Repair of the nigrostriatal pathway by phenotype shift of dopamine neurones

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/628480

Funding Status
Closed

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Funded Activity Summary

Repairing the injured brain will depend on developing new cells that can form the correct cell type, make the right connections and be incorporated into normal brain circuitry. We have found that dopamine cells, which are lost in Parkinson's Disease, are being renewed in the adult rodent brain. This study is directed at finding factors that control this process and to exploit these factors therapeutically. We provide evidence that this can be used to treat Parkinson's Disease.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $561,558.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Parkinson's disease | Parkinson's disease, dopamine, substantia nigra | addiction, aging and dementia | basal ganglia disorders, movement disorders | calcium signalling, movement disorders | ion channels, potassium channels | nerve excitability, neurotoxicity | nervous system disorders, nervous system repai | neuronal differentiation, neurochemistry

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