Purinergic P2X7 Receptor as a Target for Antidepressant Drug Discovery

Funding Activity

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Funded Activity Summary

Depression is the most common mental disease. Around one million Australian adults and 100,000 young people live with depression each year resulting in significant economic, social and personal costs. Despite multiple treatments of depression, there are still several serious unmet needs with most current antidepressants showing limited effectiveness. We have identified a novel protein in the brain that represents an innovative approach to providing a platform for antidepressant drug discovery.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $567,760.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

Antidepressant Therapy | Basic Pharmacology | Biologically Active Molecules | Central Nervous System | Cytokine secretion | Depression | Drug Discovery | Purinergic receptors