ORCID Profile
0000-0003-4268-9419
Current Organisations
Universidade Federal do Rio Grande do Norte
,
Universidade do Minho
,
ICVS/3B's PT Associate Laboratory
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Publisher: Elsevier BV
Date: 08-2007
Publisher: SAGE Publications
Date: 14-06-2013
Abstract: In recent years, progress in the field of hybrid materials has been accelerated through use of the sol–gel process for creating materials and devices, which benefit from the incorporation of both inorganic and organic components. In this work, organic–inorganic hybrid membranes were prepared from tetraethoxysilane and a blend system composed of chitosan and soy protein. By introducing a small amount of siloxane bond into the chitosan/soy protein system, the chitosan/soy protein hybrid membranes were improved in terms of structure, topography and mechanical properties. It appears that the chitosan/soy protein hybrid membranes were formed by discrete inorganic moieties entrapped in the chitosan/soy protein blend, which improved the stability and mechanical performance assessed by the dynamic mechanical analysis as compared to chitosan/soy protein membrane. Also, in vitro cell culture studies evidenced that the chitosan/soy protein hybrid membranes are non-cytotoxic over a mouse fibroblast-like cell line. The hybrid membranes of silane-treated chitosan/soy protein developed in this work have potential in biomedical applications, including tissue engineering.
Publisher: SAGE Publications
Date: 09-2013
Abstract: Corrigendum to article ‘Hybrid biodegradable membranes of silane-treated chitosan/soy protein for biomedical applications’ by Simone S Silva, Joaquim M Oliveira, Johan Benesch, Sofia G Caridade, João F Mano, and Rui L Reis (2013), Journal of Bioactive and Compatible Polymers 28(4) 385-397, DOI: 10.1177/0883911513490361 . On page numbers 301, 385 and back cover, the last author’s name was misspelled as RUI R REIS. The correct name is RUI L REIS.
Publisher: Wiley
Date: 02-06-2008
Abstract: Surface modification of biomaterials is a way to tailor cell responses whilst retaining the bulk properties. In this work, chitosan membranes were prepared by solvent casting and treated with nitrogen or argon plasma at 20 W for 10-40 min. AFM indicated an increase in the surface roughness as a result of the ongoing etching process. XPS and contact angle measurements showed different surface elemental compositions and higher surface free energy. The MTS test and direct contact assays with an L929 fibroblast cell line indicated that the plasma treatment improved the cell adhesion and proliferation. Overall, the results demonstrated that such plasma treatments could significantly improve the biocompatibility of chitosan membranes and thus improve their potential in wound dressings and tissue engineering applications.
No related grants have been discovered for Simone Silva.