Molecular analysis of myelodysplasia in the Nup98HoxD13 mouse model

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/628367

Funding Status
Closed

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Funded Activity Summary

Myelodysplastic syndrome is a preleukemic condition which is poorly understood and occuring at an increasing frequency. Unfortunately no targeted therapy exists. Two features of the disease are abnormal gene expression and abnormal cell death. We have a uniquely accurate model of this disease, and we plan to use it to investigate these two phenomena which will lead to greater understanding of the disease and new molecular targets for therapeutic agents to be developed and tested in our model.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $351,502.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Acute lymphoblastic leukemia | Acute myeloid leukemia | Apoptosis | Epigenetics | Myelodysplasia | Myelodysplastic syndrome

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