Towards Alternative Therapeutic Agents to Antibiotics for the Treatment of Helicobacter pylori Infections.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/634465

Funding Status
Closed

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Funded Activity Summary

The bacterium H. pylori, is the leading cause of gastric ulcers, infecting over half of the world population. Furthermore, patients infected with the bacteria exhibit an increased risk of developing gastric cancer, with 900,000 new cases diagnosed yearly. The current proposal will study an enzyme which allows the bacterium to evade the host's immune system. The work aims to develop inhibitors of the enzyme as therapeutic agents to treat peptic ulcers.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $787,286.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

enzyme inhibition | enzymes | gastric cancer | gastritis | helicobacter pylori | infectious disease | medicinal chemistry | protein structure

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