Hematopoietic transplants from autologous pluripotent cell sources

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/627156

Funding Status
Closed

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Funded Activity Summary

This proposal investigates the utility of two types of patient-derived stem cells for transplantation into blood. These are induced pluripotent stem cells that are reprogrammed from specialized tissues such as skin cells, and stem cells derived using the genetic material of oocytes or sperm only ( one-parent embryos). Using the mouse, we are looking at the ability of these cells to form normal blood lineages after transplantation, and to repair blood in a mouse model for beta-thalassemia.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Regenerative Medicine (incl. Stem Cells and Tissue Engineering)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cell differentiation | embryonic stem cells | epigenetics | hematopoietic stem cell differentiation | induced pluripotent stem cells | pluripotentiality | stem cell therapy | stem cell transplantation

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