Understanding the biosynthesis of complex polyketide lipid toxins in pathogenic mycobacteria

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/628640

Funding Status
Closed

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Funded Activity Summary

Some major infectious diseases such as tuberculosis are caused by bacteria that make very unusual lipids (fats) that can kill human cells or interfere with the human immune system. The aim of this project is to work out how bacteria make these lipids. This knowledge will open up new avenues for treatments to stop bacterial lipid production and prevent disease. There are also potential applications in harnessing the bacterial lipid machinery to make new drugs and a wide range of other chemicals.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $298,898.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Infectious Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Bairnsdale ulcer | Buruli ulcer | Mycobacteria | bacterial pathogen | extracellular toxins | immunoregulation | lipid biosynthesis | molecular pathogenesis | mycobacterial infection | skin ulcer

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