The regulation of pleiotropic responses by bidentate motifs embedded in the Fibroblast Growth Factor Receptors

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/626976

Funding Status
Closed

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Funded Activity Summary

Cells in our bodies are able to accomplish an impressive array of functions. Diffusible factors (called growth factors) are important in regulating diverse cellular functions. We have identified a new molecular switch inside cells that acts as a master controller of cellular functions. This molecular switch relays information to instruct specific cellular functions. We have shown that these molecular switches are short-circuited in breast cancer promoting cell growth and survival.

Funded Activity Details

Start Date: 01-01-2010

End Date: 01-01-2014

Funding Scheme: NHMRC Project Grants

Funding Amount: $489,336.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

angiogenesis | biochemistry | cancer | fibroblast growth factor receptors | fibroblast growth factors | intracellular signal transduction | neuronal cell death | organogenesis | protein phosphorylation | tissue regeneration

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