Regulation of skeletal muscle AMP-activated protein kinase by glycogen

Funding Activity

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Funded Activity Summary

The enzyme AMP protein kinase has three parts (subunits) and is central to controlling the body's metabolism. We have discovered that one subunit is essential for tightly associating the enzyme with muscle glycogen which is a source of high energy and efficient metabolism. We will identify where the enzyme attaches to glycogen, and how diet and exercise alter this association. Understanding this could lead to new approaches for treating Type 2 diabetes where energy metabolism is disrupted.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $561,558.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Exercise Physiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

diabetes (type 2) | exercise | metabolism | muscle metabolism | protein kinases | protein localisation | skeletal muscle