Identification of new therapeutic targets in neuroblastoma through ABCC transporter associated pathways.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/630608

Funding Status
Closed

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Funded Activity Summary

Neuroblastoma accounts for 15% of childhood cancer deaths. Children diagnosed over 1 year have survival rates below 40%. New research shows that certain genes previously implicated in drug resistance contribute to neuroblastoma development. We will investigate their role using a new neuroblastoma model and a range of biochemical and cell biology techniques. This research will improve our understanding of neuroblastoma biology and identify new therapeutic targets in this and other cancers.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $591,436.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Solid Tumours

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

childhood cancer | gene expression | lipidomics | metastasis | metastatic disease | mouse xenograft | tumour biology | tumour progression

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