Regulation of Bone Dynamics by Osteal Tissue Macrophages (Osteomacs)

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/631484

Funding Status
Closed

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Funded Activity Summary

There is a high demand for effective treatments to rebuild and replace lost bone in fracture repair and osteoporosis. We have described a discrete population of macrophages (classically immune defense cells) within the specialized tissues that line bones. We have shown that these bone tissue macrophages have a novel role in promoting the formation of new bone. This project grant will extend these observations and identify the clinical potential of bone tissue macrophages to treat bone disease.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $741,095.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Orthopaedics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Ageing | Bone growth and fracture healing | Bone loss | Macrophage | Osteoblast | Osteoclast | Osteoporosis | Skeletal disease | bone remodelling and osteogenesis | osteoimmunology

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