MicroRNA networks that safeguard the functional program of regulatory T cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/637338

Funding Status
Closed

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Funded Activity Summary

A newly discovered group of molecules termed microRNAs are thought to function as rheostats for the activity of genes. We have shown that these molecules are critical for the function of an immune cell type termed regulatory T cells. Without these cells, the immune system is unable to prevent uncontrolled and destructive inflammation. This proposal aims to utilize diverse technologies to uncover the precise molecular mechanisms by which microRNAs safeguard the function of regulatory T cells.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $457,941.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autoimmunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

gene discovery | gene expression | immune regulation | immunoregulation | inflammatory disease | mRNA expression | microRNA | molecular genetics | regulatory T cells

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