Identification of a plasma factor of remote ischemic preconditioning and its effect on the proteome after heart surgery

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/628756

Funding Status
Closed

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Funded Activity Summary

Heart surgery with the heart placed into arrest causes inflammation and tissue damage due to interrupted circulation. We know that prior brief interruption and restoration of blood supply called remote ischemic preconditioning (IPC) can protect heart and lungs against damage. Our previous studies indicate that IPC involves a circulating factor that protects the tissue by optimizing energy preservation. This knowledge can be applied to organ transplants, protection from stroke and heart attack.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $385,197.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Surgery

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cardiac surgery | cardiopulmonary bypass | ischemia-reperfusion injury | plasma proteins | preventative medicine | reprefusion injury

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