06-2012
Topology optimisation for design and additive manufacturing of functionally graded lattice structures using derivative-aware machine learning algorithms
Publisher: Elsevier BV
Date: 10-2023
Comparing contact pressure induced by a conventional complete denture and an implant-retained overdenture
Publisher: Trans Tech Publications, Ltd.
Date: 05-2014
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMM.553.384
Abstract: Implant-retained overdenture has been widely applied as a solution to edentulous ageing however, a major concern for the denture wearers is bone resorption induced by the prosthetic interaction with soft tissue and bone. Early studies have revealed that the bone resorption is associated with the disturbance to the mucosa blood flow. This study aimed to investigate the contact pressure induced by an implant-retained overdenture, compared to a conventional complete denture without implants, which implies the potential bone resorption for clinical investigation. A three-dimensional finite element model of a full jaw, including mandible bone, mucosa, and denture, was created through a reverse engineering method based on CBCT images, in which the hyperelastic behaviour of mucosa was determined by curve-fitting to the clinical measurement, for a more realistic response. It is found that the location of the bone loss differed between the implant retained and non-implant complete dentures. With the implants, the denture displaced more at posterior ends towards the mucosa bearing area, leading to higher contact pressure accounted for more severe local bone loss.
Experimental and numerical study on honeycomb sandwich panels under bending and in-panel compression
Publisher: Elsevier BV
Date: 11-2017
Investigation of mucosa-induced residual ridge resorption under implant-retained overdentures and complete dentures in the mandible
Publisher: Quintessence Publishing
Date: 05-2015
DOI: 10.11607/JOMI.3844
Abstract: This study aimed to investigate and compare the residual ridge resorption (RRR) induced by an implant-retained overdenture (IRO) and associative biomechanics and by a conventional complete denture (CD) without implants. Cone beam computed tomography was used to quantify RRR in a three-dimensional (3D) manner before and after 1 year of treatment with either IROs or CDs. Twenty patients were treated with IROs, and nine patients were treated with CDs in the mandible. Their maximum bite forces were recorded. The same sets of high-resolution scan images were used to create patient-specific 3D finite element analysis models. The hydrostatic stresses, contact surface deformation, and strain energy absorption in soft tissue mucosa were correlated with the changes in RRR for patients with and without implants. With the IROs, contact surface deformation on the mucosa was two times greater than with CDs (0.32 ± 0.23 mm vs 0.16 ± 0.06 mm) and was in agreement with the amount of RRR measured, which was also two times higher for the IRO than the CD (-3.8% ± 4.5% vs -1.9% ± 0.4%). Taking into account the differences in bite forces with and without implants, which again were twice as high with IROs, the hydrostatic stress within the mucosa was found to correlate well to the RRR map measured over the 1-year interval of treatment. IROs resulted in at least twice the RRR as CDs. This could be caused by the higher hydrostatic stress and less effective energy absorption capabilities of the mucosa underneath the IRO. While implants associated with the IRO provide stronger bite force, they could potentially concentrate hydrostatic stress and cause greater RRR compared to a conventional CD.
Design of transversely-graded foam and wall thickness structures for crashworthiness criteria
Publisher: Elsevier BV
Date: 05-2016
A path-dependent level set topology optimization with fracture criterion
Publisher: Elsevier BV
Date: 06-2021
A two-stage multi-fidelity optimization procedure for honeycomb-type cellular materials
Publisher: Elsevier BV
Date: 09-2010
Crashworthiness study on functionally graded thin-walled structures
Publisher: Informa UK Limited
Date: 17-02-2015
Multi-objective and multi-case reliability-based design optimization for tailor rolled blank (TRB) structures
Publisher: Springer Science and Business Media LLC
Date: 17-10-2016
Mathematical modeling of degradation for bulk-erosive polymers: Applications in tissue engineering scaffolds and drug delivery systems
Publisher: Elsevier BV
Date: 03-2011
DOI: 10.1016/J.ACTBIO.2010.09.038
Abstract: The degradation of polymeric biomaterials, which are widely exploited in tissue engineering and drug delivery systems, has drawn significant attention in recent years. This paper aims to develop a mathematical model that combines stochastic hydrolysis and mass transport to simulate the polymeric degradation and erosion process. The hydrolysis reaction is modeled in a discrete fashion by a fundamental stochastic process and an additional autocatalytic effect induced by the local carboxylic acid concentration in terms of the continuous diffusion equation. Illustrative ex les of microparticles and tissue scaffolds demonstrate the applicability of the model. It is found that diffusive transport plays a critical role in determining the degradation pathway, whilst autocatalysis makes the degradation size dependent. The modeling results show good agreement with experimental data in the literature, in which the hydrolysis rate, polymer architecture and matrix size actually work together to determine the characteristics of the degradation and erosion processes of bulk-erosive polymer devices. The proposed degradation model exhibits great potential for the design optimization of drug carriers and tissue scaffolds.
Flexural performance and cost efficiency of carbon/basalt/glass hybrid FRP composite laminates
Publisher: Elsevier BV
Date: 09-2019
The all-ceramic, inlay supported fixed partial denture. Part 5. Extended finite element analysis validation
Publisher: Wiley
Date: 12-2013
DOI: 10.1111/ADJ.12107
Abstract: This study is the last in a series detailing an investigation into the all-ceramic, inlay supported fixed partial denture, the major concern of which has been the examination of the stress responses of the bridge via the use of finite element analysis (FEA) and its validation. The progression from a classic FEA to the current extended or enriched FEA (XFEA) will be described and the validation performed. XFEA modelling was compared and validated against the experimental model analysis (EMA) as described in a previous study. The two EMA load case fracture strengths of 160 N and 313 N compared favourably with the best two fracture predictions from the XFEA of 185 N and 213 N (maximum principal stress criterion) respectively, with the origin of fracture and overall trajectory and pattern of crack propagation agreeing very well. XFEA load prediction is within 15% of the EMA in the best case. The sensitivity of the bridges to loading position variations was accurately predicted by the XFEA, together with the change in fracture origin from the molar to premolar embrasures. With this, the authors believe that they have provided a convincing validation, both qualitatively and quantitatively, of an anatomically realistic dental bridge.
Variable fidelity design based surrogate and artificial bee colony algorithm for sheet metal forming process
Publisher: Elsevier BV
Date: 10-2012
On crashing behaviors of aluminium/CFRP tubes subjected to axial and oblique loading: An experimental study
Publisher: Elsevier BV
Date: 07-2018
Biofabrication: A Guide to Technology and Terminology
Publisher: Elsevier BV
Date: 04-2018
DOI: 10.1016/J.TIBTECH.2017.10.015
Abstract: Biofabrication holds the potential to generate constructs that more closely recapitulate the complexity and heterogeneity of tissues and organs than do currently available regenerative medicine therapies. Such constructs can be applied for tissue regeneration or as in vitro 3D models. Biofabrication is maturing and growing, and scientists with different backgrounds are joining this field, underscoring the need for unity regarding the use of terminology. We therefore believe that there is a compelling need to clarify the relationship between the different concepts, technologies, and descriptions of biofabrication that are often used interchangeably or inconsistently in the current literature. Our objective is to provide a guide to the terminology for different technologies in the field which may serve as a reference for the biofabrication community.
A stochastic process discretization method combing active learning Kriging model for efficient time-variant reliability analysis
Publisher: Elsevier BV
Date: 10-2021
Sensitivity analysis of bi-layered ceramic dental restorations
Publisher: Elsevier BV
Date: 02-2012
DOI: 10.1016/J.DENTAL.2011.11.012
Abstract: The reliability and longevity of ceramic prostheses have become a major concern. The existing studies have focused on some critical issues from clinical perspectives, but more researches are needed to address fundamental sciences and fabrication issues to ensure the longevity and durability of ceramic prostheses. The aim of this paper was to explore how "sensitive" the thermal and mechanical responses, in terms of changes in temperature and thermal residual stress of the bi-layered ceramic systems and crown models will be with respect to the perturbation of the design variables chosen (e.g. layer thickness and heat transfer coefficient) in a quantitative way. In this study, three bi-layered ceramic models with different geometries are considered: (i) a simple bi-layered plate, (ii) a simple bi-layer triangle, and (iii) an axisymmetric bi-layered crown. The layer thickness and convective heat transfer coefficient (or cooling rate) seem to be more sensitive for the porcelain fused on zirconia substrate models. The resultant sensitivities indicate a critical importance of the heat transfer coefficient and thickness ratio of core to veneer on the temperature distributions and residual stresses in each model. The findings provide a quantitative basis for assessing the effects of fabrication uncertainties and optimizing the design of ceramic prostheses.
Phase field fracture in elasto-plastic solids: Incorporating phenomenological failure criteria for ductile materials
Publisher: Elsevier BV
Date: 03-2022
Crushing analysis and design optimization for foam-filled aluminum/CFRP hybrid tube against transverse impact
Publisher: Elsevier BV
Date: 09-2020
On design of multi-functional microstructural materials
Publisher: Springer Science and Business Media LLC
Date: 06-07-2013
Parallelized multiobjective efficient global optimization algorithm and its applications
Publisher: Springer Science and Business Media LLC
Date: 03-01-2020
Effects of material on the deployment of coronary stents
Publisher: Trans Tech Publications, Ltd.
Date: 08-2010
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMR.123-125.315
Abstract: Coronary stents have been more and more widely used in clinic over the past decade. There have been a large number of stents made of different biocompatible materials available commercially in the market. It is however unclear which is more suitable to specific patients. This raises a major concern whether the choice of stents could be assessed before a delivery surgery. This paper aims to provide a computational approach for evaluating the effect of stent materials on biomechanical outcomes of the deployments of stents in different patient. It will review the typical biomaterials being used for coronary stents, seeking to qualitatively assess them for use as coronary stents. Non-linear explicit finite element (FE) procedure is carried out using the Palmaz-Schatz stent geometry to quantitatively predict the effect of mechanical properties of these biomaterials on stent and coronary artery behavior during stent deployment. A quantitative comparison is made for exploring the effect of different materials on the deployment of stents. The study is considered significant in understanding the role how stent materials affect biomechanical responses to the coronary stenting. It provides a new methodology to promote a patient-specific assessment before surgery.
Topology optimization of photonic band gap crystals
Publisher: Trans Tech Publications, Ltd.
Date: 05-2014
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMM.553.824
Abstract: This paper proposes a new topology optimization algorithm based on the bi-directional evolutionary structural optimization (BESO) method for the design of photonic band gap crystals. The photonic crystals are assumed to be periodically composed of two given dielectric materials. Based on the finite element analysis, the proposed BESO algorithm gradually re-distributes dielectric materials within the unit cell until the resulting photonic crystals possess a maximal band gap at the desirable frequency level. Numerical ex les for both transverse magnetic (TM) and transverse electric (TE) polarizations are presented, and the optimized photonic crystals exhibit novel patterns markedly different from traditional designs of photonic crystals.
A fixed-grid bidirectional evolutionary structural optimization method and its applications in tunnelling engineering
Publisher: Wiley
Date: 2008
DOI: 10.1002/NME.2145
A variational level set method for the topology optimization of steady-state Navier-Stokes flow
Publisher: Elsevier BV
Date: 12-2008
Bone’s responses to different designs of implant-supported fixed partial dentures
Publisher: Springer Science and Business Media LLC
Date: 11-09-2015
DOI: 10.1007/S10237-014-0612-6
Abstract: This paper explores the biomechanics and associated bone remodeling responses of two different abutment configurations, namely implant-implant-supported versus tooth-implant-supported fixed partial dentures. Two 3D finite element analysis models are created based upon computerized tomography data. The strain energy density induced by occlusal loading is used as a mechanical stimulus for driving the bone remodeling. To measure osseointegration and stability during healing, a resonance frequency analysis is conducted. At the second premolar peri-implant region, overloading resorption around the neck of implant is identified in both the models over the first 12 months. Stress-shielding around the edentulous region is also observed in both the models with a greater resorption rate found in the implant-implant case. The remodeling and resonance frequency analyses reveal that the tooth-implant scheme offers a higher degree of osseointegration. The remodeling procedure is expected to provide prosthodontists with a modeling tool to assess possible long-term clinical outcomes.
Multiobjective optimization for tapered circular tubes
Publisher: Elsevier BV
Date: 07-2011
Influence of blood vessel conductivity in cochlear implant stimulation using a finite element head model
Publisher: IEEE
Date: 07-2013
A New Homogenization Formulation for Multifunctional Composites
Publisher: World Scientific Pub Co Pte Lt
Date: 03-2016
DOI: 10.1142/S0219876216400028
Abstract: Periodic microstructural composites have gained considerable attention in material science and engineering attributable to their excellent flexibility in tailoring various desirable physical properties. Conventionally, the finite element technique has been widely used in implementing the homogenization. However, the standard finite element method (FEM) leads to an overly stiff model which sometimes gives unsatisfactory accuracy especially using triangular elements in 2D or tetrahedral elements in 3D with coarse mesh. In this paper, different forms of smoothed finite element method (SFEM) are presented to develop new asymptotic homogenization techniques for analyzing various effective physical properties of periodic microstructural composite materials. A range of multifunctional material ex les, including elastic modulus with multiphase composites, conductivity of thermal and electrical composites, and diffusivity ermeability of 3D tissue scaffold, has exemplified herein to demonstrate that SFEM is able to provide more accurate results using the same set of mesh compared with the standard FEM. In addition, the computational efficiency of SFEM is also higher than that of the standard FEM counterpart.
On fatigue failure prediction of prosthetic devices through XFEM analysis
Publisher: Elsevier BV
Date: 06-2021
Multi-objective topology optimization of a vehicle door using multiple material tailor-welded blank (TWB) technology
Publisher: Elsevier BV
Date: 10-2018
Low-velocity impact behaviour of sandwich panels with homogeneous and stepwise graded foam cores
Publisher: Elsevier BV
Date: 12-2018
On fracture characteristics of adhesive joints with dissimilar materials – An experimental study using digital image correlation (DIC) technique
Publisher: Elsevier BV
Date: 10-2018
Evolutionary topology optimization for temperature reduction of heat conducting fields
Publisher: Elsevier BV
Date: 11-2004
Multiobjective optimization of cartilage stress for non-invasive, patient-specific recommendations of high tibial osteotomy correction angle – a novel method to investigate alignment correction
Publisher: Elsevier BV
Date: 04-2017
DOI: 10.1016/J.MEDENGPHY.2016.11.013
Abstract: Medial opening wedge high tibial osteotomy (MOWHTO) is a surgical procedure to treat knee osteoarthritis associated with varus deformity. However, the ideal final alignment of the Hip-Knee-Ankle (HKA) angle in the frontal plane, that maximizes procedural success and post-operative knee function, remains controversial. Therefore, the purpose of this study was to introduce a subject-specific modeling procedure in determining the biomechanical effects of MOWHTO alignment on tibiofemoral cartilage stress distribution. A 3D finite element knee model derived from magnetic resonance imaging of a healthy participant was manipulated in-silico to simulate a range of final HKA angles (i.e. 0.2°, 2.7°, 3.9° and 6.6° valgus). Loading and boundary conditions were assigned based on subject-specific kinematic and kinetic data from gait analysis. Multiobjective optimization was used to identify the final alignment that balanced compressive and shear forces between medial and lateral knee compartments. Peak stresses decreased in the medial and increased in the lateral compartment as the HKA was shifted into valgus, with balanced loading occurring at angles of 4.3° and 2.9° valgus for the femoral and tibial cartilage respectively. The concept introduced here provides a platform for non-invasive, patient-specific preoperative planning of the osteotomy for medial compartment knee osteoarthritis.
On the shape transformation of cone scales
Publisher: Royal Society of Chemistry (RSC)
Date: 2016
DOI: 10.1039/C6SM01805J
Abstract: The shape-morphing behaviours of some biological systems have drawn considerable interest over many years. This paper ulges that the opening and closing mechanism of pine cones is attributed to the self-bending of their scales, which undergo three states of humidity-driven deformation in terms of Föppl-von Kármán plate theory. Both numerical simulation and experimental measurement support the theoretical analysis, showing that the longitudinal principal curvature and the transverse principal curvature bifurcate at a critical humidity level according to the thickness and shape of scales. These findings help us understand the shape transformation of bilayer or multi-layer natural structures and gain insights into the design of transformable devices/materials with great potential in numerous applications.
Multiobjective discrete optimization using the TOPSIS and entropy method for protection of pedestrian lower extremity
Publisher: Elsevier BV
Date: 07-2020
Multiscale Bone Remodeling Prediction for Fully Porous-Coated (FPC) Dental Implant Supported Prosthesis
Publisher: Trans Tech Publications, Ltd.
Date: 08-2009
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMR.79-82.2167
Abstract: This paper aims at providing a preliminary understanding in biomechanics with respect to the effect of FPC dental implants on bone remodelling. 2D multi-scale finite element models are created for a typical dental implantation setting. Under a certain mastication force ( N), a global response from a macro-scale model (without considering coated surface morphology details) is first obtained and then it is transferred to the micro-scale models (with coated surface morphology details and various particle sizes) for micro-scale analysis. A strain energy density (SED) obtained from 2D micro-scale Finite Element Analysis (FEA) is used as a mechanical stimulus to determine the bone remodeling in term of the change in apparent bone densities for cancellous and cortical bones. The change in bone densities is examined as a result of bone remodelling activities over a period of 48 months.
Dynamic crashing behavior of new extrudable multi-cell tubes with a functionally graded thickness
Publisher: Elsevier BV
Date: 11-2015
A microstructure diagram for known bounds in conductivity
Publisher: Springer Science and Business Media LLC
Date: 03-2008
Abstract: Two important analytical means—theoretical bounds and homogenization techniques—have gained increasing attention and led to substantial progress in material research. Nevertheless, there is a lack of relating material microstructures to an entire theoretical bound and exploring the possibility of generating multiple microstructures for each property value. This paper aims to provide a microstructure diagram in relation to “bound B” constructed by translation and Weiner bounds. The inverse homogenization technique is used to seek for the optimal phase distribution within a base cell model to make the effective conductivity approach the “bound B” in two- or three-phase material cases. The design shows that the “bound B” is exactly attainable for two-phase composites even with single-length-scale microstructures. Although the multiphase translations bounds are well known to be asymptotically attainable on some parts, they still appear too roomy to be attained by single-length-scale composites. Our results showed a certain improvement in the attainability of single-length-scale structural composites when compared with new bounds established by [V. Nesi: Proc. R. Soc. Edinburgh Sect. A 125, 1219 (1995)], [V. Cherkaev: Variational Methods for Structural Optimization (Springer Verlag, New York, 2000)], and (N. Albin et al.: Proc. R. Soc. London Ser. A 463, 2031 (2007)]. Applicability of the translation bounds to the composites with high-contrast conductivities of phase compositions is also studied in this paper. Finally, we explore the multiple solutions to the optimal microstructures and categorize them into three classes in line with their topological resemblance, namely, spatially identical, unidirectionally identical, and bidirectionally different solutions.
A strength-based multiple cutout optimization in composite plates using fixed grid finite element method
Publisher: Elsevier BV
Date: 06-2006
On hierarchical honeycombs under out-of-plane crushing
Publisher: Elsevier BV
Date: 03-2018
Crashworthiness design of functionally graded structures with variable diameters
Publisher: Informa UK Limited
Date: 24-10-2016
Mechanical characterization and numerical modeling on the yield and fracture behaviors of polymethacrylimide (PMI) foam materials
Publisher: Elsevier BV
Date: 03-2022
Subject specific finite element modeling of periprosthetic femoral fracture using element deactivation to simulate bone failure
Publisher: Elsevier BV
Date: 06-2015
DOI: 10.1016/J.MEDENGPHY.2015.03.012
Abstract: Subject-specific finite element (FE) modeling methodology could predict peri-prosthetic femoral fracture (PFF) for cementless hip arthoplasty in the early postoperative period. This study develops methodology for subject-specific finite element modeling by using the element deactivation technique to simulate bone failure and validate with experimental testing, thereby predicting peri-prosthetic femoral fracture in the early postoperative period. Material assignments for biphasic and triphasic models were undertaken. Failure modeling with the element deactivation feature available in ABAQUS 6.9 was used to simulate a crack initiation and propagation in the bony tissue based upon a threshold of fracture strain. The crack mode for the biphasic models was very similar to the experimental testing crack mode, with a similar shape and path of the crack. The fracture load is sensitive to the friction coefficient at the implant-bony interface. The development of a novel technique to simulate bone failure by element deactivation of subject-specific finite element models could aid prediction of fracture load in addition to fracture risk characterization for PFF.
Experimental investigation into stamping of woven CF/PP laminates: Influences of molding temperature on thermal, mesoscopic and macroscopic properties
Publisher: Elsevier BV
Date: 05-2021
Multi-material topology optimization for thermal buckling criteria
Publisher: Elsevier BV
Date: 04-2019
A continuum sensitivity method for the design of multi-stage metal forming processes
Publisher: Elsevier BV
Date: 02-2003
Modeling the effects of electrode recessing on electrochemical safety in cochlear implant electrodes
Publisher: IEEE
Date: 04-2015
Three dimensional quantification of mandibular bone remodeling using standard tessellation language registration based superimposition
Publisher: Wiley
Date: 02-08-2013
DOI: 10.1111/J.1600-0501.2012.02566.X
Abstract: The aim of this study was to evaluate a new method to quantify longitudinal mandibular bone remodeling three-dimensionally by superimposition of cone beam computed tomography images. This method is used to quantify the treatment effects of implant-retained overdentures in 20 patients aged 52-79 at recruitment after 1 and 2 years post treatment. Three dimensional models of pre- and post-treatment were reconstructed for each patient and superimposed using Standard Tessellation Language registration method and segmentation. Color maps of the differences generated by superimposition allow detailed examination and quantification of the progressive dimensional changes of bone in a three-dimensional manner and enable the visualization of the apical displacement and thinning of the cortical layer of bone underneath the denture base. Most of the remodeling changes took place during the first year with a mean decrease in volume of 3.7% (SD = 4.4% range = +3.7% to -15.9%, median = -3.7%). This remodeling pattern continued during the second year, but at a reduced rate of 2.5% per year (SD = 4.2% range = +2.1% to -11.3%, median = -3.9%). Standard Tessellation Language registration based superimposition of cone beam computed tomography images may be considered an objective and reproducible method to three-dimensionally quantify mandibular bone remodeling.
A two-stage multi-objective optimisation of vehicle crashworthiness under frontal impact
Publisher: Informa UK Limited
Date: 07-05-2008
On energy absorption of functionally graded tubes under transverse loading
Publisher: Elsevier BV
Date: 09-2016
Modelling of fracture behaviour in biomaterials
Publisher: Elsevier BV
Date: 03-2007
DOI: 10.1016/J.BIOMATERIALS.2006.10.035
Abstract: One of the most frequent causes of degradation and failure of quasi-brittle biomaterials is fracture. Mechanical breakdown, even when not catastrophic, is of particular importance in the area of biomaterials, as there are many clinical situations where it opens the path for biologically mediated failures. Over the past few decades the materials/biomaterials community has developed a number of numerical models, but only with limited incorporation of brittle failure phenomena. This article investigates the ability of a non-linear elastic fracture mechanics (NLEFM) model to reliably predict failure of biomaterials with a specific focus on the clinical settings of restorative dentistry. The approach enables one to predict fracture initiation and propagation in a complex biomechanical status based on the intrinsic material properties of the components. In this paper, we consider five ex les illustrating the versatility of the present approach, which range from the failure of natural biomaterials, namely dentine and enamel, to a restored tooth, a three unit all ceramic bridge structure and contact-induced damage in the restorative layered materials systems. It is anticipated that this approach will have ramifications not only to model fracture events but also for the design and optimisation of the mechanical properties of biomaterials for specific clinically determined requirements.
Numerical simulation of crack formation in all ceramic dental bridge
Publisher: Trans Tech Publications Ltd.
Date: 15-06-2006
Experimental and numerical studies on indentation and perforation characteristics of honeycomb sandwich panels
Publisher: Elsevier BV
Date: 2018
Design of fiber metamaterials with negative refractive index in the infrared
Publisher: The Optical Society
Date: 06-07-2015
DOI: 10.1364/OE.23.018236
Modelling of stress distribution and fracture in dental occlusal fissures
Publisher: Springer Science and Business Media LLC
Date: 18-03-2019
DOI: 10.1038/S41598-019-41304-Z
Abstract: The aim of this study was to investigate the fracture behaviour of fissural dental enamel under simulated occlusal load in relation to various interacting factors including fissure morphology, cuspal angle and the underlying material properties of enamel. Extended finite element method (XFEM) was adopted here to analyse the fracture load and crack length in tooth models with different cusp angles (ranging from 50° to 70° in 2.5° intervals), fissural morphologies (namely U shape, V shape, IK shape, I shape and Inverted-Y shape) and enamel material properties (constant versus graded). The analysis results showed that fissures with larger curved morphology, such as U shape and IK shape, exhibit higher resistance to fracture under simulated occlusal load irrespective of cusp angle and enamel properties. Increased cusp angle (i.e. lower cusp steepness), also significantly enhanced the fracture resistance of fissural enamel, particularly for the IK and Inverted-Y shape fissures. Overall, the outcomes of this study explain how the interplay of compositional and structural features of enamel in the fissural area contribute to the resistance of the human tooth against masticatory forces. These findings may provide significant indicators for clinicians and technicians in designing/fabricating extra-coronal dental restorations and correcting the cuspal inclinations and contacts during clinical occlusal adjustment.
On functionally-graded crashworthy shape of conical structures for multiple load cases
Publisher: Springer Science and Business Media LLC
Date: 06-2017
Crashworthiness optimization with uncertainty from surrogate model and numerical error
Publisher: Elsevier BV
Date: 08-2018
A novel specimen design to establish the forming limit diagram (FLD) for GFRP through stamping test
Publisher: Elsevier BV
Date: 03-2020
Characterization of initial and subsequent yield behaviors of closed-cell aluminum foams under multiaxial loadings
Publisher: Elsevier BV
Date: 12-2020
Finite element based bone remodeling and resonance frequency analysis for osseointegration assessment of dental implants
Publisher: Elsevier BV
Date: 08-2011
Failure mechanisms in carbon fiber reinforced plastics (CFRP) / aluminum (Al) adhesive bonds subjected to low-velocity transverse pre-impact following by axial post-tension
Publisher: Elsevier BV
Date: 09-2019
Microstructural design of connective base cells for functionally graded materials
Publisher: Elsevier BV
Date: 09-2008
Buckling-Induced Assembly of Three-Dimensional Tunable Metamaterials
Publisher: Wiley
Date: 15-02-2018
Creating biomaterials inspired by the microstructure of cuttlebone
Publisher: Trans Tech Publications, Ltd.
Date: 06-2010
DOI: 10.4028/WWW.SCIENTIFIC.NET/MSF.654-656.2229
Abstract: The microstructure of cuttlebone is investigated using Scanning Electron Microscopy (SEM). A graded aspect ratio of the base cells between layers is evident in some s les. A method for designing graded biomaterials mimicking this cuttlebone microstructure is developed. Simplified 3D biomaterial s les are created using CAD software. These biomaterials are fabricated using a stereolithographic apparatus (SLA). The homogenisation technique is used to evaluate the mechanical properties of the original cuttlebone s le and the fabricated biomaterial s le. Good agreement is found between the Young’s moduli of corresponding layers. However, it is inconclusive whether the Young’s moduli have a proportional relationship to the aspect ratio of the base cell at this stage of the study.
Crushing analysis of foam-filled single and bitubal polygonal thin-walled tubes
Publisher: Elsevier BV
Date: 10-2014
A New NURBS Tool Path Generation Algorithm for Precise Sculptured Surface Machining
Publisher: Trans Tech Publications, Ltd.
Date: 03-2010
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMR.97-101.2477
Abstract: This paper proposes a new approach to tool path generation in precision machining of parts with sculptured surface. It aims to develop an effective NURBS fitting algorithm suitable for machining sophisticated parts requiring smooth profile on sculptured surface. In order to generate NURBS tool path with fewer control points, a dual-loop fitting technique is proposed in this paper. A general sculptured surface model is used to test the effectiveness of this method. It is shown that the proposed algorithm proved to be robust and effective in generating precise NURBS tool path. This makes the proposed algorithm suitable to convert conventional CNC tool path to more precise NURBS tool path. This approach may be of potential to be widely implemented in the manufacturing industry.
Experimental investigation on high strength steel (HSS) tailor-welded blanks (TWBs)
Publisher: Elsevier BV
Date: 04-2014
On failure mechanisms in CFRP/Al adhesive joints after hygrothermal aging degradation following by mechanical tests
Publisher: Elsevier BV
Date: 2021
Numerical investigation into impact responses of an offshore wind turbine jacket foundation subjected to ship collision
Publisher: Elsevier BV
Date: 03-2022
Finite element analysis suggests functional bone strain accounts for continuous post-eruptive emergence of teeth
Publisher: Elsevier BV
Date: 08-2012
DOI: 10.1016/J.ARCHORALBIO.2012.05.001
Abstract: To explore the possible role of functional stress in driving continuous post-eruptive emergence of teeth. A two dimensional finite element analysis model was established with a single mandibular premolar subjected to sagittal bending. Equivalent strain was charted for the inner and outer surfaces of the lamina dura, because bone deposition and resorption of this structure is confined to surface osteoblasts and osteoclasts. Bone disuse resorption was assumed to take place at equivalent strain values below 0.0008, while deposition was above 0.002. Strain in the periodontal ligament and principal stress throughout the model were also characterized. Strain analysis indicated bone maintenance for the lamina dura throughout most of the root length, but in both the apical and upper root regions, resorption was predicted for the outer surface, and bone deposition was predicted for the inner surface of the lamina dura. Strain in the periodontal ligament varied little with the exception of a marked increase close to the crown. Principal stress analysis revealed compression of the lower model border, with areas of increasing tension towards the upper model border. Strain from functional forces may continuously drive post-eruptive emergence of teeth through bony remodelling of the lamina dura, lifting teeth by both raising the apical lamina dura, and narrowing the upper root space to accommodate tapering root form. Such strain-driven bone turnover may contribute to pre-eruptive movement of teeth.
Biomechanical analysis of bone remodeling following mandibular reconstruction using fibula free flap
Publisher: Elsevier BV
Date: 06-2018
DOI: 10.1016/J.MEDENGPHY.2018.03.008
Abstract: Whilst the newly established biomechanical conditions following mandibular reconstruction using fibula free flap can be a critical determinant for achieving favorable bone union, little has been known about their association in a time-dependent fashion. This study evaluated the bone healing/remodeling activity in reconstructed mandible and its influence on jaw biomechanics using CT data, and further quantified their correlation with mechanobiological responses through an in-silico approach. A 66-year-old male patient received mandibular reconstruction was studied. Post-operative CT scans were taken at 0, 4, 16 and 28 months. Longitudinal change of bone morphologies and mineral densities were measured at three bone union interfaces (two between the fibula and mandibular bones and one between the osteotomized fibulas) to investigate bone healing/remodeling events. Three-dimensional finite element models were created to quantify mechanobiological responses in the bone at these different time points. Bone mineral density increased rapidly along the bone interfaces over the first four months. Cortical bridging formed at the osteotomized interface earlier than the other two interfaces with larger shape discrepancy between fibula and mandibular bones. Bone morphology significantly affected mechanobiological responses in the osteotomized region (R
Time-dependent reliability analysis through response surface method
Publisher: ASME International
Date: 24-02-2017
DOI: 10.1115/1.4035860
Abstract: In time-dependent reliability analysis, the first-passage method has been extensively used to evaluate structural reliability under time-variant service circumstances. To avoid computing the outcrossing rate in this method, surrogate modeling may provide an effective alternative for calculating the time-dependent reliability indices in structural analysis. A novel approach, namely time-dependent reliability analysis with response surface (TRARS), is thus introduced in this paper to estimate the time-dependent reliability for nondeterministic structures under stochastic loads. A Gaussian stochastic process is generated by using the expansion optimal linear estimation (EOLE) method which has proven to be more accurate and efficient than some series expansion discretization techniques. The random variables and maximum responses of uncertain structures are treated as the input and output parameters, respectively. Through introducing the response surface (RS) model, a novel iterative procedure is proposed in this study. A Bucher strategy is adopted to generate the initial s le points, and a gradient projection technique is used to generate new s ling points for updating the RS model in each iteration. The time-dependent reliability indices and probabilities of failure are thus obtained efficiently using the first-order reliability method (FORM) over a certain design lifetime. In this study, four demonstrative ex les are provided for illustrating the accuracy and efficiency of the proposed method.
A Kirigami Approach to Forming a Synthetic Buckliball
Publisher: Springer Science and Business Media LLC
Date: 09-09-2016
DOI: 10.1038/SREP33016
Abstract: The shape transformation of some biological systems inspires scientists to create sophisticated structures at the nano- and macro- scales. However, to be useful in engineering, the mechanics of governing such a spontaneous, parallel and large deformation must be well understood. In this study, a kirigami approach is used to fold a bilayer planar sheet featuring a specific pattern into a buckliball under a certain thermal stimulus. Importantly, this prescribed spherical object can retract into a much smaller sphere due to constructive buckling caused by radially inward displacement. By minimizing the potential strain energy, we obtain a critical temperature, below which the patterned sheet exhibits identical principal curvatures everywhere in the self-folding procedure and above which buckling occurs. The applicability of the theoretical analysis to the self-folding of sheets with a ersity of patterns is verified by the finite element method.
Optimization design of corrugated beam guardrail based on RBF-MQ surrogate model and collision safety consideration
Publisher: Elsevier BV
Date: 12-2014
Residual stresses in fabrication of core-veneered ceramic prostheses
Publisher: Trans Tech Publications, Ltd.
Date: 03-2010
DOI: 10.4028/WWW.SCIENTIFIC.NET/AMR.97-101.2241
Abstract: Fabrication of multilayered ceramics signifies an important topic in many advanced applications aerospace and prosthetic dentistry. This paper presents a numerical approach to characterising the transient thermal responses and corresponding thermal residual stresses that are developed in the bi-layered dental ceramic crowns model under a controlled cooling rate from a temperature around its glass transition temperature (typically 550°C) to room temperature (25°C). Finite element method (FEM) is adopted to model the residual stresses in normal or rapid cooling fabrication process. The demonstrative ex les take into account the effect of thickness in core veneered all-ceramic restorative prosthesis (specific porcelain bonded to an alumina or zirconia core layer), cooling rates and mismatches in temperature-dependent material properties such as thermal expansion coefficients, specific heat and Young’s modulus. The model of transient ceramic fabrication processing showed significant potential to development of optimal prosthetic devices.
Discrete robust optimization algorithm based on Taguchi method for structural crashworthiness design
Publisher: Elsevier BV
Date: 06-2015
Static and dynamic crushing responses of CFRP sandwich panels filled with different reinforced materials
Publisher: Elsevier BV
Date: 03-2017
Failure analysis for resistance spot welding in lap-shear specimens
Publisher: Elsevier BV
Date: 2014
Improved mode Ⅰ interlaminar fracture toughness of random polypropylene composite laminate via multiscale reinforcing formed by introducing functional nanofibrillated cellulose
Publisher: Elsevier BV
Date: 12-2020
Double-negative metamaterial from conducting spheres with a high-permittivity shell
Publisher: The Optical Society
Date: 31-07-2014
DOI: 10.1364/OL.39.004587
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