Explaining the selection of gluten peptides toxic in coeliac disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/637349

Funding Status
Closed

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Funded Activity Summary

Immune response genes shape the molecular specificity of immune responses, and some play a critical role in causing disease. Coeliac disease caused by gluten in food is very tighly linked to such genes. Discovery of the components of gluten in each genetic variant of coeliac disease will allow us to study how the gluten immune reaction in coeliac disease is controlled, and will be the basis of better diagnostic tests and therapies.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $704,117.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Immunogenetics (incl. Genetic Immunology)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Coeliac disease | Functional genomics | Gluten toxicity | Immunopathology | Immunotherapy | T-cell immunodominace heirarchy

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