Gamma-Delta Tregs, CD8 Tregs and selected natural Tregs to treat renal injury

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/632519

Funding Status
Closed

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Funded Activity Summary

Chronic kidney disease (CKD) progresses due to ongoing damage to the kidney. We have identified three types of white cells that can reduce kidney damage in CKD. The first is a unique set of gamma-delta T cells that expand in the kidney and protect against injury. The second is a restricted set of CD8 T cell that can protect against kidney injury. The third are targeted natural regulatory T cells. These studies develop each of these three subsets as potential cellular therapies in CKD.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: Project Grants

Funding Amount: $605,096.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology and Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

chronic kidney disease | chronic renal failure | fibrosis | kidney failure | renal interstitial scarring | tubulointerstitial inflammation

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