Targeting CD40L(CD154) on dendritic cells for CD8 T cell-mediated immunity and tolerance

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/637324

Funding Status
Closed

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Funded Activity Summary

Killer T cells fight infection but also participate in transplant rejection. Activation of killer T cells often requires helper T cells. However, in the absence of helper cells, we have found an alternative pathway by which killer cells can be activated. We will explore this new pathway in enhancing vaccine responses and in modulating transoplant rejection.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $558,441.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

costimulation | dendrtic cells | infection immunity | transplantation | type i diabetes | vaccine

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