The role of Scribble in Prostate Cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/628614

Funding Status
Closed

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Funded Activity Summary

Every cell in our body has an intrinsic orientation that is controlled by a universal set of genes known as polarity genes. Loss of this orientation is a common and early feature of cancer. We have identified the gene Scribble as a gene that controls cell orientation and is essential to prevent the development of prostate cancer. We propose experiments to discover how Scribble controls prostate cancer and whether it can be used to better predict outcome for prostate cancer patients.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $601,803.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Development, Proliferation and Death

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cell polarity | Prostate Biology | Prostate Cancer | Signalling pathways | Tissue Architecture | Tumour Suppressor | tumour metastasis and invasion | tumour suppressor

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