RGS5 signalling in cardiovascular and smooth muscle cell physiology

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/634334

Funding Status
Closed

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Funded Activity Summary

Cardiovascular diseases, including hypertension, remain one of the largest causes of morbidity and mortality in Western populations. We have identified a molecule, called Regulator of G protein signalling 5 (RGS5), which is involved in pathological vessel remodelling and in the regulation of blood pressure. This molecule is a prime candidate for drug development. We will study the precise role of RGS5 in cardiovascular disease models and regulatory pathways in cell systems.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $645,613.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

G protein coupled receptors | Signalling pathways | blood pressure regulation | cardiovascular disease | cardiovascular disease and hypertension | molecular basis of disease | pre-eclampsia-eclampsia, pregnancy induced hypertension | telemetry | vascular remodelling | vascular smooth muscle

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