The role of subgenomic non-coding viral RNA in flavivirus pathogenicity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/631365

Funding Status
Closed

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Funded Activity Summary

Flaviviruses are transmitted by insects and pose a serious health threat to the Australian population. They can cause fever syndromes, encephalitis and death. We aim at better understanding of how these viruses cause disease. We are particularly interested in elucidating the role of small non-coding nucleic acid produced by flaviviruses in the viral pathogenicity. Ultimately, this deeper understanding should lead to the development of effective vaccines and antiviral therapies.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $555,325.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Infectious Diseases

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

Australian encephalitis and related flavivirus infections | Flavivirus | Microbiology - Virology | RNA structure and degradation | arbovirus diseases | flavivirus encephalitis | host response | host-pathogen interaction | virus replication

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