Designer RNA-binding proteins for research and therapeutic purposes

Funding Activity

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Funded Activity Summary

It has become clear recently that ribonucleic acids play many roles in the switching on and off of genes in humans and other organisms. These molecules play roles in a number of diseases, including HIV-AIDS, hepatitis, and a large number of inherited disorders. We propose to build a library of protein molecules that can bind specifically to a wide range of RNA targets and modulate their function. These molecules have the capacity to act as therapeutics for a wide range of diseases.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $557,480.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biomolecular Modelling and Design

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Genetic diseases | Neurodegenerative diseases | RNA processing | RNA-binding proteins | Viral diseases | gene regulation | protein design | zinc finger proteins