The University of Queensland

Organisation

Grant Count
5

Highest Funding Involved
$22,550,000.00

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Related Instruments

Instrument

7T Magnetom

Description:
CAI acquired the first human images in the southern hemisphere on a 7 Tesla whole body MRI scanner, on February 14th 2014. The Siemens Healthcare system is the first to be installed in Australia and is also the Flagship instrument of the National Imaging Facility (NIF). Key technical features of the system include a high-performance gradient with multi-receive and multi-transmit radiofrequency capabilities, which further increase sensitivity. The 7T will be used for a broad range of applications, including neuroscience, engineering, imaging and theranostics. Clinical applications that will benefit from the high spatial resolution achievable with this instrument include Alzheimer’s and Parkinson’s diseases, multiple sclerosis, epilepsy, musculoskeletal and liver diseases. In addition to this state-of-the art equipment, a multi-disciplinary team of scientists and engineers contribute their expertise to studies run on the 7T. View the gallery of 7T research images here. A few facts about the 7T The system was delivered in November 2013 The 7T weighs 38 tonnes 20,000 litres of liquid Helium were used to cool down the magnet to  -270°C The 7T uses the latest Magnetom platform, engineered by Siemens For more information, please contact the Facility Manager.
Instrument

Bruker Avance 16.4T MRI

Description:
The University of Queensland commissioned a state-of-the-art 16.4T MRI spectrometer in October 2006. This powerful system is the only one of its kind in the southern hemisphere and one of six in the world. The Bruker Ultrashield Plus 700 WB Avance NMR spectrometer has a vertical open bore diameter of 89 mm. It has an available space of up to 34 mm diameter, which is optimal for live mouse imaging and various types of ex vivosamples. The scanner is equipped with three types of gradient inserts: micro5, micro2.5 and mini0.5 which provide gradient strengths of 4.8, 2.5 and 0.5 mT/m/A. To achieve highest sensitivity, the scanner is equipped with new generation SAW and quadrature microimaging coils (5, 10, 15, 20, 25, 28 and 35 mm diameters). The 5-15 mm coils are suitable for imaging of excised (fixed tissue samples) such as brain, spinal cord and biopsy samples. The 20-35 mm coils are dedicated for mouse live imaging. The 16.4T is also equipped with High Resolution Magic Angle Spectroscopy (HR-MAS), which can be used to obtain 1H, 13C and 31P spectroscopy information from biopsy samples. The current 16.4T configuration is approximately twice as sensitive as the highest human MRI scanner (7T) available at CAI, and is predominantly used for microimaging, in particular, for in vivo / ex vivomouse imaging and spectroscopy. Specific applications include high-resolution diffusion imaging, susceptibility-weighted imaging and 19F imaging. Examples of imaging projects include: Diffusion microimaging of fixed embryo, brain, breast and prostate cancer tissue samples. Longitudinal studies of mouse models of spinal cord injury, multiple sclerosis, epilepsy and Alzheimer's disease. Detection of abnormal brain development using diffusion imaging and fibretracking. Functional kidney and cardiac imaging HR-MAS study of liver and brain metabolites  For further information, please contact the Facility Manager.
Instrument

Inveon PET-CT

Description:
The Inveon multimodality PET-CT imaging scanner (Siemens) is capable of providing three dimensional CT and PET images of live mouse and rat as well as fixed samples. The system can deliver high resolution CT images (18F, 11C, 64Cu). For information about the features of this instrument, please contact the Facility Manager.
Instrument

Bruker BioSpec 94/30 US/R MRI

MRIB94T

Description:
The Bruker Biospec MRI scanner consists of a 9.4 Tesla, 300 mm ultrashield refrigerated 30 cm magnet interfaced to a scalable Bruker Avance III spectrometer that allows unparalleled flexibility for MRI scanning of small and medium sized research animals and other samples. The system incorporates a cryoprobe, which enables maximum signal and image quality to be achieved for rodent mouse brain imaging. The system also includes 8 parallel RF transmit and receive channels for multi-coil phased array imaging and numerous coils to investigate nuclei other than standard protons or "water" imaging, notably carbon-13 coils to investigate metabolism, sodium-23 coils to investigate cell viability, phosphorus-31 coils to investigate tissue energetics and fluorine-19 coils for labelling of targeted tracers. This system offers new potential for advancing preclinical research and molecular imaging in national and international researchers collaboration within at the University of Queensland and is available for use through the Australian National Imaging Facility: www.anif.org.au. The system was funded with assistance from the Queensland State Government under the Australian Commonwealth Government's Education Investment Fund scheme. SPECTROMETER UQ Bruker 9.4T, 30cm bore Hardware = AVANCE III IPSO Controller Gradient Supervisor Unit tty04 Automatic hardware identification (HWIDS) PN=H14176, SN=0217 Parallel Transmit (PEX/MUX) PN=H12592, SN=0015 GRADIENT DPP Preemphasis, GRASI Control Unit Interface Gradient Coils BGA20S (128,200 Hz/cm), with XYZ shims BGA12S (285,000 Hz/cm, BFR W3307165/0048) with XYZ shims Gradient Amplifiers 3 x IECO gradient amplifiers (IECO 300A 500V, a.k.a. IECO_400_700) SHIM TOSI interface tty01 Shim Power Supply Bruker Shim Power Supply (BSPS 66010), Shims Z0, 2XY, YZ, X2-Y2, XZ, Z2 Max current = 10A and Max Voltage = 60.0V for each shim coil 6 channels Total Amps = 25.0A RF (transmit) Bruker linear amplifiers BLA1000 (1 kW) IE 15 – 400MHz, PN=W1345501, SN=0284 BLA1000 (1 kW) IE 15 – 400MHz, PN=W1345524, SN=0023 BLA2H500 (500 W) 400 – 500 MHz PN=W1345508, SN=0034 BLA2H500 (500 W) 400 – 500 MHz PN=W1345508, SN=0032 BLA2H500 (500 W) 400 – 500 MHz PN=W1345508, SN=0033 BLA2H500 (500 W) 400 – 500 MHz PN=W1345508, SN=0031 Bruker Preamplifier HPPR Cover module PN=Z103945, SN=00283, ECL=01.01 Preamplifier 1 HPLNA BB31P Preamplifier 1 HPLNA 19F1H Preamplifier 1 HPLNA 19F1H Preamplifier 1 HPLNA 19F1H Preamplifier 1 HPLNA 19F1H Signal generation, reception and digitisation AQS DRU-E Master Unit 1 PN=Z102520, SN=02977 RXAD400 PN=Z102116, SN=2747 ECL=05.01 DRU-E PN=Z102520, SN=02938 RXAD400 PN=Z102116, SN=2724, ECL=05.01 SGU/2 400 PN=Z103080 SN=03581 ECL=02.07 SGU/2 400 PN=Z103080 SN=03576 ECL=02.07 SGU/2 400 PN=Z103080 SN=03579 ECL=02.07 Pulse Splitter PN=Z104431 SN=00200 ECL=01.00 AQS2M - 1 DRU-E Master Unit 2 PN=Z102520 SN=02978 RXAD PN=Z102116 SN=2745 ECL=05.01 DRU-E PN=Z102520, SN=02980 RXAD400 PN=Z102116, SN=2744, ECL=05.01 DRU-E PN=Z102520, SN=02979 RXAD400 PN=Z102116, SN=2727, ECL=05.01 DRU-E PN=Z102520, SN=02936 RXAD400 PN=Z102116, SN=2726, ECL=05.01 DRU-E PN=Z102520, SN=02937 RXAD400 PN=Z102116, SN=2725, ECL=05.01 DRU-E PN=Z102520, SN=02931 RXAD400 PN=Z102116, SN=2746, ECL=05.01 RF Splitter PN=Z104432 SN=00207 ECL=02.01 AQS2M-2 SGU/2 400 PN=Z103080 SN=03603 ECL=02.07 SGU/2 400 PN=Z103080 SN=03620 ECL=02.07 SGU/2 400 PN=Z103080 SN=03623 ECL=02.07 SGU/2 400 PN=Z103080 SN=03629 ECL=02.07 SGU/2 400 PN=Z103080 SN=03625 ECL=02.07 SGU/2 400 PN=Z103080 SN=03633 ECL=02.07 SGU/2 400 PN=Z103080 SN=03575 ECL=02.07 RF Connection RF cable connections (detected by 'confamp') -------------------------------------------------------------------- SGU1 NORM output -> input 1 of transmitter 2 (BLA1000 IE 15-400MHZ INR W1345524/0023 at TCP/IP 149.236.99.245) SGU1 AUX  output -> open SGU2 NORM output -> input 1 of transmitter 1 (BLA1000 IE 15-400MHZ W1345501/0284 at TCP/IP 149.236.99.246) SGU2 AUX  output -> input 2 of transmitter 2 (BLA1000 IE 15-400MHZ INR W1345524/0023 at TCP/IP 149.236.99.245) SGU3 NORM output -> input 1 of transmitter 4 (BLA2H500 E 400-500MHZ W1345508/0032 at TCP/IP 149.236.99.242) SGU3 AUX  output -> open SGU4 NORM output -> input 2 of transmitter 4 (BLA2H500 E 400-500MHZ W1345508/0032 at TCP/IP 149.236.99.242) SGU4 AUX  output -> open SGU5 NORM output -> input 1 of transmitter 3 (BLA2H500 E 400-500MHZ W1345508/0034 at TCP/IP 149.236.99.243) SGU5 AUX  output -> open SGU6 NORM output -> input 2 of transmitter 3 (BLA2H500 E 400-500MHZ W1345508/0034 at TCP/IP 149.236.99.243) SGU6 AUX  output -> open SGU7 NORM output -> input 1 of transmitter 5 (BLA2H500 E 400-500MHZ W1345508/0033 at TCP/IP 149.236.99.241) SGU7 AUX  output -> open SGU8 NORM output -> input 2 of transmitter 5 (BLA2H500 E 400-500MHZ W1345508/0033 at TCP/IP 149.236.99.241) SGU8 AUX  output -> open SGU9 NORM output -> input 1 of transmitter 6 (BLA2H500 E 400-500MHZ W1345508/0031 at TCP/IP 149.236.99.240) SGU9 AUX  output -> open SGU10 NORM output -> input 2 of transmitter 6 (BLA2H500 E 400-500MHZ W1345508/0031 at TCP/IP 149.236.99.240) SGU10 AUX  output -> open Blanking cable connections (detected by 'confamp') -------------------------------------------------------------------- transmitter 1 (BLA1000 IE 15-400MHZ W1345501/0284 at TCP/IP 149.236.99.246) amplifier B-1000W uses blanking 2 transmitter 1 (BLA1000 IE 15-400MHZ W1345501/0284 at TCP/IP 149.236.99.246) amplifier B-300W uses blanking 2 transmitter 2 (BLA1000 IE 15-400MHZ INR W1345524/0023 at TCP/IP 149.236.99.245) amplifier B-1000W uses blanking 1 transmitter 2 (BLA1000 IE 15-400MHZ INR W1345524/0023 at TCP/IP 149.236.99.245) amplifier B-300W uses blanking 1 transmitter 3 (BLA2H500 E 400-500MHZ W1345508/0034 at TCP/IP 149.236.99.243) amplifier 1H-500W uses blanking 6 transmitter 3 (BLA2H500 E 400-500MHZ W1345508/0034 at TCP/IP 149.236.99.243) amplifier 1H-500W uses blanking 7 transmitter 4 (BLA2H500 E 400-500MHZ W1345508/0032 at TCP/IP 149.236.99.242) amplifier 1H-500W uses blanking 4 transmitter 4 (BLA2H500 E 400-500MHZ W1345508/0032 at TCP/IP 149.236.99.242) amplifier 1H-500W uses blanking 5 transmitter 5 (BLA2H500 E 400-500MHZ W1345508/0033 at TCP/IP 149.236.99.241) amplifier 1H-500W uses blanking 8 transmitter 5 (BLA2H500 E 400-500MHZ W1345508/0033 at TCP/IP 149.236.99.241) amplifier 1H-500W uses blanking 9 transmitter 6 (BLA2H500 E 400-500MHZ W1345508/0031 at TCP/IP 149.236.99.240) amplifier 1H-500W uses blanking 10 transmitter 6 (BLA2H500 E 400-500MHZ W1345508/0031 at TCP/IP 149.236.99.240) amplifier 1H-500W uses blanking 11 LO cable connections (detected by 'confrecsel') -------------------------------------------------------------------- SGU1 -> Rf-Splitter input 1 (-> REC1) SGU2 -> SGU3 -> Rf-Splitter input 2 (-> REC1-8) Preamplifier connections (detected by 'confrecpre') -------------------------------------------------------------------- Tune-SGU1 -> HPLNA BB31P -> REC1 Tune-SGU1 -> HPLNA 19F1H -> REC1 Tune-SGU1 -> HPLNA 19F1H -> REC2 Tune-SGU1 -> HPLNA 19F1H -> REC2 Tune-SGU1 -> HPLNA 19F1H -> REC2
Instrument

Bruker Clinscan 7T MRI/PET

Description:
The world’s first Bruker ClinScan PET-MR scanner was commissioned at Centre for Advanced Imaging in late 2012 as part of the NCRIS funded National Imaging Facility UQ node. This system allows simultaneous acquisition of MRI and PET images of an animal or sample. The technology combines the exquisite structural and functional characterisation of tissue provided by MRI with the extreme sensitivity of PET imaging of metabolism and tracking of uniquely labeled cell types or cell receptors. The MRI system is comprised of a 7 Tesla, 30 cm bore superconducting magnet, with operating software identical to the Siemens clinical MRI platform. This enables the most direct translation of research outcomes from animals to humans, benefiting a wide range of biomedical and scientific research. The PET insert has been developed to provide optimal performance in the high magnetic field of the MRI system. Available to all Australian researchers, this flagship PET-MR is funded as part of the National Collaborative Research Infrastructure Strategy (NCRIS), with financial contribution from the Commonwealth Government of Australia, the Queensland State Government and The University of Queensland. For any enquiries about this instrument, please contact the Facility Manager.
Instrument

3T Magnetom Prisma

Description:
The Siemens Magnetom Prisma provides an upgraded system with new MRI applications to deliver higher anatomical detail. The facility has a wide range of coils, software and peripheral equipment to support research studies in neurology, cardiology, angiography, oncology, orthophaedics, paediatrics and cognitive neuroscience. The laboratory is also equipped with tools for cognitive neuroscience studies. For more information, please contact the Facility Manager.
Instrument

JEOL JCM-5000 NeoScope

NeoScope

Description:
The NeoScope is an imaging table top Scanning Electron Microscope that can reach 20,000 times magnification.
Hardware specification Magnification  - ×10 to ×40,000 Observation mode  - High vacuum mode, Low vacuum mode Electron source  - Small cartridge electron source Accelerating voltage  - 15kV, 10kV, 5kV Specimen stage  - Manual, X 35mm, Y 35mm Maximum specimen size  - 70mm Diameter 50mm Height Detector  - Secondary electron detector, Backscattered electron detector Data display  - Accelerating voltage, magnification, micron bar, micron value Digital image  - 1,280ｘ1,024 pixels, bmp, tif, jpg OS  - Windows® VISTA、Windows® 7 Automatic operation  - Electron source, focus, brightness, contrast, and astigmatism Composition  - Main console + RP (20L/min) Main console dimensions  - W492ｘD458ｘH434mm Electric power  - Single phase AC100V (400VA) 240V (1,100VA) 50Hz/60Hz Room temperature  - 15°C to 30°C Humidity  - 70％ or less Software specification JCM-5000 (NeoScope), Version 1.2.2, Copyright 2008-2010 JEOL Technics Ltd. Supporting equipment 1 x external workstation
Access available through hourly rate, fee-for-service, or special arrangement. All users must register for access to CMM facilities.
Instrument

Renishaw InVia Raman Microscope

Description:
The Renishaw Raman microscope was installed 2008 and offers three laser wavelengths for Raman vibrational analysis of bonds in oxides and organic specimens. The spectrometer is accurate to 1 wavenumber, and the laser spot may be positioned on the sample to a few microns. It is also possible to perform polarization, photoluminescence, and confocal experiments on this microscope.
Hardware specificationsMain magnet  - Bore size: 30cm- Field strength: 9.4T Gradient System  - BGA-20S - BGA-12S HP RF system   Lasers Argon green laser 514 nm; 50 mW He-Cd ultraviolet laser 325 nm; 20 mW. Diode near-infrared laser 785 nm; 300 mW Research Grade Leica microscope objectives 5x, 20x, 50x , 15x UV optimised objective, 40x UV optimised objective, Colour video camera. Manual XY sample stage. Automated XYZ mapping stage with joystick Detector           CCD- UV enhanced CCD array detector (576 x 384 pixels) Gratings 1800 lines/mm (514nm); 1200 lines/mm (785nm); 2400 lines/mm (325nm) Computer Window 7 Professional. Processor: Intel (R) core (TM), i7-4790 CPU, 3.60 GHz, 8.0 MB Software specifications Renishaw WiRE 4.4 instrument control and data acquisition software, fully integrated data analysis and presentation software with image capture software for white light. Galactic Industries Spectral ID Search Software, Renishaw Polymer database (used with Galactic Spectral ID Library Search), Renishaw Minerals database (used with Galactic Spectral ID Library Search), Renishaw silicon calibration kit, Polariser / Analyser 325nm, Line focus accessory (UV) Supporting equipment Optical table- kinetic system optical table
All users need to register in PPMS, complete a Project Application form, providing details of project name, Chief Investigator, fund numbers, risk assessment and other details.
Instrument

Hitachi Scanning Electron Microscope SU3500-B

SU3500-B

Description:
Lay-person description of instrument (100 words limit) The Hitachi SU3500 is a conventional tungsten emitter Scanning Electron Microscope (SEM). It is a variable pressure (VP) SEM capable of both high and low vacuum modes of operation. It is fitted with two electron detectors (ET-Secondary and Backscatter for both Low Vacuum and High Vacuum) with a very flexible and user-friendly stage arrangement that holds multiple specimens.
Hardware specifications Electron optics: electron gun: pre-centered cartridge tungsten filament accelerating voltage: 1.5 – 30 kV objective aperture: 5-position, click stop objective aperture Motorized stage: Eucentric 5-axis autorized stage Rotation: 360 ° Tilt: -20 – 90 ° Observation area: 130 mm in diameters (with rotation) Maximum height: 70 mm (WD=10 mm) Low vacuum mode: 6-650 Pa Imaging via conventional BSE detector Software specifications SEM SU3500 PC-SEM Ver.3.4 Supporting equipment SEM imaging BSE imaging VP-SEM imaging Other information SEM is owned by Vaxxas and generously shared with UQ.
To access CMM facilities, please could you create an account on PPMS using your UQ login details. Once you have created an account, then you will need to submit an online project on PPMS for the work that you want to do with your sample on the microscopes. When you have completed your instrument training and received a booking licence, as well as the relevant laboratory safety inductions, you can go ahead and book your instrument using the CMM booking database (PPMS).
Instrument

Hitachi TM4000Plus Tabletop Microscope

Description:
The TM4000 Plus is an imaging tabletop Scanning Electron Microscope that can reach 30,000 times magnification. A tungsten wire type electron source is used. It can be operated at 5, 10 or 15kV in either BSE, SE or Mix (BSE+SE) modes. It has a maximum sample size of 80mm (diameter) x 50mm (height). This SEM is easy to learn and to operate. The PID (handles) for this instrument record has been updated, the old PID is 10378.1/1682892.
Model name TM4000PlusMagnifications10× - 100,000× (Photographic magnification)25× - 250,000× (monitor display magnification)Accelerating voltage5 kV, 10 kV, 15 kV,Image signalBackscattered electronSecondary electronMix (Backscattered electron + Secondary electron) Backscattered electronVacuum mode BSE: Conductor/Standard/Charge-up reductionSE: Standard/Charge-up reductionMix: Standard/Charge-up reduction BSE: Standard/Charge-up reductionSample stage traverse X: 40 mm, Y: 35 mmMaximum sample size 80 mm (diameter), 50 mm (thickness)Electron gun Pre-centered cartridge tungsten filamentSignal detection system High-Sensitivity 4-segment BSE detectorHigh-Sensitivity Low-Vacuum SE detector (UVD) High-Sensitivity 4-segment BSE detectorEvacuation system(vacuum pump)Turbo molecular pump : 67 L/s×1 unitDiaphragm pump : 20 L/min×1 unitSize / weight Main unit (motorized stage): 330 (width)×614 (depth)×547 (height) mm, 54kgMain unit (manual stage): 330(width)×617(depth)×547(height) mm, 54kgDiaphragm pump: 144 (width)×270 (depth)×216 (height) mm, 5.5kg Software specifications: TM4000 Tabletop Microscope Version: Serial No. 187031-02 Operation Ver. 1.5 Control Ver.1.5
Instrument

Rigaku SmartLab 9kW X-Ray Diffractometer

Description:
Microdiffraction is a technique which allows diffraction measurements to be carried out selectively on small areas.  This method is essential for materials which are too small to be measured in a traditional X-ray diffraction beam or where mapping of the sample is required. The PID (handles) for this instrument record has been updated, the new PID is 102.100.100/636956.
The Rigaku SmartLab is a highly versatile XRD instrument and which features a 9 kW Cu rotating anode source; a variety of collimation options including 2 and 4 bounce Ge-Monochromators for HRXRD and capillary optics for micro diffraction; a cryo-stream (capillary/transmission optics only) that allows XRPD measurements from ca. 90 K to 600 K; a 5 axis goniometer, a domed furnace (reflectance geometry) that allows XRPD measurements from ambient to 1100 °C;  and a two-dimensional hybrid pixel array detector.  It can be configured to carry out a wide range of experiments on a wide range of sample types including: XRR measurements, in-plane and out-of-plane GI diffraction, texture analysis, reciprocal space mapping, HRXRD, microdiffraction and 2D mapping of samples. Hardware specifications: Installation of instrument: June 2015 9kW Cu rotating anode source Collimation options: 2- and 4-Bounce Ge monochromators for High-Resolution XRDCapillary optics for micro-diffraction Cryostream (Capillary/ Transmission optics only) that allows X-Ray Powder Diffraction measurements from ca. 90 degrees K to 600 degrees K 5-Axis Goniometer Domed Furnace (Reflectance Geometry) that allows X-Ray Powder Diffraction measurements from ambient to 1100 degrees C 2-Dimensional hybrid pixel array detector Software specifications: Control Software: SmartLab Guidance; Data Processing Software: Standard Data Processing, PDXL; Data Display Software: Thin-Film Data Processing, Profile Viewer, 3D Explore; Analysis Software: GlobalFit.