Do activated retinal microglia mediate neurotoxicity in background diabetic retinopathy?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/634469

Funding Status
Closed

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Funded Activity Summary

Diabetic retinopathy, a frequent complication of Type 1 and Type 2 diabetes, is the commonest cause of blindness in working age individuals. Prior to the growth of blindness-causing new vessels in the eye we now know that there is a gradual loss of neurons in the retina. This project will investigate whether the resident immune cells in the retina, which are normally neuroprotective, become neurotoxic during episodes of systemic inflammation (e.g. bacterial or viral infections).

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $435,589.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Ophthalmology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Diabetes | Neurodegeneration | Ocular inflammation | Retinopathy | inflammation | microglia | retina

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