Alcoholic chronic pancreatitis: induction, progression and reversal

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/630509

Funding Status
Closed

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Funded Activity Summary

Pancreatitis (inflammation of the pancreas) is a serious complication of alcohol abuse. Patients suffer from severe and often intractable abdominal pain, maldigestion and diabetes, We have recently shown that gut toxins (endotoxins) may act as a trigger factor for pancreatitis in alcoholics. The proposed project aims to characterise the effects of gut toxins on the pancreas during alcohol abuse so as to identify pathways that may be therapeutically targeted to prevent or retard the disease.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $632,211.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alcohol | Alcoholic pancreatitis | Bacterial endotoxaemia | Endotoxin | Pancreatic fibrosis | Pancreatic necroinflammation | Pancreatic stellate cells | Pancreatitis | Stellate cell activation

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