The pathogenesis of distinct endophenotypes of asthma is underpinned by the collaborative activation of specific PRRs.

Funding Activity

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Funded Activity Summary

Asthma is a chronic airway disease caused by inflammation. Although asthmatics can be sub-typed based on the type of inflammatory cells present in the lungs, medication specific for the treatment of these sub-types is not yet available. In this grant we will investigate the immune processes that orchestrate the development of the distinct inflammatory sub-types of asthma. This information will help us develop new therapies that will be tailored to target the appropriate type of inflammation.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $678,754.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Acute inflammation | Asthma | Asthma and respiratory diseases | Asthma disease induction and prevention | Eosinophils | Eosinophils and neutrophils | Innate immunity | Interleukins | Neutrophils | Obstructive airways disease