Dissecting the Molecular Basis of the Malaria Parasite-Erythrocyte Tight Junction Complex

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/637340

Funding Status
Closed

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Funded Activity Summary

The parasites that cause malaria disease must invade the human red blood cell to complete their lifecycle. Invasion requires the formation of a complex interface between parasite and red cell called the Tight Junction. However, this structure's molecular makeup is entirely unknown. Our research will use a combination of state-of-the-art microscopy and genetics to define, for the first time, the junction's organization, providing a critical platform for the development of a malaria vaccine.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $547,356.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Basis of disease in falciparum malaria | Electron microscopy | Laser scanning confocal microscopy (LSCM) | Malaria | Malaria vaccine | Malaria vaccines | Plasmodium falciparum | Plasmodium falciparum malaria | Protection against malarial disease

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