Characterization of Haemopoietic Lineage Determining Genes

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/634494

Funding Status
Closed

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Funded Activity Summary

Haemopoiesis is the process by which blood cells develop from stem cells. This process is tightly regulated and is dependant upon the appropriate expression of genes at each developmental stage within various lineages. Our work focuses on two genes (Mlf1 and Hls5) that are involved in determining lineage commitment and affect the expression of key hemopoietic regulators. If these genes are aberrantly expressed leukemias and other blood disorders can develop.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $631,021.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Animal models for haemopoietic commitment | Biochemistry | Haemopoiesis | Protein structure -activity relationships | Protein-protein interactions | Transcriptional regulation | anaemia | erythroleukemia | haemopoietic stem cells | leukemia

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