The Role of Toll-like receptors in Diabetic Nephropathy

Funding Activity

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Funded Activity Summary

Diabetic nephropathy (DN) is the leading cause of chronic kidney disease globally and the No.1 cause of kidney failure requiring dialysis or transplantation in Australia. We are unsure why kidney scarring and failure develops in people with diabetes. Because of this, we have no specific treatments. Our studies suggest an immune receptor present in the kidney may be important. We aim to see whether absence of these receptors can prevent DN, thus identifying a specific target for treatment.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $740,452.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology and Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Diabetic nephropathy | Renal failure | Toll-like receptors | chronic kidney disease | fibrosis | inflammation | kidney disease | progression