Molecular and cellular characterisation of schizophrenia associated dysfunction in microRNA biogenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/631057

Funding Status
Closed

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Funded Activity Summary

We have identified substantial changes in the biogenesis of microRNA in schizophrenia. These small non-coding molecules derived from junk DNA, play a significant role in genetic regulation, with each one capable of silencing hundreds of target genes. This has major implications for schizophrenia, which is known to involve substantial changes in gene activity. The project will identify the molecular basis of this alteration in gene silencing, and its biological implications for schizophrenia.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $496,205.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Mental Health

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Biological Psychiatry | Mental Health | Molecular Psychiatry | Neurodevelopmental disorders | PGP7 | Psychiatric Genetics | Psychiatric disorders | Psychosis | Schizophrenia

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