Mast cells - bystanders or instigators of airway remodelling in asthma?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/632830

Funding Status
Closed

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Funded Activity Summary

Current asthma treatments have little effect on changes to the breathing tubes in our lungs. The tubes are thickened and stiffer, with more muscle, blood vessels, matrix and mucus. We propose that a particular inflammatory cell, called a mast cell, causes these changes to the breathing tubes and we will find out how it does that. Thus this project will establish why and how the changes to the breathing tubes happen in asthma and reveal how best to target and reverse-prevent them in the future.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $623,764.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

airway inflammation | airway remodelling | airway structural cells | asthma | cell migration | cell proliferation and differentiation | extracellular matrix deposition | mast cell products

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