Optimising the therapeutic efficacy of anti-inflammatory macrophages for use in chronic kidney diseases

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/632665

Funding Status
Closed

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Funded Activity Summary

Chronic kidney disease (CKD) is a major cause of death and morbidity in Australia. Current treatments that are able to delay progression for CKD are limited. As a consequence, more than 2300 additional Australians need kidney replacement each year and many more die of kidney failure. We have reduced and prevented injury in a mouse model of CKD by administering protective white blood cells - macrophages. This project will modify macrophages ex vivo to optimize them for use as a therapy for CKD.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: Project Grants

Funding Amount: $605,096.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology and Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anti-inflammatory macrophages | chronic kidney disease | fibrosis | interstitial inflammation | kidney failure | progression of chronic kidney disease

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