Molecular analysis of pneumococcal pathogenesis

Funding Activity

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Funded Activity Summary

The pneumococcus is a major cause of bacterial pneumonia, sepsis and meningitis especially in children and the elderly. Antibiotic-resistant pneumococci are becoming more prevalent, and available vaccines have major shortcomings. We propose to identify and characterise the factors produced by this organism during infection that enable it to cause invasive disease. Such factors could be incorporated into protein-based pneumococcal vaccines currently under development.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2014

Funding Scheme: NHMRC Project Grants

Funding Amount: $1,106,169.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Invasive pneumococcal disease | Streptococcus pneumoniae | bacteraemia | in vivo expression | pathogenesis | pneumococcal infection | pneumococcus | pneumonia | sepsis | virulence gene