c-Jun N-terminal Kinase regulation of microtubule destabilizer, Stathmin - a novel cytoprotective pathway

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/628335

Funding Status
Closed

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Funded Activity Summary

The loss of heart muscle cells during heart attack and heart failure worsens the severity of heart disease. We will study how to protect heart muscle cells by identifying the molecules involved in controlling survival responses. We will use this knowledge to prevent heart muscle cells from dying when exposed to a range of normally harmful conditions. Our study has the potential to prevent heart muscle cell loss, improve heart function and prevent muscle damage in heart disease.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $550,230.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cardiac Ischaemia | Cell Death-Apoptosis | Dilated Cardiomyopathy | Kinase | Microtubules | Myocardial Infarction | Phosphorylation | c-Jun-JNK kinase

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