Bisphosphonate Treatment of Childhood Femoral Head Avascular Necrosis due to Perthes Disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/632532

Funding Status
Closed

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Funded Activity Summary

Perthes disease (PD) occurs following loss of blood supply to the hip (femoral head). It is a severe childhood disorder with over 250 new cases per year in Australia. PD results in flattening of the normally round femoral head and painful arthritis. The hip becomes flat because the bone is eaten by cells called osteoclasts. We will test if a medicine aimed at stopping these osteoclasts can prevent hip flattening. This should decrease the risk of arthritis and the need for hip replacement.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $1,368,242.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Orthopaedics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Avascular necrosis | Bisphosphonate therapy | Bisphosphonates | Children | Paediatric endocrinology | Paediatric orthopaedics | Perthes disease | Prevention of hip deformity

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