Statistical methods for identifying structural variation in tumour genomes using Next Generation sequencing

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/637357

Funding Status
Closed

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Funded Activity Summary

New DNA sequencing technology can sequence a tumour genome affordably in 2 weeks. This re-sequencing data can be used to find small mutations and large-scale chromosomal rearrangements that together are the drivers of cancer. These may one day be used to guide cancer therapy. This project will develop new algorithms for finding mutations and apply these to discover the genetic basis of drug resistance in a model lymphoma system.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $243,458.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Bioinformatics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Next Generation sequencing | bioinformatics | cancer | mutation | mutation detection | structural genome variation | understanding genome structure and evolution

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