Role of endogenous Bcl-2 family proteins in acute myeloid leukaemia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/637326

Funding Status
Closed

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Funded Activity Summary

Programmed cell death (apoptosis) is crucial for health. Impaired apoptosis can lead to cancer. In blood cancers, mutations that disrupt apoptosis allow cells to survive whilst acquiring additional mutations. Moreover, the mutations prevent most drug treatments for cancer, which act by inducing apoptosis, from working effectively. Our research will investigate the role of apoptosis in tumour development and in sustaining tumour growth. The results will help to identify new cancer therapies.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $474,033.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematological Tumours

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

apoptosis | blood | cancer and related disorders | cancer chemotherapy | early cancer | gene knock-out | haemopoiesis | leukaemia | leukaemias

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