ORCID Profile
0000-0001-8866-9486
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Quantum Optics And Lasers | Optical Physics | Optics And Opto-Electronic Physics | Atomic And Molecular Physics | Atomic, Molecular, Nuclear, Particle and Plasma Physics | Quantum Physics | Macromolecular and Materials Chemistry | Classical Physics | Optical And Photonic Systems | Chemical Sciences Not Elsewhere Classified | Earth Sciences Not Elsewhere Classified | Transport Properties and Non-Equilibrium Processes | Optical Physics not elsewhere classified | Biophysics | Neurosciences | Cellular Nervous System | Theoretical Physics | Quantum Optics | Photonics, Optoelectronics and Optical Communications | Nonlinear Optics and Spectroscopy | Thermodynamics and Statistical Physics | Classical and Physical Optics | Physical Sciences Not Elsewhere Classified
Physical sciences | Scientific instrumentation | Telecommunications | Higher education | Expanding Knowledge in the Physical Sciences | Data, image and text equipment | Industrial instrumentation | Medical instrumentation | Network switching equipment | Chemical sciences | Expanding Knowledge in the Medical and Health Sciences | Expanding Knowledge in the Biological Sciences |
Publisher: American Association of Physics Teachers (AAPT)
Date: 11-2008
DOI: 10.1119/1.2969722
Abstract: Quantum noise is a key feature of laser beams. It is both a limiting effect in contemporary optical measurements and a manifestation of the quantum nature of light. Its properties distinguish it from classical noise. We demonstrate a simple, reliable, and portable apparatus using low cost commercial lasers and electronics that provides evidence of these properties.
Publisher: Frontiers Media SA
Date: 16-02-2202
Abstract: Dendritic spikes facilitate neuronal computation and they have been reported to occur in various regions of the dendritic tree of cortical neurons. Spikes that occur only on a select few branches are particularly difficult to analyze especially in complex and intertwined dendritic arborizations where highly localized application of pharmacological blocking agents is not feasible. Here, we present a technique based on highly targeted dendrotomy to tease out and study dendritic spikes that occur in oblique branches of cortical layer five pyramidal neurons. We first analyze the effect of cutting dendrites in silico and then confirmed in vitro using an ultrafast laser scalpel. A dendritic spike evoked in an oblique branch manifests at the soma as an increase in the afterdepolarization (ADP). The spikes are branch-specific since not all but only a few oblique dendrites are observed to evoke spikes. Both our model and experiments show that cutting certain oblique branches, where dendritic spikes are evoked, curtailed the increase in the ADP. On the other hand, cutting neighboring oblique branches that do not evoke spikes maintained the ADP. Our results show that highly targeted dendrotomy can facilitate causal analysis of how branch-specific dendritic spikes influence neuronal output.
Publisher: American Physical Society (APS)
Date: 30-11-2006
Publisher: IOP Publishing
Date: 28-07-2004
Publisher: IEEE
Date: 06-2013
Publisher: American Physical Society (APS)
Date: 10-03-2003
Publisher: IOP Publishing
Date: 21-06-2000
Publisher: SPIE
Date: 09-06-2010
DOI: 10.1117/12.859123
Publisher: SPIE
Date: 19-08-2010
DOI: 10.1117/12.862388
Publisher: The Optical Society
Date: 2007
DOI: 10.1364/OE.15.005310
Abstract: We experimentally demonstrate the generation of optical squeezing at multiple longitudinal modes and transverse Hermite-Gauss modes of an optical parametric lifier. We present measurements of approximately 3 dB squeezing at baseband, 1.7 GHz, 3.4 GHz and 5.1 GHz which correspond to the first, second and third resonances of the lifier. We show that both the magnitude and the bandwidth of the squeezing at the higher longitudinal modes is greater than can be observed at baseband. The squeezing observed is the highest frequency squeezing reported to date.
Publisher: IOP Publishing
Date: 08-2015
Publisher: American Physical Society (APS)
Date: 10-12-2009
Publisher: American Physical Society (APS)
Date: 14-03-2005
Publisher: IOP Publishing
Date: 25-11-2010
Publisher: Wiley
Date: 16-02-2012
Abstract: We demonstrate simultaneous multi-site two-photon photolysis of caged neurotransmitters with close to diffraction-limited resolution in all three dimensions (3D). We use holographic projection of multiple focal spots, which allows full control over the 3D positions of uncaging sites with a high degree of localized excitation. Our system incorporates a two-photon imaging setup to visualize the 3D morphology of the neurons in order to accurately determine the photostimulation sites. We show its application to studies of synaptic integration by performing simultaneous and controlled glutamate delivery at multiple locations on dendritic trees.
Publisher: Informa UK Limited
Date: 11-1990
Publisher: IOP Publishing
Date: 20-12-2006
Publisher: IEEE
Date: 08-2011
Publisher: IEEE
Date: 2005
Publisher: IOP Publishing
Date: 28-11-2018
Publisher: OSA
Date: 2012
Publisher: IOP Publishing
Date: 08-2000
Publisher: The Optical Society
Date: 29-10-2010
Publisher: American Physical Society (APS)
Date: 1994
Publisher: IEEE
Date: 06-2007
Publisher: Springer New York
Date: 2007
Publisher: American Physical Society (APS)
Date: 12-1986
Publisher: Springer Science and Business Media LLC
Date: 11-2003
Publisher: AIP Publishing
Date: 31-08-2009
DOI: 10.1063/1.3216581
Abstract: We demonstrate dynamic and arbitrary multisite two-photon excitation in three dimensions using the holographic projection method. Rapid response (fourth dimension) is achieved through high-speed noniterative calculation of the hologram using a video graphics accelerator board. We verify that the projected asymmetric spot configurations have sufficient spatiotemporal photon density for localized two-photon excitation. This system is a significant advance and can be applied to time-resolved photolysis of caged compounds in biological cells and complex neuronal networks, nonlinear microfabrication and volume holographic optical storage.
Publisher: Wiley
Date: 08-11-2017
DOI: 10.1002/AGR.21524
Publisher: Elsevier BV
Date: 02-1986
Publisher: The Optical Society
Date: 29-11-2016
DOI: 10.1364/BOE.7.005325
Publisher: American Physical Society (APS)
Date: 04-02-2014
Publisher: Springer Science and Business Media LLC
Date: 26-10-2005
Publisher: IOP Publishing
Date: 1992
Publisher: The Optical Society
Date: 27-04-2007
DOI: 10.1364/OE.15.005815
Abstract: Second harmonic generation (SHG) can be used as a technique for controlling the spatial mode structure of optical beams. We demonstrate experimentally the generation of higher-order spatial modes, and the possibility to use nonlinear phase matching as a predictable and robust technique for the conversion of transverse electric modes of the second harmonic output. The details of this effect are well described by our wave propagation models, which include mode dependent phase shifts. This is, to our knowledge, the first detailed study of spatial mode conversion in SHG. We discuss potential applications of this effect.
Publisher: Optica Publishing Group
Date: 10-2009
DOI: 10.1364/OE.17.018693
Publisher: The Optical Society
Date: 15-05-2006
DOI: 10.1364/OL.31.001537
Abstract: We consider the problem of measurement of optical transverse profile parameters and their conjugate variable. Using multimode analysis, we introduce the concept of detection noise modes. For Gaussian beams, displacement and tilt are a pair of transverse-profile conjugate variables. We experimentally demonstrate the optimal encoding and detection of these variables with a spatial homodyning scheme. Using higher-order spatial mode squeezing, we show the sub-shot-noise measurements for the displacement and tilt of a Gaussian beam.
Publisher: Springer Science and Business Media LLC
Date: 06-1988
DOI: 10.1007/BF01384505
Publisher: Elsevier BV
Date: 10-2002
Publisher: Springer Science and Business Media LLC
Date: 02-2021
DOI: 10.1007/S12551-021-00780-2
Abstract: The challenge to understand the complex neuronal circuit functions in the mammalian brain has brought about a revolution in light-based neurotechnologies and optogenetic tools. However, while recent seminal works have shown excellent insights on the processing of basic functions such as sensory perception, memory, and navigation, understanding more complex brain functions is still unattainable with current technologies. We are just scratching the surface, both literally and figuratively. Yet, the path towards fully understanding the brain is not totally uncertain. Recent rapid technological advancements have allowed us to analyze the processing of signals within dendritic arborizations of single neurons and within neuronal circuits. Understanding the circuit dynamics in the brain requires a good appreciation of the spatial and temporal properties of neuronal activity. Here, we assess the spatio-temporal parameters of neuronal responses and match them with suitable light-based neurotechnologies as well as photochemical and optogenetic tools. We focus on the spatial range that includes dendrites and certain brain regions (e.g., cortex and hippoc us) that constitute neuronal circuits. We also review some temporal characteristics of some proteins and ion channels responsible for certain neuronal functions. With the aid of the photochemical and optogenetic markers, we can use light to visualize the circuit dynamics of a functioning brain. The challenge to understand how the brain works continue to excite scientists as research questions begin to link macroscopic and microscopic units of brain circuits.
Publisher: Informa UK Limited
Date: 11-2005
Publisher: American Physical Society (APS)
Date: 03-11-2006
Publisher: American Physical Society (APS)
Date: 28-01-2003
Publisher: IEEE
Date: 2003
Publisher: The Optical Society
Date: 20-05-2006
DOI: 10.1364/AO.45.003415
Abstract: We present the first detector that is capable of recording high-bandwidth atom number density measurements of a Bose-Einstein condensate, with a readout of the data in real time. It is based on a shot-noise-limited unbalanced Mach-Zehnder interferometer designed for a minimally destructive measurement of the atom column density of a Bose-Einstein condensate. The shot-noise limit is reached by phase modulating the laser in one arm and phase locking the interferometer with a second-color laser. The detector is characterized, and its sensitivity for a fractional change in the column density of a Bose-Einstein condensate is calculated. With this detection system it may be possible to implement feedback to stabilize a Bose-Einstein condensate or an atom laser.
Publisher: American Physical Society (APS)
Date: 04-1986
Publisher: IOP Publishing
Date: 08-1999
Publisher: Springer Science and Business Media LLC
Date: 21-06-2009
Publisher: IEEE
Date: 06-2007
Publisher: Springer Science and Business Media LLC
Date: 06-08-2020
DOI: 10.1038/S41467-020-17305-2
Abstract: How the genome activates or silences transcriptional programmes governs organ formation. Little is known in human embryos undermining our ability to benchmark the fidelity of stem cell differentiation or cell programming, or interpret the pathogenicity of noncoding variation. Here, we study histone modifications across thirteen tissues during human organogenesis. We integrate the data with transcription to build an overview of how the human genome differentially regulates alternative organ fates including by repression. Promoters from nearly 20,000 genes partition into discrete states. Key developmental gene sets are actively repressed outside of the appropriate organ without obvious bivalency. Candidate enhancers, functional in zebrafish, allow imputation of tissue-specific and shared patterns of transcription factor binding. Overlaying more than 700 noncoding mutations from patients with developmental disorders allows correlation to unanticipated target genes. Taken together, the data provide a comprehensive genomic framework for investigating normal and abnormal human development.
Publisher: The Optical Society
Date: 17-09-2015
DOI: 10.1364/BOE.6.004027
Publisher: IOP Publishing
Date: 05-04-2002
Publisher: IOP Publishing
Date: 08-1995
Publisher: IEEE
Date: 06-2007
Publisher: OSA
Date: 2011
Publisher: IOP Publishing
Date: 28-06-1980
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 10-2006
Publisher: Oxford University Press (OUP)
Date: 2017
DOI: 10.1039/C7MT00201G
Abstract: Organ and tissue-level studies demonstrate selenium binding to arsenic in vivo in mammals, facilitating excretion.
Publisher: Springer Science and Business Media LLC
Date: 09-1986
DOI: 10.1007/BF01436680
Publisher: Elsevier BV
Date: 10-2004
Publisher: Informa UK Limited
Date: 03-1997
Publisher: Elsevier BV
Date: 11-1989
Publisher: IOP Publishing
Date: 08-1999
Publisher: The Optical Society
Date: 08-08-2011
DOI: 10.1364/OL.36.003073
Publisher: Elsevier BV
Date: 09-1995
Publisher: American Physical Society (APS)
Date: 04-1986
Publisher: IOP Publishing
Date: 28-08-1981
Publisher: American Physical Society (APS)
Date: 08-1992
Publisher: Frontiers Media SA
Date: 2013
Publisher: Springer Science and Business Media LLC
Date: 23-06-2011
Publisher: The Optical Society
Date: 06-1995
DOI: 10.1364/OL.20.001316
Abstract: We report excellent quantitative agreement between theoretical predictions and experimental observation of squeezing from a singly resonant second-harmonic-generating crystal. Limitations in the noise suppression imposed by the pump laser are explicitly modeled and confirmed by our measurements.
Publisher: IEEE
Date: 05-2013
Publisher: IEEE
Date: 05-2011
Publisher: American Physical Society (APS)
Date: 02-11-2006
Publisher: OSA
Date: 2007
Publisher: Springer Science and Business Media LLC
Date: 10-1989
DOI: 10.1007/BF00324176
Publisher: Elsevier BV
Date: 07-1991
Publisher: The Optical Society
Date: 04-1996
DOI: 10.1364/AO.35.001623
Publisher: American Physical Society (APS)
Date: 22-02-2007
Publisher: Springer Science and Business Media LLC
Date: 05-01-2015
DOI: 10.1038/NPHYS3202
Publisher: Springer Science and Business Media LLC
Date: 12-2008
DOI: 10.1038/NPHYS1145
Publisher: OSA
Date: 2007
Publisher: American Physical Society (APS)
Date: 07-1988
Publisher: IOP Publishing
Date: 03-11-2014
Publisher: IEEE
Date: 05-2011
Publisher: American Physical Society (APS)
Date: 13-06-1994
Publisher: Springer Science and Business Media LLC
Date: 03-02-2013
Publisher: Springer Science and Business Media LLC
Date: 03-12-2011
Publisher: Elsevier BV
Date: 11-1982
Publisher: Springer Science and Business Media LLC
Date: 09-1992
DOI: 10.1007/BF00325014
Publisher: Springer Science and Business Media LLC
Date: 28-08-2012
DOI: 10.1038/NCOMMS2033
Publisher: IOP Publishing
Date: 14-01-2002
Publisher: IEEE
Date: 06-2009
Publisher: American Physical Society (APS)
Date: 06-1997
Publisher: European Optical Society
Date: 09-06-2006
Publisher: American Physical Society (APS)
Date: 07-02-2006
Publisher: Springer Science and Business Media LLC
Date: 09-1992
DOI: 10.1007/BF00325008
Publisher: IEEE
Date: 05-2013
Publisher: IEEE
Date: 05-2011
Publisher: SPIE
Date: 11-02-2010
DOI: 10.1117/12.840782
Publisher: The Optical Society
Date: 10-1995
Publisher: The Optical Society
Date: 1993
Publisher: SPIE
Date: 07-04-2006
DOI: 10.1117/12.682631
Publisher: The Optical Society
Date: 02-1989
Publisher: American Physical Society (APS)
Date: 13-02-2002
Publisher: IEEE
Date: 08-2011
Publisher: Pleiades Publishing Ltd
Date: 05-2003
DOI: 10.1134/1.1576832
Publisher: IOP Publishing
Date: 04-03-2011
Publisher: PUBLISHED BY IMPERIAL COLLEGE PRESS AND DISTRIBUTED BY WORLD SCIENTIFIC PUBLISHING CO.
Date: 02-2007
Publisher: Informa UK Limited
Date: 11-1990
Publisher: Wiley
Date: 17-02-2010
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 1994
DOI: 10.1109/3.362718
Publisher: IOP Publishing
Date: 31-10-2002
Publisher: IOP Publishing
Date: 23-05-2002
Publisher: SPIE
Date: 28-05-2001
DOI: 10.1117/12.468702
Publisher: IOP Publishing
Date: 14-07-1980
Publisher: The Optical Society
Date: 11-11-2010
Publisher: Springer Science and Business Media LLC
Date: 07-01-2016
DOI: 10.1038/SREP19078
Abstract: Neurons are classified according to action potential firing in response to current injection. While such firing patterns are shaped by the composition and distribution of ion channels, modelling studies suggest that the geometry of dendritic branches also influences temporal firing patterns. Verifying this link is crucial to understanding how neurons transform their inputs to output but has so far been technically challenging. Here, we investigate branching-dependent firing by pruning the dendritic tree of pyramidal neurons. We use a focused ultrafast laser to achieve highly localized and minimally invasive cutting of dendrites, thus keeping the rest of the dendritic tree intact and the neuron functional. We verify successful dendrotomy via two-photon uncaging of neurotransmitters before and after dendrotomy at sites around the cut region and via biocytin staining. Our results show that significantly altering the dendritic arborisation, such as by severing the apical trunk, enhances excitability in layer V cortical pyramidal neurons as predicted by simulations. This method may be applied to the analysis of specific relationships between dendritic structure and neuronal function. The capacity to dynamically manipulate dendritic topology or isolate inputs from various dendritic domains can provide a fresh perspective on the roles they play in shaping neuronal output.
Publisher: OSA
Date: 2007
Publisher: Informa UK Limited
Date: 20-03-2006
Publisher: IEEE
Date: 2006
Publisher: American Physical Society (APS)
Date: 08-1991
Publisher: The Optical Society
Date: 06-05-2008
DOI: 10.1364/OE.16.007369
Abstract: We demonstrate experimentally the delay of squeezed light and entanglement using Electromagnetically Induced Transparency (EIT) in a rubidium vapour cell. We perform quadrature litude measurements of the probe field and find no appreciable excess noise from the EIT process. From input squeezing of 3.2+/-0.5 dB at low sideband frequencies, we observed the survival of 2.0+/-0.5 dB of squeezing at the EIT output. By splitting the squeezed light on a beam-splitter, we generated biased entanglement between two beams. We transmit one of the entangled beams through the EIT cell and correlate the quantum statistics of this beam with its entangled counterpart. We experimentally observed a 2.2+/-0.5 micros delay of the biased entanglement and obtained a preserved degree of wavefunction inseparability of 0.71+/-0.01, below the unity value for separable states.
Publisher: IOP Publishing
Date: 18-01-2008
Publisher: American Physical Society (APS)
Date: 27-04-2010
Publisher: SPIE
Date: 15-06-2020
DOI: 10.1117/12.2573217
Publisher: IOP Publishing
Date: 04-03-2011
Publisher: The Optical Society
Date: 15-05-1986
DOI: 10.1364/AO.25.001653
Publisher: SPIE
Date: 16-05-2003
DOI: 10.1117/12.497081
Publisher: OSA
Date: 2016
Publisher: American Association for the Advancement of Science (AAAS)
Date: 25-07-2008
Abstract: Position and momentum were the first pair of conjugate observables explicitly used to illustrate the intricacy of quantum mechanics. We have extended position and momentum entanglement to bright optical beams. Applications in optical metrology and interferometry require the continuous measurement of laser beams, with the accuracy fundamentally limited by the uncertainty principle. Techniques based on spatial entanglement of the beams could overcome this limit, and high-quality entanglement is required. We report a value of 0.51 for inseparability and 0.62 for the Einstein-Podolsky-Rosen criterion, both normalized to a classical limit of 1. These results are a conclusive optical demonstration of macroscopic position and momentum quantum entanglement and also confirm that the resources for spatial multimode protocols are available.
Publisher: Elsevier BV
Date: 12-1995
Publisher: Frontiers Media SA
Date: 05-2017
Publisher: OSA
Date: 2007
Publisher: American Physical Society (APS)
Date: 04-1995
Start Date: 06-2003
End Date: 05-2008
Amount: $1,450,370.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2008
End Date: 12-2009
Amount: $250,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2012
End Date: 12-2015
Amount: $430,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2009
End Date: 12-2012
Amount: $360,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2002
End Date: 12-2007
Amount: $1,100,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 07-2003
End Date: 07-2006
Amount: $43,400.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2010
End Date: 12-2011
Amount: $455,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2003
End Date: 08-2003
Amount: $1,184,640.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2006
End Date: 12-2006
Amount: $177,900.00
Funder: Australian Research Council
View Funded ActivityStart Date: 12-2003
End Date: 12-2004
Amount: $30,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 03-2004
End Date: 10-2004
Amount: $15,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 2003
End Date: 03-2011
Amount: $16,950,000.00
Funder: Australian Research Council
View Funded ActivityStart Date: 05-2011
End Date: 05-2012
Amount: $150,000.00
Funder: Australian Research Council
View Funded Activity