Sonic hedgehog signalling in Barrett s oesophagus

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/628635

Funding Status
Closed

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Funded Activity Summary

Barrett's oesophagus (BO) is a condition that arises in some patients with chronic reflux (heartburn) and increases the risk of developing cancer of the oesophagus. However, the exact mechanisms involved in its development are unknown. This project aims to investigate how a protein called sonic hedgehog might be involved using novel cell culturing techniques that allow us to model the growth of oesophageal tissue in the laboratory. This could lead to development of new therapies for treating BO.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $570,876.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Barrett's oesophagus | Sonic hedgehog signalling | epithelial biology | epithelial morphogenesis | gastro-oesophageal reflux | gastroenterology | intestinal metaplasia | oesophageal adenocarcinoma

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