Interferon Regulatory Factor 6: a novel epithelial-specific regulator of mucosal inflammation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/628769

Funding Status
Closed

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Funded Activity Summary

Epithelial cells lining the respiratory and gastrointestinal tracts play pivotal roles in protecting us from infection. Inflammatory factors released by epithelial cells are important for fighting infection; however, they also contribute to chronic inflammatory diseases. We aim to understand how a protein called IRF6 regulates the inflammatory response of epithelial cells. The knowledge gained will identify new therapeutic approaches for inflammatory diseases.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $517,989.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Toll-like receptor | airway inflammation | cytokine | epithelial cells | gastrointestinal inflammation | infectious diseases | interferon | mucosal inflammation | transcription factor

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