Steroidogenic factor-1, a novel regulator of hepatic stellate cell function

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/632886

Funding Status
Closed

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Funded Activity Summary

Recently, we have discovered that steroidogenic factor-1, a specialized protein that directs cells to make steroid hormones, is present in cells in the liver called stellate cells. This may play a vital role in how the liver responds to damage and whether the liver will the scar and move on to cirrhosis. Our experiments will determine if this is so and how this system functions. This work will provide a basis for future treatments to improve or prevent cirrhosis in liver disease patients.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $589,458.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Amelioration of liver diseases | Chronic liver diseases | Development of novel therapies | Hepatic gene regulation | Hepatic stellate cells | Liver injury and inflammation | Nuclear receptors | Pathogenesis of liver diseases | Prevention of cirrhosis

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