Investigating the action of clozapine on the epidermal growth factor system: implications for antipsychotic drug action

Funding Activity

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Funded Activity Summary

Current treatments for schizophrenia are ineffective for up to half of sufferers leaving the toxic drug clozapine as the only resort. This project aims to investigate if the unique effectiveness of clozapine is due to a novel action in brain cells that we have identified. The project will delineate this mechanism and from this may lead to the development of a new way of treating schizophrenia and insights into the causes of this disorder.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $364,535.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Psychiatry (incl. Psychotherapy)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

EGF-EGFR signalling | antipsychotic | antipsychotic drugs | growth factors-receptors | pathophysiology of schizophrenia | schizophrenia | schizophrenia and other psychoses