Role of Lamin A-C in Osteoblastogenesis and Age-related Bone Loss

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/632766

Funding Status
Closed

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Funded Activity Summary

Osteoporosis prevalence in Australia has increased, especially in the older population. Patients with accelerated aging (Hutchinson Gilford) suffer from severe osteoporosis. A mutation in lamin A-C was identified as the cause of this disease. Therefore it could be the link between aging and bone loss. We will identify the role of lamin in bone biology. We will generate a new understanding of the connection between aging and bone loss and a new potential therapeutic target for senile osteoporosis

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $475,515.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Molecular Targets

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Age-related bone loss | Aging | Fractures | Lamins | Mesenchymal Stem Cells | Osteoblastogenesis | Osteoblasts | Osteoporosis | Progeria

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