Inhibitors of Secretory Phospholipases in Diet Induced Obese Rats

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/631534

Funding Status
Closed

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Funded Activity Summary

A new drug given to rats fed a high fat-carbohydrate diet shows very promising effects in preventing and treating abdominal obesity, insulin resistance, glucose intolerance, and other risk factors for diabetes and cardiovascular disease. This project will profile biochemical and pharmacological properties of the drug in more detail in order to track down molecular mechanisms of its action and potential therapeutic benefits, guided by studies on rats, biochemical markers, rat and human fat cells.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $581,051.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

abdominal obesity | anti-inflammatory | biochemistry | cardiovascular and diabetes type II risk factors | cardiovascular disease | diabetes | enzyme inhibition | inflammation | metabolic syndrome | obesity

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