A novel patch-fluorimetry technique for investigating structural changes during gating of mechanosensitive ion channnels

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/635525

Funding Status
Closed

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Funded Activity Summary

Membrane proteins, especially membrane channels play an important role in regulating the flow of substances across the cell. Dysfunction in these channels can lead to a variety of diseases. Thus approximately 60% of drug development is targeted against such proteins. In our research, we are looking at membrane channels found in bacteria. Understanding the function of these channels will help us develop novel anti-bacterial agents. It will also aid to understand a role of ion channels in disease.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $387,018.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biological Physics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antimicrobial resistance | fluorescence microscopy | ion channel dysfunction | ion channels | laser scanning confocal microscopy (LSCM) | lipid bilayers | muscular dystrophy | patch clamping

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