ORCID Profile
0000-0002-2446-4841
Current Organisations
Athens University Medical School
,
University College Cork
,
University of Lincoln
,
Ηellenic Army Academy
,
Biomedical Sciences Research Center Alexander Fleming
,
Ancilia Biosciences
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Publisher: Elsevier BV
Date: 11-2022
DOI: 10.1016/J.RADI.2022.07.002
Abstract: The Radiography Research Ethics Standards for Europe (RRESFE) project aims to provide a cross-sectional snapshot of current research ethics systems, processes, and awareness of such, across Europe together with identifying the associated challenges, education, and training needs. A cross-sectional online survey targeting radiography researchers in Europe was conducted. Data collection took place between April 26 and July 12, 2021, using a snowball s ling approach. Descriptive and analytical statistics were used to identify trends in research ethics frameworks across Europe. 285 responses were received across 33 European and 23 non-European countries. Most (n = 221 95%) European respondents stated ethics approval is required before commencing research in their country. Requirements around research ethics approval and awareness of such requirements varied by European region (X Respondents from countries with longer programme durations/availability of multiple programme lengths, availability of postgraduate training, and establishment of European Qualifications Framework Level 6 were generally associated with less uncertainty and more comprehensive research ethics requirements. Results are informative of the current status of research ethics within evidence-based radiography.
Publisher: Springer Science and Business Media LLC
Date: 28-11-2008
Abstract: Complexity is a key problem when visualizing biological networks as the number of entities increases, most graphical views become incomprehensible. Our goal is to enable many thousands of entities to be visualized meaningfully and with high performance. We present a new visualization tool, Arena3D, which introduces a new concept of staggered layers in 3D space. Related data – such as proteins, chemicals, or pathways – can be grouped onto separate layers and arranged via layout algorithms, such as Fruchterman-Reingold, distance geometry, and a novel hierarchical layout. Data on a layer can be clustered via k-means, affinity propagation, Markov clustering, neighbor joining, tree clustering, or UPGMA ('unweighted pair-group method with arithmetic mean'). A simple input format defines the name and URL for each node, and defines connections or similarity scores between pairs of nodes. The use of Arena3D is illustrated with datasets related to Huntington's disease. Arena3D is a user friendly visualization tool that is able to visualize biological or any other network in 3D space. It is free for academic use and runs on any platform. It can be downloaded or lunched directly from arena3d.org . Java3D library and Java 1.5 need to be pre-installed for the software to run.
Publisher: Elsevier BV
Date: 11-2022
DOI: 10.1016/J.RADI.2022.07.004
Abstract: The Radiography Research Ethics Standards for Europe (RRESFE) project aimed to provide a cross-sectional view of the current state of radiography research ethics across Europe. This included investigating education and training in research ethics, and identifying the key challenges and potential improvements associated with using existing research ethics frameworks. This cross-sectional online survey targeting radiography researchers in Europe was conducted between April 26 and July 12, 2021. Descriptive and analytical statistics were used to identify research ethics education and training trends. Content analysis of qualitative responses was employed to identify significant challenges and proposed improvements in research ethics frameworks of practice. There were 232 responses received across 33 European countries. Most (n = 132 57%) respondents had received some research ethics training however, fewer participants had received training on safeguarding vulnerable patients (n = 72 38%), ersity and inclusivity (n = 62 33%), or research with healthy volunteers (n = 60 32%). Training was associated with a greater perceived importance of the need for research ethics review (p = 0.031) and with the establishment of EQF Level 6 training (p = 0.038). The proportion of formally trained researchers also varied by region (p = <0.001). Time-to-ethics-approval was noted as the biggest challenge for professionals making research ethics applications. Early and universal integration of research-oriented teaching within the radiography education framework which emphasises research ethics is recommended. Additionally, study findings suggest research ethics committee application and approval processes could be further simplified and streamlined. The survey contributes to a growing body of knowledge surrounding the importance of education and training in research ethics for assuring a high standard of research outputs in Radiography and has identified hurdles to obtaining research ethics approval for further investigation and address.
Publisher: Springer Science and Business Media LLC
Date: 02-2012
Abstract: Keeping up-to-date with bioscience literature is becoming increasingly challenging. Several recent methods help meet this challenge by allowing literature search to be launched based on lists of abstracts that the user judges to be 'interesting'. Some methods go further by allowing the user to provide a second input set of 'uninteresting' abstracts these two input sets are then used to search and rank literature by relevance. In this work we present the service 'Caipirini' ( caipirini.org ) that also allows two input sets, but takes the novel approach of allowing ranking of literature based on one or more sets of genes. To evaluate the usefulness of Caipirini, we used two test cases, one related to the human cell cycle, and a second related to disease defense mechanisms in Arabidopsis thaliana . In both cases, the new method achieved high precision in finding literature related to the biological mechanisms underlying the input data sets. To our knowledge Caipirini is the first service enabling literature search directly based on biological relevance to gene sets thus, Caipirini gives the research community a new way to unlock hidden knowledge from gene sets derived via high-throughput experiments.
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United States of America
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: Greece
Location: United Kingdom of Great Britain and Northern Ireland
No related grants have been discovered for Sophie Jayne Willis.