Defintion of dystrophin functional domains according to exon boundaries to optimise splice switching therapies for DMD

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/634485

Funding Status
Closed

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Funded Activity Summary

Duchenne muscular dystrophy is a relentlessly progressive muscle wasting disorder, with a predictable outcome and no effective treatment. Splice manipulation has the potential to reduce the severity of the disease, improve the quality of life for patients and reduce health care costs. The definition of dystrophin functional domains according to exon boundaries will allow the most effective treatment strategies for each mutation to be developed.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $520,765.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene and Molecular Therapy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Duchenne mucsular dystrophy | Duchenne muscular dystrophy | animal model | antisense oligonucleotide | child health | death | inherited disease | muscle degeneration | muscular dystrophy

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